S. Magez

Details der Publikationsliste

Zeitraum

2002 - 2008

Anzahl

21

Co-Autoren

The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice (2008)

Magez, S., Schwegmann, A., Atkinson, R., Claes, F., Drennan, M., De Baetselier, P., ...

African trypanosomes are extracellular parasitic protozoa, predominantly transmitted by the bite of the haematophagic tsetse fly. The main mechanism considered to mediate parasitemia control in a...

Deletion of IL-4Rά on CD4 T Cells Renders BALB/c Mice Resistant to Leishmania major Infection (2007)

Radwanska, M., Cutler, A.J., Hoving, J.C., Magez, S., Holscher, C., Bohms, A., ...

Effector responses induced by polarized CD4þ T helper 2 (Th2) cells drive nonhealing responses in BALB/c mice infected with Leishmania major. Th2 cytokines IL-4 and IL-13 are known susceptibility...

Deletion of IL-4Rά on CD4 T Cells Renders BALB/c Mice Resistant to Leishmania major Infection (2007)

Radwanska, M., Cutler, A.J., Hoving, J.C., Magez, S., Holscher, C., Bohms, A., ...

Effector responses induced by polarized CD4þ T helper 2 (Th2) cells drive nonhealing responses in BALB/c mice infected with Leishmania major. Th2 cytokines IL-4 and IL-13 are known susceptibility...

Deletion of IL-4Rά on CD4 T Cells Renders BALB/c Mice Resistant to Leishmania major Infection (2007)

Radwanska, M., Cutler, A.J., Hoving, J.C., Magez, S., Holscher, C., Bohms, A., ...

Effector responses induced by polarized CD4þ T helper 2 (Th2) cells drive nonhealing responses in BALB/c mice infected with Leishmania major. Th2 cytokines IL-4 and IL-13 are known susceptibility...

Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes (2007)

Semballa, S., Okomo-Assoumou, M. C., Holzmuller, P., Büscher, P., Magez, S., Lemesre, J. L., ...

Antibodies (Ab) directed against a tryptophan-like epitope (WE) were previously detected in patients with human African trypanosomiasis (HAT). We investigated whether or not these Ab resulted from...

A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology (2007)

Stijlemans, B., Baral, T. N., Guilliams, M., Brys, L., Korf, J., Drennan, M., ...

The GPI-anchored trypanosome variant surface glycoprotein (VSG) triggers macrophages to produce TNF, involved in trypanosomiasis-associated inflammation and the clinical manifestation of sleeping...

Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment (2006)

Caljon, G., Sternberg, J. M., Coosemans, M., De Baetselier, P., Magez, S.

Tsetse flies (Glossina sp.) are blood-feeding dipteran insects that transmit African trypanosomes, parasites that are responsible for human sleeping sickness and veterinary infections. Increasing...

Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response (2006)

Caljon, G., Stijlemans, B., Coosemans, M., De Baetselier, P., Magez, S.

Tsetse flies (Glossina sp.) are the vectors that transmit African trypanosomes, protozoan parasites that cause human sleeping sickness and veterinary infections in the African continent. These...

The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent (2005)

Drennan, M. B., Stijlemans, B., Quesniaux, V. J., Barkhuizen, M., Brombacher, F., ...

The initial host response toward the extracellular parasite Trypanosoma brucei is characterized by the early release of inflammatory mediators associated with a type 1 immune response. In this study,...

The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense (2002)

Radwanska, M., Chamekh, M., Vanhamme, L., Claes, F., Magez, S., Magnus, E., ...

In the search for new diagnostic methods that would distinguish Trypanosoma brucei rhodesiense from T. b. brucei and T. b. gambiense, we have developed two polymerase chain reaction (PCR) primer...

Novel primer sequences for polymerase chain reaction -based detection of Trypanosoma brucei gambiense (2002)

Radwanska, M., Claes, F., Magez, S., Magnus, E., Perez-Morga, D., Pays, E., ...

Progress in diagnosis, treatment, and epidemiology of human African trypanosomiasis (sleeping sickness) depends on the existence of specific and sensitive diagnostic tools. Inherent shortcomings of...

Direct detection and identification of African trypanosomes by fluorescence in situ hybridization with peptide nucleic acid probes (2002)

Radwanska, M., Magez, S., Perry-O'Keefe, H., Stender, H., Coull, J., Sternberg, J. M., ...

We have developed a rapid and easy to perform fluorescence in situ hybridization test that allows specific identification of trypanosomes from the subgenus Trypanozoon, using peptide nucleic acid...

Control of Experimental Trypanosoma brucei Infections Occurs Independently of Lymphotoxin-α Induction

Magez, S., Stijlemans, B., Caljon, G., De Baetselier, P.

Trypanosome infections are marked by severe pathological features, including anemia, splenomegaly, and suppression of T-cell proliferation. We have used lymphotoxin-α-deficient (LT-α−/−) mice,...

Direct Detection and Identification of African Trypanosomes by Fluorescence In Situ Hybridization with Peptide Nucleic Acid Probes

Radwanska, M., Magez, S., Perry-O'Keefe, H., Stender, H., Coull, J., Sternberg, J. M., ...

We have developed a rapid and easy to perform fluorescence in situ hybridization test that allows specific identification of trypanosomes from the subgenus Trypanozoon, using peptide nucleic acid...

Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity.

Lucas, R, Echtenacher, B, Sablon, E, Juillard, P, Magez, S, Lou, J, ...

In this study, we investigated whether the recently identified lectin-like domain of tumor necrosis factor (TNF) is implicated in its biological activities on mammalian cells. To this end, a mouse...

Control of Experimental Trypanosoma brucei Infections Occurs Independently of Lymphotoxin-α Induction

Magez, S., Stijlemans, B., Caljon, G., De Baetselier, P.

Trypanosome infections are marked by severe pathological features, including anemia, splenomegaly, and suppression of T-cell proliferation. We have used lymphotoxin-α-deficient (LT-α−/−) mice,...

Direct Detection and Identification of African Trypanosomes by Fluorescence In Situ Hybridization with Peptide Nucleic Acid Probes

Radwanska, M., Magez, S., Perry-O'Keefe, H., Stender, H., Coull, J., Sternberg, J. M., ...

We have developed a rapid and easy to perform fluorescence in situ hybridization test that allows specific identification of trypanosomes from the subgenus Trypanozoon, using peptide nucleic acid...

Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity.

Lucas, R, Echtenacher, B, Sablon, E, Juillard, P, Magez, S, Lou, J, ...

In this study, we investigated whether the recently identified lectin-like domain of tumor necrosis factor (TNF) is implicated in its biological activities on mammalian cells. To this end, a mouse...