Release of 5-aminosalicylic acid from Pentasa during normal and accelerated intestinal transit time.
Christensen, L A, Slot, O, Sanchez, G, Boserup, J, Rasmussen, S N, Bondesen, S, ...
The influence of intestinal transit time on the release of 5-aminosalicylic acid (5-ASA) from a peroral, slow-release preparation (Pentasa) was studied at steady state in seven healthy volunteers....
Absorption of 5-aminosalicylic acid from colon and rectum.
Bondesen, S, Schou, J B, Pedersen, V, Rafiolsadat, Z, Hansen, S H, Hvidberg, E F
In order to clarify the characteristics of absorption of 5-aminosalicylic acid (5-ASA) from the colon, a neutral solution was instilled into the right part of the colon and the rectum, respectively,...
Kinetics of 5-aminosalicylic acid after jejunal instillation in man.
Haagen Nielsen, O, Bondesen, S
The human pharmacokinetics of 5-aminosalicylic acid (5-ASA), the active moiety of salazosulphapyridine (SASP), is only known from studies in which rapid absorption has been deliberately avoided. The...