vom Fachbereich Mathematik der (2008)
Steffen Grossmann, Dekan Prof, Dr. J. Baumeister, Gutachter Prof, Dr. A. Wakolbinger, ...
This thesis has been motivated by the problem of assessing the statistical significance of the outcomes from sequence alignment algorithms. Finding similarities between sequences with entries from a...
Abha Singh Bais, Steffen Grossmann, Martin Vingron
Vol. 23 ECCB 2006, pages e44–e49 doi:10.1093/bioinformatics/btl305
Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration (2008)
Bauer, Sebastian, Grossmann, Steffen, Vingron, Martin, Robinson, Peter N.
Summary: The Ontologizer is a Java application that can be used to perform statistical analysis for overrepresentation of Gene Ontology (GO) terms in sets of genes or proteins derived from an...
Simultaneous alignment and annotation of cis-regulatory regions (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Motivation: Current methods that annotate conserved transcription factor binding sites in an alignment of two regulatory regions perform the alignment and annotation step separately and combine the...
Simultaneous alignment and annotation of cis-regulatory regions. (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Motivation: Current methods that annotate conserved transcription factor binding sites in an alignment of two regulatory regions perform the alignment and annotation step separately and combine the...
Incorporating evolution of transcription factor binding sites into annotated alignments. (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Identifying transcription factor binding sites (TFBSs) is essential to elucidate putative regulatory mechanisms. A common strategy is to combine cross-species conservation with single sequence TFBS...
Grossmann, Steffen, Bauer, Sebastian, Robinson, Peter N., Vingron, Martin
Motivation: High-throughput experiments such as microarray hybridizations often yield long lists of genes found to share a certain characteristic such as differential expression. Exploring Gene...
Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion (2006)
Duchniewicz, Marlena, Zemojtel, Tomasz, Kolanczyk, Mateusz, Grossmann, Steffen, Scheele, Jürgen S., Zwartkruis, Fried J. T.
Studies in tissue culture cells have demonstrated a role for the Ras-like GTPase Rap1 in the regulation of integrin-mediated cell-matrix and cadherin-mediated cell-cell contacts. To analyze the...
A new statistical model to select target sequences bound by transcription factors (2006)
Pape, Utz J., Grossmann, Steffen, Hammer, Stefanie, Sperling, Silke, Vingron, Martin
Transcription factors (TFs) play a key role in gene regulation by binding to target sequences. In silico prediction of potential binding to a sequence is a main task in computational biology....
Comparative promoter region analysis powered by CORG (2005)
Dieterich, Christoph, Grossmann, Steffen, Tanzer, Andrea, Röpcke, Stefan, Arndt, Peter F, Stadler, Peter F, ...
Abstract Background Promoters are key players in gene regulation. They receive signals from various sources (e.g. cell surface receptors) and control the level of transcription initiation, which...
Comparative promoter region analysis powered by CORG (2005)
Dieterich,Christoph, Grossmann,Steffen, Tanzer,Andrea, Röpcke,Stefan, Arndt,Peter F, Stadler,Peter F, ...
Background Promoters are key players in gene regulation. They receive signals from various sources (e.g. cell surface receptors) and control the level of transcription initiation, which largely...
Comparative promoter region analysis powered by CORG (2005)
Dieterich, Christoph, Grossmann, Steffen, Tanzer, Andrea, Röpcke, Stefan, Arndt, Peter F, Stadler, Peter F, ...
Background Promoters are key players in gene regulation. They receive signals from various sources (e.g. cell surface receptors) and control the level of transcription initiation, which largely...
Probabilistic soft interventions in Conditional Gaussian networks (2005)
Markowetz, Florian, Grossmann, Steffen, Spang, Rainer
We introduce a general concept of probabilistic interventions in Bayesian networks. This generalizes deterministic interventions, which fix nodes to certain states. We propose “pushing” variables...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices (2005)
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
T-Reg Comparator: an analysis tool for the (2005)
Stefan Roepcke, Steffen Grossmann, Sven Rahmann, Martin Vingron
comparison of position weight matrices
Probabilistic Soft Interventions in Conditional Gaussian Networks (2005)
Florian Markowetz Steen, Steffen Grossmann, Rainer Spang
We introduce a general concept of probabilistic interventions in Bayesian networks.
Comparative promoter region analysis powered by CORG (2005)
Dieterich, Christoph, Grossmann, Steffen, Tanzer, Andrea, Ropcke, Stefan, Arndt, Peter F, Stadler, Peter F, ...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices (2005)
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
Grossmann,Steffen, Yakir,Benjamin
We examine the distribution of the global maximum of an independent superadditive process with negative drift. We show that, under certain conditions, the distribution’s upper tail decays...
Grossmann, Steffen, Yakir, Benjamin
We examine the distribution of the global maximum of an independent superadditive process with negative drift. We show that, under certain conditions, the distribution's upper tail decays...
Grossmann, Steffen, Yakir, Benjamin
We examine the distribution of the global maximum of an independent superadditive process with negative drift. We show that, under certain conditions, the distribution’s upper tail decays...
Statistics of optimal sequence alignments (2003)
This thesis has been motivated by the problem of assessing the statistical significance of the outcomes from sequence alignment algorithms. Finding similarities between sequences with entries from a...
Statistics of optimal sequence alignments [Elektronische Ressource] / (2003)
Frankfurt (Main), University, Diss., 2003.
Statistics of optimal sequence alignments / (2003)
Frankfurt (Main), University, Diss., 2003 (Nicht für den Austausch).
Dresden, Techn. Univ., Diss., 2002.
Zur Gestaltung und zum Betriebsverhalten von Steckverbindungen der Elektroenergietechnik. (1988)
Dresden, Techn. Univ., Diss. A, 1988 (Nicht für den Austausch).
Comparative promoter region analysis powered by CORG
Dieterich, Christoph, Grossmann, Steffen, Tanzer, Andrea, Röpcke, Stefan, Arndt, Peter F, Stadler, Peter F, ...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion
Duchniewicz, Marlena, Zemojtel, Tomasz, Kolanczyk, Mateusz, Grossmann, Steffen, Scheele, Jürgen S., Zwartkruis, Fried J. T.
Studies in tissue culture cells have demonstrated a role for the Ras-like GTPase Rap1 in the regulation of integrin-mediated cell-matrix and cadherin-mediated cell-cell contacts. To analyze the...
Comparative promoter region analysis powered by CORG
Dieterich, Christoph, Grossmann, Steffen, Tanzer, Andrea, Röpcke, Stefan, Arndt, Peter F, Stadler, Peter F, ...
T-Reg Comparator: an analysis tool for the comparison of position weight matrices
Roepcke, Stefan, Grossmann, Steffen, Rahmann, Sven, Vingron, Martin
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position...
Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion
Duchniewicz, Marlena, Zemojtel, Tomasz, Kolanczyk, Mateusz, Grossmann, Steffen, Scheele, Jürgen S., Zwartkruis, Fried J. T.
Studies in tissue culture cells have demonstrated a role for the Ras-like GTPase Rap1 in the regulation of integrin-mediated cell-matrix and cadherin-mediated cell-cell contacts. To analyze the...
A Poisson model for gapped local alignments
Metzler, Dirk, Grossmann, Steffen, Wakolbinger, Anton
High score alignments of DNA sequences give evidence of a common ancestry or function. It is therefore natural to ask whether an observed high score could have arisen by pure chance, and to explore...