Chemical Similarity and Threshold of Toxicological Concern (TTC) Approaches (2008)
Grace Patlewicz, Ana Gallegos Saliner, Manuela Pavan, Romualdo Benigni, Aynur Aptula, Arianna Bassan, ...
The mission of IHCP is to provide scientific support to the development and implementation of EU policies related to health and consumer protection. The IHCP carries out research to improve the...
Putting the Predictive Toxicology Challenge into perspective: reflections on the results (2003)
Benigni, Romualdo, Giuliani, Alessandro
Motivation: Chemical carcinogenicity is of primary interest, because it drives much of the current regulatory actions regarding new and existing chemicals, and its experimental determination involves...
Franke, Rainer, Gruska, Andreas, Giuliani, Alessandro, Benigni, Romualdo
The aromatic amines are widely used industrial chemicals and can be found in tobacco smoke as well as in products generated during cooking. In a previous study, we established quantitative...
Nonlinear methods in the analysis of protein sequences: a case study in rubredoxins (2000)
Ro Giuliani, Romualdo Benigni, Paolo Sirabella, Joseph P. Zbilut, Alfredo Colosimo
ABSTRACT Two computational methods widely used in time series analysis were applied to protein sequences, and their ability to derive structural information not directly accessible through classical...
Giuliani, Alessandro, Sirabella, Paolo, Benigni, Romualdo, Colosimo, Alfredo
Recurrence quantification analysis (RQA) was used to characterize the folding properties of 22 chimeric sequences derived from two parent proteins of similar length but different three-dimensional...
Relationships between in vitro mutagenicity assays (1992)
This paper analyzes the mutagenicity results reported by the US National Toxicology Program (NTP), relative to 41 chemicals assayed with four in vitro short-term tests [Salmonella typhimurium (STY),...
Estimate of the Genome Size by Renaturation Studies in Streptomyces
Benigni, Romualdo, Petrov, Peter Antonov, Carere, Angelo
The genome sizes of Streptomyces coelicolor and Streptomyces rimosus as calculated by deoxyribonucleic acid reassociation kinetics are approximately 10.5 × 106 nucleotide pairs.
Inequalities in health: the value of sex-related indicators.
My laboratory has previously shown that the sex differences in tumor incidence in Europe can be related to the female social condition and that the pattern of this relationship varies according to...
Estimate of the Genome Size by Renaturation Studies in Streptomyces
Benigni, Romualdo, Petrov, Peter Antonov, Carere, Angelo
The genome sizes of Streptomyces coelicolor and Streptomyces rimosus as calculated by deoxyribonucleic acid reassociation kinetics are approximately 10.5 × 106 nucleotide pairs.
Inequalities in health: the value of sex-related indicators.
My laboratory has previously shown that the sex differences in tumor incidence in Europe can be related to the female social condition and that the pattern of this relationship varies according to...