Robert J. Belland

CD66 receptor specificity exhibited by neisserial Opa variants is controlled by protein determinants in CD66 N-domains

Bos, Martine P., Kuroki, Motomu, Krop-Watorek, Anna, Hogan, Daniel, Belland, Robert J.

Neisseria gonorrhoeae strain MS11 is able to express 11 different opacity (Opa) proteins on its outer surface. A number of these Opa proteins have been shown to function as adhesins through binding...

Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes

Belland, Robert J., Scidmore, Marci A., Crane, Deborah D., Hogan, Daniel M., Whitmire, William, McClarty, Grant, ...

Chlamydia trachomatis is an obligate intracellular human bacterial pathogen that infects epithelial cells of the eye and genital tract. Infection can result in trachoma, the leading cause of...

Carcinoembryonic Antigen Family Receptor Recognition by Gonococcal Opa Proteins Requires Distinct Combinations of Hypervariable Opa Protein Domains

Bos, Martine P., Kao, David, Hogan, Daniel M., Grant, Christopher C. R., Belland, Robert J.

Neisserial Opa proteins function as a family of adhesins that bind heparan sulfate proteoglycan (HSPG) or carcinoembryonic antigen family (CEACAM) receptors on human host cells. In order to define...

Isolation of Chlamydia pneumoniae Clonal Variants by a Focus-Forming Assay

Gieffers, Jens, Belland, Robert J., Whitmire, William, Ouellette, Scot, Crane, Deborah, Maass, Matthias, ...

Chlamydia pneumoniae is an obligate intracellular prokaryotic human pathogen that causes community-acquired respiratory infection and has been associated with atherosclerosis and cardiovascular...

Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, ...

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase...

Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis

Belland, Robert J., Zhong, Guangming, Crane, Deborah D., Hogan, Daniel, Sturdevant, Daniel, Sharma, Jyotika, ...

Chlamydia trachomatis is one of the most common bacterial pathogens and is the etiological agent of debilitating sexually transmitted and ocular diseases in humans. The organism is an obligate...

Transcriptome analysis of chlamydial growth during IFN-γ-mediated persistence and reactivation

Belland, Robert J., Nelson, David E., Virok, Dezso, Crane, Deborah D., Hogan, Daniel, Sturdevant, Daniel, ...

Chlamydia trachomatis is an obligatory intracellular prokaryotic parasite that causes a spectrum of clinically important chronic inflammatory diseases of humans. Persistent infection may play a role...

Polymorphisms in the Chlamydia trachomatis Cytotoxin Locus Associated with Ocular and Genital Isolates

Carlson, John H., Hughes, Scott, Hogan, Daniel, Cieplak, Gordon, Sturdevant, Daniel E., McClarty, Grant, ...

Chlamydia trachomatis is a strict human pathogen producing infections that cause medically important chronic inflammatory diseases, such as blinding trachoma and tubal factor infertility. Isolates...

The Chlamydia pneumoniae Type III Secretion-Related lcrH Gene Clusters Are Developmentally Expressed Operons†

Ouellette, Scot P., AbdelRahman, Yasser M., Belland, Robert J., Byrne, Gerald I.

Two chlamydial homologues of the Yersinia lcrH chaperone for type III secretion system structural components are present within separate gene clusters. Quantitative transcriptional analyses...

CD66 receptor specificity exhibited by neisserial Opa variants is controlled by protein determinants in CD66 N-domains

Bos, Martine P., Kuroki, Motomu, Krop-Watorek, Anna, Hogan, Daniel, Belland, Robert J.

Neisseria gonorrhoeae strain MS11 is able to express 11 different opacity (Opa) proteins on its outer surface. A number of these Opa proteins have been shown to function as adhesins through binding...

Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes

Belland, Robert J., Scidmore, Marci A., Crane, Deborah D., Hogan, Daniel M., Whitmire, William, McClarty, Grant, ...

Chlamydia trachomatis is an obligate intracellular human bacterial pathogen that infects epithelial cells of the eye and genital tract. Infection can result in trachoma, the leading cause of...

Carcinoembryonic Antigen Family Receptor Recognition by Gonococcal Opa Proteins Requires Distinct Combinations of Hypervariable Opa Protein Domains

Bos, Martine P., Kao, David, Hogan, Daniel M., Grant, Christopher C. R., Belland, Robert J.

Neisserial Opa proteins function as a family of adhesins that bind heparan sulfate proteoglycan (HSPG) or carcinoembryonic antigen family (CEACAM) receptors on human host cells. In order to define...

Isolation of Chlamydia pneumoniae Clonal Variants by a Focus-Forming Assay

Gieffers, Jens, Belland, Robert J., Whitmire, William, Ouellette, Scot, Crane, Deborah, Maass, Matthias, ...

Chlamydia pneumoniae is an obligate intracellular prokaryotic human pathogen that causes community-acquired respiratory infection and has been associated with atherosclerosis and cardiovascular...

Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, ...

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase...

Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis

Belland, Robert J., Zhong, Guangming, Crane, Deborah D., Hogan, Daniel, Sturdevant, Daniel, Sharma, Jyotika, ...

Chlamydia trachomatis is one of the most common bacterial pathogens and is the etiological agent of debilitating sexually transmitted and ocular diseases in humans. The organism is an obligate...

Transcriptome analysis of chlamydial growth during IFN-γ-mediated persistence and reactivation

Belland, Robert J., Nelson, David E., Virok, Dezso, Crane, Deborah D., Hogan, Daniel, Sturdevant, Daniel, ...

Chlamydia trachomatis is an obligatory intracellular prokaryotic parasite that causes a spectrum of clinically important chronic inflammatory diseases of humans. Persistent infection may play a role...

Polymorphisms in the Chlamydia trachomatis Cytotoxin Locus Associated with Ocular and Genital Isolates

Carlson, John H., Hughes, Scott, Hogan, Daniel, Cieplak, Gordon, Sturdevant, Daniel E., McClarty, Grant, ...

Chlamydia trachomatis is a strict human pathogen producing infections that cause medically important chronic inflammatory diseases, such as blinding trachoma and tubal factor infertility. Isolates...

The Chlamydia pneumoniae Type III Secretion-Related lcrH Gene Clusters Are Developmentally Expressed Operons†

Ouellette, Scot P., AbdelRahman, Yasser M., Belland, Robert J., Byrne, Gerald I.

Two chlamydial homologues of the Yersinia lcrH chaperone for type III secretion system structural components are present within separate gene clusters. Quantitative transcriptional analyses...

Homologue Scanning Mutagenesis Reveals Cd66 Receptor Residues Required for Neisserial Opa Protein Binding

Bos, Martine P., Hogan, Daniel, Belland, Robert J.

The immunoglobulin-like family of CD66 antigens, present on human neutrophils and epithelial cells, are used as receptors for adhesins expressed by the pathogenic Neisseriae. N. gonorrhoeae strain...