Mendes, Rodrigo E., Bell, Jan M., Turnidge, John D., Castanheira, Mariana, Jones, Ronald N.
Objectives The aim of this study was to evaluate the occurrence and dissemination of acquired carbapenem-hydrolysing class D β-lactamase (class D carbapenemase)- and metallo-β-lactamase...
Jones, Ronald N., Moet, Gary J., Sader, Helio S., Mendes, Rodrigo E., Castanheira, Mariana
Background TR-700, the active component of the oxazolidinone prodrug TR-701, has demonstrated potent activity against numerous Gram-positive species. In this study, single-step mutation frequencies,...
Sader, Helio S., Jones, Ronald N., Rossi, Kerri L., Rybak, Michael J.
Background The bactericidal activities of vancomycin and daptomycin were evaluated in a large collection of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia strains from nine major USA...
Mendes, Rodrigo E., Bell, Jan M., Turnidge, John Douglas, Castanheira, Mariana, Jones, Ronald N.
© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.
Mendes, Rodrigo E., Bell, Jan M., Turnidge, John Douglas, Castanheira, Mariana, Jones, Ronald N.
© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.
Fritsche, Thomas R., Rhomberg, Paul R., Sader, Helio S., Jones, Ronald N.
Objectives Omiganan pentahydrochloride is a cidal cationic peptide with a broad antimicrobial spectrum, including yeast, currently in development as a topical agent for the prevention of...
Chin, Judy N., Jones, Ronald N., Sader, Helio S., Savage, Paul B., Rybak, Michael J.
Objectives Previous data from our research had shown that the novel ceragenin, CSA-13, demonstrated concentration-dependent bactericidal activity against glycopeptide-resistant Staphylococcus aureus....
Toleman, Mark Alexander Howard, Bennett, Peter M., Bennett, David M. C., Jones, Ronald N., Walsh, Timothy Rutland
Trimethoprim/sulfamethoxazole (TMP/SMX) resistance remains a serious threat in the treatment of Stenotrophomonas maltophilia infections. We analyzed an international collection of 55 S. maltophilia...
Toleman, Mark Alexander Howard, Bennett, Peter M., Bennett, David M. C., Jones, Ronald N., Walsh, Timothy Rutland
Trimethoprim/sulfamethoxazole (TMP/SMX) resistance remains a serious threat in the treatment of Stenotrophomonas maltophilia infections. We analyzed an international collection of 55 S. maltophilia...
Bell, Jan M., Chitsaz, Mohsen, Turnidge, John Douglas, Barton, Mary D., Walters, Luke J., Jones, Ronald N.
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Biedenbach, Douglas J., Bell, Jan M., Sader, H S., Fritsche, Thomas R., Jones, Ronald N., Turnidge, John Douglas
Copyright © 2007 Elsevier B.V. and the International Society of Chemotherapy All rights reserved.
Experiences in deploying an MDS4 Grid Information System on the Australian National Grid (2007)
Galang, Gerson Casimiro, Coddington, Paul David, Fraser, Ryan, Jones, Ronald N., Sharpe, Andrew
http://www.apac.edu.au/apac07/
Bell, Jan M., Chitsaz, Mohsen, Turnidge, John Douglas, Barton, Mary D., Walters, Luke J., Jones, Ronald N.
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Biedenbach, Douglas J., Bell, Jan M., Sader, H S., Fritsche, Thomas R., Jones, Ronald N., Turnidge, John Douglas
Copyright © 2007 Elsevier B.V. and the International Society of Chemotherapy All rights reserved.
Experiences in deploying an MDS4 Grid Information System on the Australian National Grid (2007)
Galang, Gerson Casimiro, Coddington, Paul David, Fraser, Ryan, Jones, Ronald N., Sharpe, Andrew
http://www.apac.edu.au/apac07/
Soraya S Andrade, Helio S Sader, Ronald N Jones, Andrea S Pereira, Antônio CC Pignatari, Ana C Gales
Emerging resistance phenotypes and antimicrobial resistance rates among pathogens recovered from community-acquired urinary tract infections (CA-UTI) is an increasing problem in specific regions,...
Andrade,Soraya S, Sader,Helio S, Jones,Ronald N, Pereira,Andrea S, Pignatari,Antônio CC, Gales,Ana C
Emerging resistance phenotypes and antimicrobial resistance rates among pathogens recovered from community-acquired urinary tract infections (CA-UTI) is an increasing problem in specific regions,...
Watters, Amy A., Jones, Ronald N., Leeds, Jennifer A., Denys, Gerald, Sader, Helio S., Fritsche, Thomas R.
Objectives: To evaluate the spectrum of activity and potency of LBM415, the first of the peptide deformylase inhibitor (PDFI) class to be developed for treatment of community-acquired respiratory...
Comment on: Linezolid resistance in coagulase-negative staphylococci2 (2006)
Jones, Ronald N., Ross, James E., Fritsche, Thomas R., Sader, Helio S.
Watters, Amy A., Jones, Ronald N., Leeds, Jennifer A., Denys, Gerald, Sader, Helio S., Fritsche, Thomas R.
Objectives: To evaluate the spectrum of activity and potency of LBM415, the first of the peptide deformylase inhibitor (PDFI) class to be developed for treatment of community-acquired respiratory...
Comment on: Linezolid resistance in coagulase-negative staphylococci (2006)
Jones, Ronald N., Ross, James E., Fritsche, Thomas R., Sader, Helio S.
Jones, Ronald N., Ross, James E., Fritsche, Thomas R., Sader, Helio S.
Objectives: To investigate the activity of linezolid (an oxazolidinone), a potent choice for community- and hospital-acquired infections, via a worldwide surveillance network called the Zyvox®...
Ana C Gales, Ronald N Jones, Soraya S Andrade, Helio S Sader
The antimicrobial susceptibility of 176 unusual non-fermentative gram-negative bacilli (NF-GNB) collected from Latin America region through the SENTRY Program between 1997 and 2002 was evaluated by...
Gales,Ana C, Jones,Ronald N, Andrade,Soraya S, Sader,Helio S
The antimicrobial susceptibility of 176 unusual non-fermentative gram-negative bacilli (NF-GNB) collected from Latin America region through the SENTRY Program between 1997 and 2002 was evaluated by...
Gales,Ana C., Jones,Ronald N., Andrade,Soraya S., Pereira,Andrea S., Sader,Hélio S.
The in vitro activity of tigecycline (former GAR-936), a new semisynthetic tetracycline, was evaluated in comparison with tetracycline and other antimicrobial agents. MATERIAL AND METHODS: A total of...
