Modeling the skin pattern of fishes (2009)
Barrio, R. A., Baker, Ruth E., Vaughan, JR., B., Tribuzy, K., De Carvalho, M. R., Bassanezi, R., ...
Complicated patterns showing various spatial scales have been obtained in the past by coupling Turing systems in such a way that the scales of the independent systems resonate. This produces...
Baker, Ruth E., Schnell, S., Maini, P. K.
In this article we will discuss the integration of developmental patterning mechanisms with waves of competency that control the ability of a homogeneous field of cells to react to pattern forming...
Reptile scale paradigm: Evo-Devo, pattern formation and regeneration (2009)
Chang, C., Wu, P., Baker, Ruth E., Maini, P. K., Alibardi, L., Chuong, C. M.
The purpose of this perspective is to highlight the merit of the reptile integument as an experimental model. Reptiles represent the first amniotes. From stem reptiles, extant reptiles, birds and...
From microscopic to macroscopic descriptions of cell migration on growing domains (2009)
Baker, Ruth E., Yates, C. A., Erban, R.
Cell migration and growth are essential components of the development of multicellular organisms. The role of various cues in directing cell migration is widespread, in particular, the role of...
DEVELOPMENTAL BIOLOGY The Turing Model Comes of Molecular Age (2008)
Philip K. Maini, Ruth E. Baker, Cheng-ming Chuong
nisms that give rise to complex patterns in biology? Despite recent advances in biotechnology and mathematical modeling, this still remains a largely open question. As reported on page xxx of this...
All B. Widelitz, Ruth E. Baker, Maksim Plikus, Chih-min Lin, Philip K. Maini, Ralf Paus, ...
Patterns form with the break of homogeneity and lead to the emergence of new structure or arrangement. There are different physiological and pathological mechanisms that lead to the formation of...
for a Stipendiary Lectureship in Applied Mathematics. (2008)
Ruth E. Baker, Professor Philip Maini, Dr. Santiago
Schnell for their unwavering support and guidance. To Philip for introducing me to the world of mathematical biology as an undergraduate, for suggestions with the mathematics, and for support in...
DEVELOPMENTAL BIOLOGY The Turing Model Comes of Molecular Age (2008)
Philip K. Maini, Ruth E. Baker, Cheng-ming Chuong
nisms that give rise to complex patterns in biology? Despite recent advances in biotechnology and mathematical modeling, this still remains a largely open question. As reported on page 1447 of this...
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration (2008)
Maksim V. Plikus, Julie Ann Mayer, Damon De La Cruz, Ruth E. Baker, Philip K. Maini, Robert Maxson, ...
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration (2008)
Plikus, M. V., Mayer, J. A., De La Cruz, D., Baker, Ruth E., Maini, P. K., Maxson, R., ...
In the age of stem cell engineering it is critical to understand how stem cell activity is regulated during regeneration. Hairs are mini-organs that undergo cyclic regeneration throughout adult...
Lin, C., Jiang, T., Baker, Ruth E., Maini, P., Hughes, M., Widelitz, R., ...
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Partial differential equations for self-organization in cellular and developmental biology (2008)
Baker, Ruth E., Gaffney, E. A., Maini, P. K.
Understanding the mechanisms governing and regulating the emergence of structure and heterogeneity within cellular systems, such as the developing embryo, represents a multiscale challenge typifying...
A mechanism for morphogen-controlled domain growth (2007)
Many developmental systems are organised via the action of graded distributions of morphogens. In the Drosophila wing disc, for example, recent experimental evidence has shown that graded expression...
A study of the temperature dependence of bienzyme systems and enzymatic chains (2007)
Kotov, N. V., Baker, Ruth E., Platov, K. V., Valeyev, N. V., Skorinkin, A. I., Maini, P. K.
It is known that most enzyme-facilitated reactions are highly temperature dependent processes. In general, the temperature coefficient, Q10, of a simple reaction reaches 2.0-3.0. Nevertheless, some...
