MACAT- MicroArray Chromosome Analysis Tool (2009)
Max Planck, Benjamin Georgi, Stefan Roepcke
Nr. 2004/02 By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving...
Zhang, Jing, Vingron, Martin, Roepcke, Stefan
Abstract Background More than two thirds of the highly expressed ribosomal protein (RP) genes in Saccharomyces cerevisiae contain introns, which is in sharp contrast to the genome-wide five percent...
BIOINFORMATICS APPLICATIONS NOTE Gene expression MACAT—microarray chromosome analysis tool (2008)
Joern Toedling, Sebastian Schmeier, Matthias Heinig, Benjamin Georgi, Stefan Roepcke
Summary: By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable...
Inferring differentiation pathways from gene expression (2008)
Costa, Ivan G., Roepcke, Stefan, Hafemeister, Christoph, Schliep, Alexander
MOTIVATION: The regulation of proliferation and differentiation of embryonic and adult stem cells into mature cells is central to developmental biology. Gene expression measured in distinguishable...
Winter, Jennifer, Roepcke, Stefan, Krause, Sven, Müller, Eva-Christina, Otto, Albrecht, Vingron, Martin, ...
Eph receptors are the largest family of receptor tyrosine kinases. Together with their ligands, the ephrins, they fulfill multiple biological functions. Aberrant expression of Ephs/ephrins leading to...
Inferring differentiation pathways from gene expression (2008)
Costa, Ivan G., Roepcke, Stefan, Hafemeister, Christoph, Schliep, Alexander
Motivation: The regulation of proliferation and differentiation of embryonic and adult stem cells into mature cells is central to developmental biology. Gene expression measured in distinguishable...
Staub, Eike, Groene, Joern, Heinze, Maya, Mennerich, Detlev, Roepcke, Stefan, Klaman, Irina, ...
Abstract Colorectal tumors have characteristic genome-wide expression patterns that allow their distinction from normal colon epithelia and facilitate clinical prognosis. The expression heterogeneity...
Winter, Jennifer, Kunath, Melanie, Roepcke, Stefan, Krause, Sven, Schneider, Rainer, Schweiger, Susann
Abstract Background Mutations in the X-linked MID1 gene are responsible for Opitz G/BBB syndrome, a malformation disorder of developing midline structures. Previous Northern blot analyses revealed...
Gene expression trees in lymphoid development (2007)
Costa, Ivan G, Roepcke, Stefan, Schliep, Alexander
Abstract Background The regulatory processes that govern cell proliferation and differentiation are central to developmental biology. Particularly well studied in this respect is the lymphoid system...
Winter, Jennifer, Kunath, Melanie, Roepcke, Stefan, Krause, Sven, Schneider, Rainer, Schweiger, Susann
Background Mutations in the X-linked MID1 gene are responsible for Opitz G/BBB syndrome, a malformation disorder of developing midline structures. Previous Northern blot analyses revealed the...
Gene expression trees in lymphoid development. (2007)
Costa, Ivan G ., Roepcke, Stefan, Schliep, Alexander
Background: The regulatory processes that govern cell proliferation and differentiation are central to developmental biology. Particularly well studied in this respect is the lymphoid system due to...
Groene, Joern, Mansmann, Ulrich, Meister, Reinhard, Staub, Eike, Roepcke, Stefan, Heinze, Maya, ...
UICC stage II and III colorectal cancers (CRC) differ fundamentally in prognosis and therapeutic concepts. To analyze differential gene expression between both stages and to establish a relationship...
Roepcke, Stefan, Zhi, Degui, Vingron, Martin, Arndt, Peter F.
For ribosomal protein (RP) genes the start of transcription is rigidly controlled to maintain the 5′-TOP signal on the messenger RNA. The responsible regulatory mechanism is not yet fully...
Kristiansen,Glen, Pilarsky,Christian, Wissmann,Christoph, Kaiser,Simone, Bruemmendorf,Thomas, Roepcke,Stefan, ...
In order to screen for differentially expressed genes that might be useful in diagnosis or therapy of prostate cancer we have used a custom made Affymetrix GeneChip containing 3950 cDNA fragments....
Kristiansen, Glen, Pilarsky, Christian, Wissmann, Christoph, Kaiser, Simone, Bruemmendorf, Thomas, Roepcke, Stefan, ...
In order to screen for differentially expressed genes that might be useful in diagnosis or therapy of prostate cancer we have used a custom made Affymetrix GeneChip containing 3950 cDNA fragments....
T-Reg Comparator: an analysis tool for the comparison of position weight matrices (2005)
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
MACAT--microarray chromosome analysis tool (2005)
Toedling, Joern, Schmeier, Sebastian, Heinig, Matthias, Georgi, Benjamin, Roepcke, Stefan
By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of...
MACAT—microarray chromosome analysis tool (2005)
Toedling, Joern, Schmeier, Sebastian, Heinig, Matthias, Georgi, Benjamin, Roepcke, Stefan
By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of...
T-Reg Comparator: an analysis tool for the (2005)
Stefan Roepcke, Steffen Grossmann, Sven Rahmann, Martin Vingron
comparison of position weight matrices
T-Reg Comparator: an analysis tool for the comparison of position weight matrices (2005)
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
MACAT--microarray chromosome analysis tool (2005)
Toedling, Joern, Schmeier, Sebastian, Heinig, Matthias, Georgi, Benjamin, Roepcke, Stefan
Summary: By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable...
MACAT - MicroArray chromosome analysis tool (2004)
Toedling, Joern, Schmeier, Sebastian, Heinig, Matthias, Georgi, Benjamin, Roepcke, Stefan
Summary: By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable...
MACAT - MicroArray chromosome analysis tool (2004)
Toedling, Joern, Schmeier, Sebastian, Heinig, Matthias, Georgi, Benjamin, Roepcke, Stefan
Summary: By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
Staub, Eike, Groene, Joern, Heinze, Maya, Mennerich, Detlev, Roepcke, Stefan, Klaman, Irina, ...
Colorectal tumors have characteristic genome-wide expression patterns that allow their distinction from normal colon epithelia and facilitate clinical prognosis. The expression heterogeneity within a...
Winter, Jennifer, Kunath, Melanie, Roepcke, Stefan, Krause, Sven, Schneider, Rainer, Schweiger, Susann
Winter, Jennifer, Roepcke, Stefan, Krause, Sven, Müller, Eva-Christina, Otto, Albrecht, Vingron, Martin, ...
Eph receptors are the largest family of receptor tyrosine kinases. Together with their ligands, the ephrins, they fulfill multiple biological functions. Aberrant expression of Ephs/ephrins leading to...
Sex-specific pathways in early cardiac response to pressure overload in mice
Witt, Henning, Schubert, Carola, Jaekel, Juliane, Fliegner, Daniela, Penkalla, Adam, Tiemann, Klaus, ...
Pressure overload (PO) first causes cardiac hypertrophy and then heart failure (HF), which are associated with sex differences in cardiac morphology and function. We aimed to identify genes that may...
Staub, Eike, Groene, Joern, Heinze, Maya, Mennerich, Detlev, Roepcke, Stefan, Klaman, Irina, ...
Wiskott–Aldrich syndrome (WAS) predisposes patients to leukemia and lymphoma. WAS is caused by mutations in the protein WASP which impair its interaction with the WIPF1 protein. Here, we aim to...
Inferring differentiation pathways from gene expression
Costa, Ivan G., Roepcke, Stefan, Hafemeister, Christoph, Schliep, Alexander
Motivation: The regulation of proliferation and differentiation of embryonic and adult stem cells into mature cells is central to developmental biology. Gene expression measured in distinguishable...