Bell, Jan M., Turnidge, John Douglas, Inoue, Matsuhisa, Kohno, Shigeru, Hirakata, Yoichi, Ono, Yasuo, ...
Copyright © The British Society for Antimicrobial Chemotherapy 2005; all rights reserved.
Bell, Jan M., Turnidge, John Douglas, Inoue, Matsuhisa, Kohno, Shigeru, Hirakata, Yoichi, Ono, Yasuo, ...
Copyright © The British Society for Antimicrobial Chemotherapy 2005; all rights reserved.
Streit, Jennifer M., Steenbergen, Judith N., Thorne, Grace M., Alder, Jeffrey, Jones, Ronald N.
Objectives: To evaluate the activity of daptomycin tested against numerous species of viridans group streptococci and Streptococcus bovis, which are associated with wound infections, sepsis,...
Bell, Jan M., Turnidge, John D., Inoue, Matsuhisa, Kohno, Shigeru, Hirakata, Yoichi, Ono, Yasuo, ...
Streit, Jennifer M., Steenbergen, Judith N., Thorne, Grace M., Alder, Jeffrey, Jones, Ronald N.
Objectives: To evaluate the activity of daptomycin tested against numerous species of viridans group streptococci and Streptococcus bovis, which are associated with wound infections, sepsis,...
Jones, Ronald N., Fritsche, Thomas R., Ge, Yigong, Kaniga, Koné, Sader, Helio S.
Objectives: To evaluate bactericidal activity of PPI-0903M and in vitro testing parameters for this compound. Methods: A total of 110 strains were tested to determine MIC and MBC values of PPI-0903M....
Jones, Ronald N., Ross, James E., Fritsche, Thomas R., Sader, Helio S.
Objectives: To investigate the activity of linezolid (an oxazolidinone), a potent choice for community- and hospital-acquired infections, via a worldwide surveillance network called the Zyvox®...
Toleman, Mark A., Biedenbach, Doug, Bennett, David M. C., Jones, Ronald N., Walsh, Timothy R.
Objectives: As part of the SENTRY Antimicrobial Surveillance Programme, 383 non-replicative randomly collected Pseudomonas aeruginosa isolates were collected during 1999–2002. These strains...
Bell, Jan M., Turnidge, John D., Inoue, Matsuhisa, Kohno, Shigeru, Hirakata, Yoichi, Ono, Yasuo, ...
Jones, Ronald N., Fritsche, Thomas R., Ge, Yigong, Kaniga, Koné, Sader, Helio S.
Objectives: To evaluate bactericidal activity of PPI-0903M and in vitro testing parameters for this compound. Methods: A total of 110 strains were tested to determine MIC and MBC values of PPI-0903M....
Sader,Helio S., Jones,Ronald N., Gales,Ana C., Silva,Juliana B., Pignatari,Antonio C.
The alarming emergence and spread of antimicrobial resistance among common bacteria threatens the effectiveness of therapy for many infections. Surveillance of antimicrobial resistance is essential...
Jones, Ronald N., Huynh, Holly K., Biedenbach, Douglas J., Fritsche, Thomas R., Sader, Helio S.
Objectives: To investigate the potency of doripenem, a broad-spectrum carbapenem characterized by a wider spectrum of activity combining antimicrobial and bactericidal features of imipenem and...
Jones, Ronald N., Moet, Gary J., Sader, Helio S., Fritsche, Thomas R.
Objectives: To evaluate the potency of a novel peptide deformylase inhibitor, NVP PDF-713, against Gram-positive organisms having resistances to linezolid or quinupristin/dalfopristin. Materials and...
Messer, Shawn A., Kirby, Jeffrey T., Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
Objectives: This longitudinal study evaluated the in vitro activity of anidulafungin against 880 clinical yeast isolates and 68 mould isolates from 64 medical centres in North America, Latin America...
Mutnick, Alan H., Rhomberg, Paul R., Sader, Helio S., Jones, Ronald N.
Background: The MYSTIC Programme is a global, longitudinal antimicrobial surveillance network of hospitals that frequently utilize carbapenems. One aspect of the programme is the ability to capture...
Patzer, Jan, Toleman, Mark A., Deshpande, Lalitagauri M., Kamiska, Wanda, Dzieranowska, Danuta, Bennett, Peter M., ...
Objectives: During 1997-2001, 151 isolates of imipenem-resistant Pseudomonas aeruginosa were obtained from clinical specimens taken from children hospitalized in Warsaw, Poland. These strains were...
Daptomycin activity and spectrum: a worldwide sample of 6737 clinical Gram-positive organisms (2004)
Streit, Jennifer M., Jones, Ronald N., Sader, Helio S.
Background: Increasing antimicrobial resistance among bacterial pathogens has prompted attempts to develop new antimicrobial agents active against multidrug-resistant Gram-positive pathogens....
Jones, Ronald N., Moet, Gary J., Sader, Helio S., Fritsche, Thomas R.
Objectives: To evaluate the potency of a novel peptide deformylase inhibitor, NVP PDF-713, against Gram-positive organisms having resistances to linezolid or quinupristin/dalfopristin. Materials and...
Jones, Ronald N., Huynh, Holly K., Biedenbach, Douglas J., Fritsche, Thomas R., Sader, Helio S.
Objectives: To investigate the potency of doripenem, a broad-spectrum carbapenem characterized by a wider spectrum of activity combining antimicrobial and bactericidal features of imipenem and...
Messer, Shawn A., Kirby, Jeffrey T., Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
Objectives: This longitudinal study evaluated the in vitro activity of anidulafungin against 880 clinical yeast isolates and 68 mould isolates from 64 medical centres in North America, Latin America...
Toleman, Mark A., Biedenbach, Doug, Bennett, David M. C., Jones, Ronald N., Walsh, Timothy R.
Objectives: As part of the SENTRY Antimicrobial Surveillance Programme, 383 non-replicative randomly collected Pseudomonas aeruginosa isolates were collected during 1999-2002. These strains...
Mutnick, Alan H., Rhomberg, Paul R., Sader, Helio S., Jones, Ronald N.
Background: The MYSTIC Programme is a global, longitudinal antimicrobial surveillance network of hospitals that frequently utilize carbapenems. One aspect of the programme is the ability to capture...
Patzer, Jan, Toleman, Mark A., Deshpande, Lalitagauri M., Kaminska, Wanda, Dzierzanowska, Danuta, Bennett, Peter M., ...