Yamada, H., Nakagaki, T., Baker, Ruth E., Maini, P. K.
In the large amoeboid organism Physarum, biochemical oscillators are spatially distributed throughout the organism and their collective motion exhibits phase waves, which carry physiological signals....
Travelling gradients in interacting morphogen systems (2007)
Morphogen gradients are well known to play several important roles in development; however the mechanisms underlying the formation and maintenance of these gradients are often not well understood. In...
Kulesa, P. M., Schnell, S., Rudloff, S., Baker, Ruth E., Maini, P. K.
One of the most visually striking patterns in the early developing embryo is somite segmentation. Somites form as repeated, periodic structures in pairs along nearly the entire caudal vertebrate...
Modelling spatio-temporal starch degradation patterns in apples during fruit growth (2007)
Scheerlinck, N., Escudero, C., Baker, Ruth E., Maini, P. K.
This group, which is concerned with the applications of mathematics to agricultural science, was formed in 1970 and has since met at approximately yearly intervals in London for one-day meetings. The...
Mathematical models for somite formation (2007)
Baker, Ruth E., Schnell, S., Maini, P. K.
Somitogenesis is the process of division of the anterior–posterior vertebrate embryonic axis into similar morphological units known as somites. These segments generate the prepattern which guides...
A mathematical basis for the clock and wavefront model for somitogenesis (2007)
Baker, Ruth E., Schnell, S., Maini, P. K.
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Distinct mechanisms underlie pattern formation in the skin and skin appendages (2006)
Widelitz, R. B., Baker, Ruth E., Plikus, M., Lin, C., Maini, P. K., Paus, R., ...
Patterns form with the break of homogeneity and lead to the emergence of new structure or arrangement. There are different physiological and pathological mechanisms that lead to the formation of...
A clock and wavefront mechanism for somite formation (2006)
Baker, Ruth E., Schnell, S., Maini, P. K.
Somitogenesis, the sequential formation of a periodic pattern along the antero-posterior axis of vertebrate embryos, is one of the most obvious examples of the segmental patterning processes that...
A mathematical investigation of a clock and wavefront model for somitogenesis (2006)
Baker, Ruth E., Schnell, S., Maini, P. K.
Abstract Somites are transient blocks of cells that form sequentially along the antero-posterior axis of vertebrate embryos. They give rise to the vertebrae, ribs and other associated features of the...
The turing model comes of molecular age (2006)
Maini, P. K., Baker, Ruth E., Chuong, C. M.
Molecular analysis of hair follicle formation provide evidence to support the most well-known mathematical model for biological pattern formation.
Somitogenesis, the sequential formation of a periodic pattern along the antero-posterior axis of vertebrate embryos, is one of the most obvious examples of the segmental patterning processes that...
Somitogenesis, the sequential formation of a periodic pattern along the antero-posterior axis of vertebrate embryos, is one of the most obvious examples of the segmental patterning processes that...
Baker, Ruth E., Maini, Philip K., Thesis Advisor., Schnell, Santiago, Thesis Advisor., University Of Oxford. Mathematical And Physical Sciences Division. Thesis.
BLDSC reference no.: D233836.
McInerney, D., Schnell, S., Baker, Ruth E., Maini, P. K.
In this work we present an analysis, supported by numerical simulations, of the formulation of the cell-cycle model for somitogenesis proposed in Collier et al.(J. Theor. Biol. 207 (2000),...
Formation of vertebral precursors: Past models and future predictions (2003)
Baker, Ruth E., Schnell, S., Maini, P. K.
Disruption of normal vertebral development results from abnormal formation and segmentation of the vertebral precursors, called somites. Somitogenesis, the sequential formation of a periodic pattern...
Baker, Ruth E., University Of Michigan. School Of Public Health.
Thesis (M.S.P.H.)--University of Michigan, 1937.
How can mathematics help us explore vertebrate segmentation?
Baker, Ruth E., Schnell, Santiago
Since the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation...