Labaied, Mehdi, Harupa, Anke, Dumpit, Ronald F., Coppens, Isabelle, Mikolajczak, Sebastian A., Kappe, Stefan H. I.
Malaria infection starts when sporozoites are transmitted to the mammalian host during a mosquito bite. Sporozoites enter the blood circulation, reach the liver, and infect hepatocytes. The formation...
The Modulation of CD40 Ligand Signaling by Transmembrane CD28 Splice Variant in Human T Cells
Mikolajczak, Sebastian A., Ma, Bruce Y., Yoshida, Tetsuya, Yoshida, Ryoko, Kelvin, David J., Ochi, Atsuo
The role of CD40 ligand (CD40L)/CD40 signaling in T cell–dependent B cell differentiation and maturation has been amply documented. The mechanism of CD40 signaling in B cells has been well...
Aly, Ahmed S I, Mikolajczak, Sebastian A, Rivera, Hilda Silva, Camargo, Nelly, Jacobs-Lorena, Vanessa, Labaied, Mehdi, ...
Malaria parasite sporozoites prepare for transmission to a mammalian host by upregulation of UIS (Upregulated in Infectious Sporozoites) genes. A number of UIS gene products are essential for the...
Mikolajczak, Sebastian A., Silva-Rivera, Hilda, Peng, Xinxia, Tarun, Alice S., Camargo, Nelly, Jacobs-Lorena, Vanessa, ...
The malaria parasite sporozoite transmission stage develops and differentiates within parasite oocysts on the Anopheles mosquito midgut. Successful inoculation of the parasite into a mammalian host...
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
VanBuskirk, Kelley M., O'Neill, Matthew T., De La Vega, Patricia, Maier, Alexander G., Krzych, Urszula, Williams, Jack, ...
Falciparum malaria is initiated when Anopheles mosquitoes transmit the Plasmodium sporozoite stage during a blood meal. Irradiated sporozoites confer sterile protection against subsequent malaria...