Objectives: During 1997–2001, 151 isolates of imipenem-resistant Pseudomonas aeruginosa were obtained from clinical specimens taken from children hospitalized in Warsaw, Poland. These strains were...
Daptomycin activity and spectrum: a worldwide sample of 6737 clinical Gram-positive organisms (2004)
Streit, Jennifer M., Jones, Ronald N., Sader, Helio S.
Background: Increasing antimicrobial resistance among bacterial pathogens has prompted attempts to develop new antimicrobial agents active against multidrug-resistant Gram-positive pathogens....
Mendes,Rodrigo E., Reis,Adriana O., Gales,Ana C., Jones,Ronald N., Sader,Hélio S.
The accuracy of antimicrobial susceptibility tests is a crucial step for the clinical management of patients with serious infections. They must be reliable and precise because they will guide...
Walsh, Timothy R., Toleman, Mark A., Hryniewicz, Waleria, Bennett, Peter M., Jones, Ronald N.
As part of the SENTRY Antimicrobial Surveillance Program, an imipenem-resistant Pseudomonas aeruginosa strain (81-11963A) was isolated from the blood culture of a female neonate institutionalized at...
Multicentre evaluation of the in vitro activity of linezolid in the Western Pacific (2003)
Bell, Jan M., Turnidge, John D., Ballow, Charles H., Jones, Ronald N.
Multiresistance to antimicrobial agents is common in staphylococci and pneumococci isolates in the Western Pacific region. The activity of linezolid, a new oxazolidinone, was evaluated against a...
Multicentre evaluation of the in vitro activity of linezolid in the Western Pacific (2003)
Bell, Jan M., Turnidge, John D., Ballow, Charles H., Jones, Ronald N.
Multiresistance to antimicrobial agents is common in staphylococci and pneumococci isolates in the Western Pacific region. The activity of linezolid, a new oxazolidinone, was evaluated against a...
Walsh, Timothy R., Toleman, Mark A., Hryniewicz, Waleria, Bennett, Peter M., Jones, Ronald N.
As part of the SENTRY Antimicrobial Surveillance Program, an imipenem-resistant Pseudomonas aeruginosa strain (81-11963A) was isolated from the blood culture of a female neonate institutionalized at...
Toleman, Mark A., Biedenbach, Doug, Bennett, David, Jones, Ronald N., Walsh, Timothy R.
Objective: In 2001, as part of the SENTRY worldwide antimicrobial surveillance programme, Pseudomonas aeruginosa 86-14571A was isolated at a hospital in Rome from a cancer patient with a bloodstream...
Jones, Ronald N., Rhomberg, Paul R.
The antibacterial activity of NVP-PDF386 (VRC4887), a novel peptide deformylase (PDF) inhibitor, was tested against over 1000 recent clinical isolates collected during 2001 and 2002. The MIC50/90...
Toleman, Mark A., Biedenbach, Doug, Bennett, David, Jones, Ronald N., Walsh, Timothy R.
Objective: In 2001, as part of the SENTRY worldwide antimicrobial surveillance programme, Pseudomonas aeruginosa 86–14571A was isolated at a hospital in Rome from a cancer patient with a...
Multicentre evaluation of the in vitro activity of linezolid in the Western Pacific (2003)
Bell, Jan M., Turnidge, John D., Ballow, Charles H., Jones, Ronald N.
Multiresistance to antimicrobial agents is common in staphylococci and pneumococci isolates in the Western Pacific region. The activity of linezolid, a new oxazolidinone, was evaluated against a...
Walsh, Timothy R., Toleman, Mark A., Hryniewicz, Waleria, Bennett, Peter M., Jones, Ronald N.
As part of the SENTRY Antimicrobial Surveillance Program, an imipenem-resistant Pseudomonas aeruginosa strain (81-11963A) was isolated from the blood culture of a female neonate institutionalized at...
Toleman, Mark A., Biedenbach, Doug, Bennett, David, Jones, Ronald N., Walsh, Timothy R.
Objective: In 2001, as part of the SENTRY worldwide antimicrobial surveillance programme, Pseudomonas aeruginosa 86-14571A was isolated at a hospital in Rome from a cancer patient with a bloodstream...
Ballow,Charles H., Biedenbach,Douglas J., Rossi,Flavia, Jones,Ronald N.
Linezolid was the first clinically applied member of the new antimicrobial class called the "oxazolidinones". These agents have a powerful spectrum of activity focussed against Gram-positive...
Ronald N. Jones, Christopher M. Rubino, Sujata M. Bhavnani, Paul G. Ambrose
The use of fluoroquinolones for the treatment of community-acquired respiratory tract infection is increasing. Since for Streptococcus pneumoniae a ratio of the 24-h area under the concentration-time...
Gordon, Kelley A., Pfaller, Michael A., Jones, Ronald N.
BMS284756 is a novel des-F (6)-quinolone, which has a wide range of activity against many species of Gram-positive and -negative organisms. The potency of BMS284756 was compared with that of other...
Toleman, Mark A., Simm, Alan M., Murphy, Tanya A., Gales, Ana C., Biedenbach, Doug J., Jones, Ronald N., ...
The gene encoding the metallo-ß-lactamase SPM-1 was cloned from a genomic library of Pseudomonas aeruginosa strain 48-1997A. The insert carrying spm-1 possessed a GC content of 47%, indicating that...
Jones, Ronald N., Deshpande, Lalitagauri M., Mutnick, Alan H., Biedenbach, Douglas J.
Community-acquired and nosocomial infections caused by multidrug-resistant Gram-positive pathogens continue to increase in prevalence and have become a serious problem in many parts of the world....
Jones, Ronald N., Rhomberg, Paul R.
The antibacterial activity of NVP-PDF386 (VRC4887), a novel peptide deformylase (PDF) inhibitor, was tested against over 1000 recent clinical isolates collected during 2001 and 2002. The MIC50/90...
Jones, Ronald N., Deshpande, Lalitagauri M., Mutnick, Alan H., Biedenbach, Douglas J.
Community-acquired and nosocomial infections caused by multidrug-resistant Gram-positive pathogens continue to increase in prevalence and have become a serious problem in many parts of the world....
Toleman, Mark A., Simm, Alan M., Murphy, Tanya A., Gales, Ana C., Biedenbach, Doug J., Jones, Ronald N., ...
The gene encoding the metallo-&bgr;-lactamase SPM-1 was cloned from a genomic library of Pseudomonas aeruginosa strain 48-1997A. The insert carrying spm-1 possessed a GC content of 47%,...
Anderegg, Tamara R., Biedenbach, Douglas J., Jones, Ronald N.
Linezolid was the first clinically applied agent from the oxazolidinone class, and AZD2563, a new agent, is described here. Five hundred and twenty-five streptococcal isolates were tested, including...
Ambrose, Paul G., Owens, Robert C., Garvey, Michael J., Jones, Ronald N.
Pseudomonas aeruginosa is one of the more common and clinically difficult-to-treat causes of hospital-acquired infections. Cefepime is a broad-spectrum cephalosporin with potent in vitro activity...
Toleman, Mark A., Simm, Alan M., Murphy, Tanya A., Gales, Ana C., Biedenbach, Doug J., Jones, Ronald N., ...
The gene encoding the metallo-ß-lactamase SPM-1 was cloned from a genomic library of Pseudomonas aeruginosa strain 48-1997A. The insert carrying spm-1 possessed a GC content of 47%, indicating that...
Jones, Ronald N., Deshpande, Lalitagauri M., Mutnick, Alan H., Biedenbach, Douglas J.
Community-acquired and nosocomial infections caused by multidrug-resistant Gram-positive pathogens continue to increase in prevalence and have become a serious problem in many parts of the world....
Jones, Ronald N., Rhomberg, Paul R.
The antibacterial activity of NVP-PDF386 (VRC4887), a novel peptide deformylase (PDF) inhibitor, was tested against over 1000 recent clinical isolates collected during 2001 and 2002. The MIC50/90...
Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil (2001)
Sader,Helio S., Gales,Ana C., Jones,Ronald N.
The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from...
Sader,Helio S., Gales,Ana C., Pfaller,Michael A., Mendes,Rodrigo E., Zoccoli,Cássia, Barth,Afonso, ...
BACKGROUND: Pathogen frequency and resistance patterns may vary significantly from country to country and also in different hospitals within a country. Thus, regional surveillance programs are...
SADER,HÉLIO S., MENDES,RODRIGO E., GALES,ANA C., JONES,RONALD N., PFALLER,MICHAEL A., ZOCCOLI,CASSIA, ...
Introdução: Pneumonia hospitalar é a mais fatal das infecções hospitalares, com taxas de mortalidade de 30 a 60%. Estima-se que 15% de todas as mortes associadas à hospitalização estejam...
Sader,Helio S., Jones,Ronald N., Ballow,Charles H., Biedenbach,Douglas J., Cereda,Rosangela F.
Gram-positive cocci are important causes of both nosocomial and community-acquired infections, and antimicrobial resistance among these pathogens has become an important problem worldwide. Since...
Cereda,Rosangela F., Sader,Helio S., Jones,Ronald N., Sejas,Lilian, Machado,Antônia M., Zanatta,Yara P., ...
We report for the first time in Brazil, a patient from whom an Enterococcus faecalis VanA phenotype was isolated. Glycopeptide resistance is not commonly observed in Enterococcus faecalis, so this...
SADER,HÉLIO S., GALES,ANA C., REIS,ADRIANA O., ZOCCOLI,CASSIA, SAMPAIO,JORGE, JONES,RONALD N.
O tratamento da pneumonia adquirida na comunidade (PAC) é habitualmente empírico e o uso de antimicrobianos é baseado em estudos de vigilância. O programa SENTRY foi desenhado para monitorar a...
Gales, Ana C., Jones, Ronald N., Gordon, Kelley A., Sader, Hélio S., Wilke, Werner W., Beach, Mondell L., ...
The potency and spectrum of various antimicrobial agents tested against 434 bacterial isolates causing urinary tract infection (UTI) in hospitalized patients in Latin America were evaluated. The...
Jones, Ronald N., Deshpande, Lalitagauri M., Erwin, Meredith E., Barrett, Mary S., Beach, Mondell L.
Gemifloxacin is a novel quinolone with excellent activity against Gram-positive and some Gram-negative pathogens. Its activity was tested against 150 Neisseria gonorrhoeae strains, including 50...
Communicating information from antimicrobial resistance surveillance study data to microbiologists and physicians can be challenging. Large amounts of data, commonly reaching millions of MICs or zone...
Pfaller, Michael A., Jones, Ronald N.
The Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) programme aims to provide in vitro surveillance data for geographically diverse institutions where meropenem is available for...
Doern, Gary V., Brueggemann, Angela B., Perla, Rocco J., Daly, Jennifer S., Halkias, Demetrios, Jones, Ronald N., ...
A four-center study in which a total of 1,082 recent clinical isolates of members of the family Enterobacteriaceae and Pseudomonas aeruginosa were examined versus 11 antimicrobial agents with the...
Doern, Gary V., Jones, Ronald N., Gerlach, E. Hugh, Washington, John A., Biedenbach, Douglas J., Brueggemann, Angela B., ...
S1, a new chromogenic cephalosporin (International BioClinical, Inc., Portland, Oreg.), was used to detect beta-lactamase production among a variety of commonly encountered bacteria in a four-center...
Cormican, Martin G., Jones, Ronald N.
Clinafloxacin was significantly more active against fluoroquinolone-resistant organisms than ciprofloxacin, ofloxacin, sparfloxacin and fleroxacin. Clinafloxacin inhibited 65% of isolates at...
Cormican, Martin G., Jones, Ronald N.
Furopenem is a novel orally active penem. In this study, furopenem was highly active in vitro against Streptococcus pneumoniae (MIG90 0.03 mg/L), Haemophilus influenzae (MIC90, 2 mg/L), and...
Marshall, Steven A., Jones, Ronald N., Murray, Patrick R., Washington, John A., Allen, Stephen D., Gerlach, E. Hugh, ...
In-vitro studies of meropenem (1989)
Jones, Ronald N., Barry, Arthur L., Tbornsberry, Clyde
Meropenem, a new carbapenem, was compared with imipenem and seven other broad-spectrum antimicrobial agents against approximately 1000 clinical isolates. Meropenem was two- to four-fold more active...
Review of the in-vitro spectrum and characteristics of cefmetazole (CS-1170) (1989)
The in-vitro antimicrobial qualities of cefmetazole are summarized from a review of over 30 publications. Cefmetazole, a 7α-methoxy cephalosporin, is shown to have an antimicrobial spectrum closely...
Barry, Arthur L., Jones, Ronald N., Thornsberry, Clyde
The in-vitro activities of two penems (FCE 22101 and SCH 34343) were compared to those of a carbapenem (imipenem), a monobactam (aztreonam) and three cephalosporins (cefoperazone, ceftazidime, and...
Barry, Arthur L., Jones, Ronald N.
Tosufloxacin (A-61827) is the tosylate salt of A-60969 (T-3262). Temafloxacin (A-62254) is the hydrochloride salt of A-63004. Both compounds were tested against 945 aerobic bacterial isolates and...
Antimicrobial activity of LY163892, an orally administered 1-carbacephem (1988)
Jones, Ronald N., Barry, Arthur L.
LY163892 was found to be similar to cefaclor and slightly superior to cephalexin in antimicrobial activity and spectrum. Bacteria with MIC50 ≤8.0 mg/l included Escherichia coli, Kiebsiella...
Interpretative criteria for the agar diffusion susceptibility test with azithromycin (1988)
Barry, Arthur L., Jones, Ronald N.
Azithromycin (CP-62,993) is a macrolide with a tendency to concentrate in various body tissues. Difficulties that arise when establishing tentative minimum inhibitory concentration (MIC) breakpoints...
Jones, Ronald N., Barry, Arthur L., Fuchs, Peter C., Thornsberry, Clyde
Sch 34343 was compared with representative parenteral β-lactams including monobactams (aztreonam), I-oxa-β-lactams (latamoxef), carbapenems (imipenem) and cephalosporins (cefamandole, cefoperazone,...
The combination of cefotaxime and desacetylcefotaxime was tested against 83 Bacteroides strains (seven species) isolated from several hospitals. The combination greatly enhanced the anti-anaerobic...
Barry, Arthur L., Jones, Ronald N., Wilson, Harold W., Badal, Robert E., Thornsberry, Clyde
Microdilution susceptibility tests were performed with 527 clinical isolates collected from seven geographically separate institutions: 60% of the strains demonstrated some β-lactamase activity, as...
Barry, Arthur L., Jones, Ronald N.
Mezlocillin, carbenicillin, ticarcillin and piperacillin susceptibility data were reviewed and MIC breakpoints were proposed for classifying bacteria into three distinct categories of susceptibility:...
Public Health Consequences of Macrolide Use in Food Animals: A Deterministic Risk Assessment
Hurd, H. Scott, Doores, Stephanie, Hayes, Dermot J., Mathew, Alan, Maurer, John, Silley, Peter, ...
The potential impact on human health from antibiotic-resistant bacteria selected by use of antibiotics in food animals has resulted in many reports and recommended actions. The U.S. Food and Drug...
Seguin, Jennifer C., Walker, Robert D., Caron, John P., Kloos, Wesley E., George, Carol G., Hollis, Richard J., ...
During a 13-month period, 11 equine patients visiting a veterinary teaching hospital for various diagnostic and surgical procedures developed postprocedural infections from which methicillin...
Jones, Ronald N., Biedenbach, Douglas J., Erwin, Meredith E., Beach, Mondell L., Pfaller, Michael A.
In vitro antimicrobial activity and susceptibility testing interpretation criteria and quality control were studied for gatifloxacin, a new 8-methoxy fluoroquinolone, tested against Haemophilus...
Saiman, Lisa, Burns, Jane L., Whittier, Susan, Krzewinski, Jay, Marshall, Steve A., Jones, Ronald N.
The development of multidrug-resistant Pseudomonas aeruginosa in patients with cystic fibrosis (CF) is most likely a consequence of increasing life expectancy and more prolonged exposure to...
Tenover, Fred C., Jones, Ronald N., Swenson, Jana M., Zimmer, Barbara, McAllister, Sigrid, Jorgensen, James H.
A multilaboratory study was undertaken to determine the accuracy of the current National Committee for Clinical Laboratory Standards (NCCLS) oxacillin breakpoints for broth microdilution and disk...
Burns, Jane L., Saiman, Lisa, Whittier, Susan, Larone, Davise, Krzewinski, Jay, Liu, Zhenling, ...
Pseudomonas aeruginosa is the most common pathogen infecting the lungs of patients with cystic fibrosis (CF). Improved antimicrobial chemotherapy has significantly increased the life expectancy of...
Yamazumi, T., Marshall, S. A., Wilke, W. W., Diekema, D. J., Pfaller, M. A., Jones, Ronald N.
The Vitek automated susceptibility testing system with a modified Gram-Positive Susceptibility (GPS) 106 Card (bioMerieux Vitek, Inc., Hazelwood, Mo.) and a rapid slide latex agglutination test...
Gales, Ana C., Reis, Adriana O., Jones, Ronald N.
The emergence of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter spp. has necessitated the search for alternative parenteral agents such as the polymyxins. The...
Odland, Brant A., Erwin, Meredith E., Jones, Ronald N.
This multicenter study proposes antimicrobial susceptibility (MIC and disk diffusion methods) quality control (QC) parameters for seven compounds utilized in veterinary health. Alexomycin, apramycin,...
Doern, Gary V., Jones, Ronald N., Pfaller, Michael A., Kugler, Kari
Between February and June of 1997, a large number of community-acquired respiratory tract isolates of Haemophilus influenzae (n = 1,077) and Moraxella catarrhalis (n = 503) from 27 U.S. and 7...
Diekema, Daniel J., Coffman, Stacy L., Marshall, Steven A., Beach, Mondell L., Rolston, Kenneth V. I., Jones, Ronald N.
We report the in vitro activities of broad-spectrum β-lactam antimicrobials tested against 1,128 gram-positive pathogens recently isolated from cancer patients. Cefepime and imipenem were more...
Lewis, Russell E., Klepser, Michael E., Ernst, Erika J., Lund, Brian C., Biedenbach, Douglas J., Jones, Ronald N.
We have previously described the activity of low-dose clindamycin in extended-interval dosing regimens by determination of bactericidal titer in serum. In this study, we used a one-compartment in...
Gales, Ana, Sader, Helio, Jones, Ronald N.
The antimicrobial activity of BMS 284756, a novel des-F(6)-quinolone, was comparatively evaluated against 257 Streptococcus pneumoniae, 198 Haemophilus influenzae, and 88 Moraxella catarrhalis...
Gordon, Kelley A., Fusco, Judy, Biedenbach, Douglas J., Pfaller, Michael A., Jones, Ronald N.
Reports of an increased clinical incidence of pertussis and the development of resistance by Bordetella pertussis to erythromycin prompted the collection and testing of recent clinical isolates from...
Molecular Analysis of Tn1546 in Enterococcus faecium Isolated from Animals and Humans
Jensen, Lars Bogø, Ahrens, Peter, Dons, Lone, Jones, Ronald N., Hammerum, Anette M., Aarestrup, Frank Møller
The internal areas and the position of integration of the glycopeptide resistance element Tn1546 were characterized by using PCR fragment length polymorphism, sequencing, and DNA hybridization...
Pfaller, Michael A., Jones, Ronald N., Doern, Gary V., Kugler, Kari, Group, The Sentry Participants
The SENTRY Program was established in January 1997 to measure the predominant pathogens and antimicrobial resistance patterns of nosocomial and community-acquired infections over a broad network of...
Yu, Wen Liang, Winokur, Patricia L., Von Stein, Diana L., Pfaller, Michael A., Wang, Jen Hsien, Jones, Ronald N.
Klebsiella pneumoniae isolates from Taiwan medical centers (50 strains; 1998 to 2000) with a CTX-M resistance phenotype (ceftazidime susceptible and ceftriaxone or cefotaxime nonsusceptible) were...
In Vitro Evaluation of AZD2563, a Novel Oxazolidinone, against 603 Recent Staphylococcal Isolates
Anderegg, Tamara R., Biedenbach, Douglas J., Jones, Ronald N.
AZD2563, a novel oxazolidinone, and a selection of comparator drugs that included linezolid, erythromycin, clindamycin, quinolones, and gentamicin were tested against 384 Staphylococcus aureus (176...
Jones, Ronald N., Mutnick, Alan H., Varnam, David J.
The revised interpretive criteria for Streptococcus pneumoniae recently published in the NCCLS M100-S12 informational supplement provide two sets of breakpoints for some cephalosporins: one set for...
Jones, Ronald N., Rubino, Christopher M., Bhavnani, Sujata M., Ambrose, Paul G.
The use of fluoroquinolones for the treatment of community-acquired respiratory tract infection is increasing. Since for Streptococcus pneumoniae a ratio of the 24-h area under the concentration-time...
Biochemical Characterization of the Acquired Metallo-β-Lactamase SPM-1 from Pseudomonas aeruginosa
Murphy, Tanya A., Simm, Alan M., Toleman, Mark A., Jones, Ronald N., Walsh, Timothy R.
SPM-1 is a new metallo-β-lactamase recently identified in Pseudomonas aeruginosa strain 48-1997A, isolated in Sao Paulo, Brazil. Kinetic analysis demonstrated that SPM-1 has a broad hydrolytic...
Jones, Ronald N., Pfaller, Michael A., Rhomberg, Paul R., Walter, Donald H.
Tiamulin is a pleuromutilin derivative used in veterinary practice for the control and specific therapy of infections in swine. This report summarizes studies to establish standardized susceptibility...
Diekema, Daniel J., Andrews, Janet I., Huynh, Holly, Rhomberg, Paul R., Doktor, Stella R., Beyer, Jill, ...
Pulsed-field gel electrophoresis (PFGE) was performed on 122 neonatal bloodstream isolates of group B streptococci (GBS) to further examine the relationship between macrolide resistance and serotype...
Jones, Ronald N., Farrell, David J., Morrissey, Ian
Resistance to quinupristin-dalfopristin (Q/D) among gram-positive cocci has been very uncommon. Two clinical isolates among 8,837 (0.02%) Streptococcus pneumoniae isolates were discovered in 2001 to...
Gordon, Kelley A., Rhomberg, Paul R., Jones, Ronald N.
Results from garenoxacin dry-form broth microdilution MIC panels prepared commercially (Sensititre, TREK Diagnostics) were compared to reference frozen-form MICs to ensure the validity of the...
Fuchs, Peter C., Jones, Ronald N., Thornsberry, Clyde, Barry, Arthur L., Gerlach, E. Hugh, Sommers, Herbert M.
The in vitro activity of cefmenoxime (SCE-1365) was evaluated in a multiphased collaborative investigation. Over 7,500 consecutive clinical isolates were tested in five laboratories, and greater than...
Toleman, Mark A., Rolston, Kenneth, Jones, Ronald N., Walsh, Timothy R.
As part of the CANCER Antimicrobial Surveillance Program in North America, a clinical strain of Pseudomonas aeruginosa, strain 07-406, isolated in Texas was found to be resistant to all...
Jones, Ronald N., Fuchs, Peter C., Sniderman, Steve
A slightly modified Moeller medium for amino acid decarboxylase and dihydrolase testing by the replicator method correlated 96 to 99% with the reference Moeller broth method. False positive results...
Multiple-Inocula (Replicator) CAMP Test for Presumptive Identification of Group B Streptococci
Fuchs, Peter C., Christy, Carol, Jones, Ronald N.
A replicator method for performing the CAMP test is described. Of 304 group B streptococci tested, 303 (99.7%) were CAMP positive. None of 1,093 non-group B streptococci was CAMP positive.
Toleman, Mark A., Rolston, Kenneth, Jones, Ronald N., Walsh, Timothy R.
As part of the CANCER Antimicrobial Surveillance Program in North America, a Pseudomonas aeruginosa isolate, strain 07-406, was shown to possess a metallo-β-lactamase, designated VIM-7. blaVIM-7 is...
Sader, Helio S., Johnson, David M., Jones, Ronald N.
LB 11058 is a novel parenteral cephalosporin with a C-3 pyrimidinyl-substituted vinyl sulfide group and a C-7 2-amino-5-chloro-1,3-thiazole group. This study evaluated the in vitro activity and...
Yu, Wen-Liang, Cheng, Kuo-Chen, Wu, Lii-Tzu, Pfaller, Michael A., Winokur, Patricia L., Jones, Ronald N.
Kirby, Jeffrey T., Sader, Helio S., Walsh, Timothy R., Jones, Ronald N.
Limited data are available on Chryseobacterium spp. leading to an evaluation of the patient demographics and susceptibility patterns for Chryseobacterium spp. collected in the first 5 years of the...
Jones, Ronald N., Fuchs, Peter C., Gavan, Thomas L., Gerlach, E. Hugh, Barry, A. L., Thornsberry, Clyde
Cefuroxime, a new parenteral cephalosporin was compared with cephalothin by broth microdilution susceptibility testing against 5,887 routine clinical bacterial isolates in four large clinical...
Mendes, Rodrigo E., Castanheira, Mariana, Garcia, Patricia, Guzman, Manuel, Toleman, Mark A., Walsh, Timothy R., ...
Jones, Ronald N., Fuchs, Peter C.
Broth dilution antimicrobial susceptibility tests and biochemical identification of Bacteroides fragilis subspecies were performed by micromethods, yielding results within 48 to 72 h of isolation....
Jones, Ronald N., Fuchs, Peter C.
Antimicrobial susceptibility to cefamandole versus cephalothin and cefazolin versus cephalothin was compared by the broth microdilution method against 3,000 and 5,895 clinical bacterial isolates,...
Sader, Helio S., Fedler, Kelley A., Rennie, Robert P., Stevens, Shelley, Jones, Ronald N.
The activity of omiganan pentahydrochloride (formerly MBI 226; a synthetic cationic peptide) was assessed against 1,437 recent clinical bacterial isolates and 214 recent clinical yeast isolates. The...
Activities of Doripenem (S-4661) against Drug-Resistant Clinical Pathogens
Jones, Ronald N., Huynh, Holly K., Biedenbach, Douglas J.
Doripenem (formerly S-4661), a new 1-β-methyl carbapenem, was challenged with a worldwide collection of 394 drug-refractory isolates. For endemic extended-spectrum β-lactamase- and stably...
Castanheira, Mariana, Toleman, Mark A., Jones, Ronald N., Schmidt, Franz J., Walsh, Timothy R.
As part of the SENTRY Antimicrobial Surveillance Program in 2002, five multidrug-resistant Pseudomonas aeruginosa clinical isolates were detected with metallo-β-lactamase (MβL) activity. The...
Mendes, Rodrigo E., Toleman, Mark A., Ribeiro, Julival, Sader, Helio S., Jones, Ronald N., Walsh, Timothy R.
Since January 2002 Pseudomonas sp. strains resistant to carbapenems and ceftazidime have been routinely screened as part of the SENTRY Antimicrobial Surveillance Program for metallo-β-lactamase...
Jones, Ronald N., Anderegg, Tamara R., Swenson, Jana M.
An eight-laboratory study addressed the urgent need for quality control (QC) ranges for susceptibility determination when testing colistin (polymyxin E) and polymyxin B, two polycationic peptide...
Fritsche, Thomas R., Sader, Helio S., Cleeland, Roy, Jones, Ronald N.
LBM415 (NVP PDF-713) is the first member of the peptide deformylase (PDF) inhibitor class being developed for clinical trials as a parenteral and oral agent for treatment of community-acquired...
Booker, Brent M., Smith, Patrick F., Forrest, Alan, Bullock, Julie, Kelchlin, Pamela, Bhavnani, Sujata M., ...
Salmonella enterica serotype Typhi and nontyphoidal Salmonella remain major causes of morbidity and mortality worldwide. Ampicillin, trimethoprim-sulfamethoxazole, and chloramphenicol no longer...
Sader, Helio S., Fritsche, Thomas R., Kaniga, Koné, Ge, Yigong, Jones, Ronald N.
PPI-0903M is a novel N-phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of...
McDermott, Patrick F., Bodeis-Jones, Sonya M., Fritsche, Thomas R., Jones, Ronald N., Walker, Robert D.
Quality control ranges were developed for broth microdilution testing of Campylobacter jejuni ATCC 33560 against 14 antimicrobials. Cation-adjusted Mueller-Hinton broth containing 2.5% laked horse...
Hammel, Jeffrey P., Bhavnani, Sujata M., Jones, Ronald N., Forrest, Alan, Ambrose, Paul G.
In order to identify patients likely to be infected with resistant bacterial pathogens, analytic methods such as standard regression (SR) may be applied to surveillance data to determine patient- and...
McDermott, Patrick F., Bodeis-Jones, Sonya M., Fritsche, Thomas R., Jones, Ronald N., Walker, Robert D.
Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
One hundred recent clinical Pseudomonas aeruginosa isolates were used to assess the quantitative (MIC) and qualitative (susceptibility category) accuracies of the MicroScan WalkAway, VITEK, and VITEK...
Messer, Shawn A., Jones, Ronald N., Fritsche, Thomas R.
During 2003, a total of 1,397 Candida isolates, 73 Aspergillus isolates, 53 Cryptococcus neoformans isolates, and 25 other fungal isolates from infected, normally sterile, body sites in patients...
Jones, Ronald N., Sader, Helio S., Fritsche, Thomas R., Hogan, Patricia A., Sheehan, Daniel J.
The immediate lack of market-dominating commercial products (Vitek or MicroScan) for susceptibility testing of the new glycolipopeptide, dalbavancin, requires a surrogate marker agent to assist...
Jones, Ronald N., Fritsche, Thomas R., Sader, Helio S., Ross, James E.
Retapamulin (SB-275833), the first pleuromutilin to be developed for human topical use, was tested against a selected population of staphylococci and β-hemolytic streptococci. The MIC90 results for...
Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
A total of 207 Staphylococcus aureus strains, including 105 well-characterized strains with decreased susceptibility to vancomycin (17 vancomycin-intermediate S. aureus [VISA] and 88 heteroresistant...
Fritsche, Thomas R., Rennie, Robert P., Goldstein, Beth P., Jones, Ronald N.
While standardized microdilution testing methodologies and quality control ranges exist for the novel glycolipopeptide dalbavancin, no testing methods have been described that are immediately...
Jevitt, Laura A., Thorne, Grace M., Traczewski, Maria M., Jones, Ronald N., McGowan, John E., Tenover, Fred C., ...
Daptomycin is a novel cyclic lipopeptide that is approved by the U.S. Food and Drug Administration for the treatment of complicated skin and skin structure infections associated with Staphylococcus...
Deshpande, Lalitagauri M., Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
A total of 7,860 community-acquired Moraxella catarrhalis isolates (SENTRY Antimicrobial Surveillance Program, 1997 to 2004) were tested by broth microdilution methods, and 399 randomly selected...
Kosowska-Shick, Klaudia, Smith, Kathy, Bogdanovich, Tatiana, Ednie, Lois M., Jones, Ronald N., Appelbaum, Peter C.
Against 198 viridans group streptococci, 25 Streptococcus bovis strains, and 5 Cardiobacterium hominis strains, MICs of DX-619, a des-F(6)-quinolone, were between 0.004 and 0.25 μg/ml. These MICs...
Biedenbach, Douglas J., Ross, James E., Fritsche, Thomas R., Sader, Helio S., Jones, Ronald N.
Dalbavancin is a lipoglycopeptide antimicrobial agent with a potency significantly better than that of vancomycin when tested against staphylococci and streptococci. These two pathogens are common...
Jones, Ronald N., Stilwell, Matthew G., Hogan, Patricia A., Sheehan, Daniel J.
Linezolid was tested against 32 species of uncommonly isolated gram-positive organisms (3,251 strains) by reference MIC methods and found to be highly active (MIC50 range, 0.25 to 2 μg/ml; MIC90...
Bell, Jan M., Chitsaz, Mohsen, Turnidge, John D., Barton, Mary, Walters, Luke J., Jones, Ronald N.
A negative extended-spectrum β-lactamase (ESBL) confirmation test result obtained after a positive ESBL screening test result using Clinical and Laboratory Standards Institute methods has been a...
Sader, Helio S., Ferraro, Mary J., Reller, L. Barth, Schreckenberger, Paul C., Swenson, Jana M., Jones, Ronald N.
We reevaluated Enterobacteriaceae disk diffusion breakpoints for the tetracyclines published in the Clinical and Laboratory Standards Institute (CLSI) document M100-S16, which were...
Mendes, Rodrigo E., Castanheira, Mariana, Toleman, Mark A., Sader, Helio S., Jones, Ronald N., Walsh, Timothy R.
Seven blaIMP-1-harboring Acinetobacter sp. isolates and one Pseudomonas putida clinical isolate were recovered from hospitalized patients. All isolates possessed a class 1 integron, named In86,...
Jones, Ronald N., Nilius, Angela M., Akinlade, Bolanle K., Deshpande, Lalitagauri M., Notario, Gerard F.
A clinical trial of uncomplicated skin and skin structure infections (39 locations in 19 states) observed that community-associated or community-onset methicillin-resistant Staphylococcus aureus...
Rennie, Robert P., Koeth, Laura, Jones, Ronald N., Fritsche, Thomas R., Knapp, Cindy C., Killian, Scott B., ...
Performance of antimicrobial susceptibility tests with new agents requires careful consideration of the properties of the antimicrobial to ensure that the tests are standardized, reproducible, and...
Castanheira, Mariana, Sader, Hélio S., Deshpande, Lalitagauri M., Fritsche, Thomas R., Jones, Ronald N.
A total of 104 carbapenemase (serine- and metallo-β-lactamase [MβL])-producing strains of the Enterobacteriaceae family collected from 2000 to 2005 in medical centers distributed worldwide were...
Fritsche, Thomas R., Rhomberg, Paul R., Sader, Helio S., Jones, Ronald N.
Omiganan, a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections, inhibited commonly occurring fungal pathogens including...
Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
Two investigational anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) β-lactams, ceftaroline (a cephalosporin) and ME1036 (a carbapenem), were subjected to susceptibility testing by...
Fritsche, Thomas R., Castanheira, Mariana, Miller, George H., Jones, Ronald N., Armstrong, Eliana S.
The alteration of ribosomal targets by recently described 16S rRNA methyltransferases confers resistance to most aminoglycosides, including arbekacin. Enterobacteriaceae and nonfermentative bacilli...
Mendes, Rodrigo E., Deshpande, Lalitagauri M., Castanheira, Mariana, DiPersio, Joseph, Saubolle, Michael A., Jones, Ronald N.
Linezolid resistance has dominantly been mediated by mutations in 23S rRNA or ribosomal protein L4 genes. Recently, cfr has demonstrated the ability to produce a phenotype of resistance to not only...
Li, Hongyang, Toleman, Mark A., Bennett, Peter M., Jones, Ronald N., Walsh, Timothy R.
An outbreak involving a Pseudomonas aeruginosa strain that was resistant to all tested antimicrobials except polymyxin B occurred in a hospital in Houston, TX. Previous studies on this strain showed...
Rybak, Michael J., Leonard, Steve N., Rossi, Kerri L., Cheung, Chrissy M., Sadar, Helio S., Jones, Ronald N.
We screened for heteroresistant, vancomycin-intermediate Staphylococcus aureus (hVISA) among clinical isolates of methicillin-resistant S. aureus collected from three hospitals (two urban teaching...
Jones, Ronald N., Fritsche, Thomas R., Sader, Helio S.
The activity of DC-159a, a novel orally administered fluorinated quinolone, was evaluated by reference broth microdilution or agar dilution methods against 1,149 recently collected clinical isolates...
Rybak, Michael J., Leonard, Steve N., Rossi, Kerri L., Cheung, Chrissy M., Sader, Helio S., Jones, Ronald N.
Mendes, Rodrigo E., Bell, Jan M., Turnidge, John D., Castanheira, Mariana, Deshpande, Lalitagauri M., Jones, Ronald N.
Case Report of Aurantimonas altamirensis Bloodstream Infection▿
Mendes, Rodrigo E., Denys, Gerald A., Fritsche, Thomas R., Jones, Ronald N.
Castanheira, Mariana, Bell, Jan M., Turnidge, John D., Mathai, Dillip, Jones, Ronald N.
Among 57 metallo-β-lactamase (MβL)-producing Pseudomonas spp. detected in India during 2006, five blaVIM genes were found, including a newly characterized blaVIM gene. Pseudomonas aeruginosa...
Fritsche, Thomas R., Biedenbach, Douglas J., Jones, Ronald N.
Prulifloxacin, the prodrug of ulifloxacin (active component), is a newer fluoroquinolone with broad activity against enteric and nonenteric gram-negative bacilli. Ulifloxacin and other oral...
Activities of Dalbavancin against a Worldwide Collection of 81,673 Gram-Positive Bacterial Isolates▿
Biedenbach, Douglas J., Bell, Jan M., Sader, Helio S., Turnidge, John D., Jones, Ronald N.
Dalbavancin, a long-acting lipoglycopeptide, was evaluated against 81,673 isolates of staphylococci, enterococci, and streptococci collected from 33 countries during worldwide resistance surveillance...
Toleman, Mark A., Bennett, Peter M., Bennett, David M.C., Jones, Ronald N., Walsh, Timothy R.
The first sul2 genes have been found in S. maltophilia from several different countries.
Yu, Wen Leong, Pfaller, Michael A., Winokur, Patricia L., Jones, Ronald N.
To guide selection of carbapenems or fourth-generation cephalosporins as therapy, 110 Klebsiella pneumoniae isolates with extended-spectrum β-lactamases from Taiwan were characterized by phenotypic...
Potency and Bactericidal Activity of Iclaprim against Recent Clinical Gram-Positive Isolates▿
Sader, Helio S., Fritsche, Thomas R., Jones, Ronald N.
The in vitro activity of iclaprim, a novel diaminopyrimidine derivative, was evaluated against 5,937 recent gram-positive clinical isolates collected in the United States and Europe. Iclaprim...