Stephan Collins

pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic {beta} cells (2008)

Zehetner, Jens, Danzer, Carsten, Collins, Stephan, Eckhardt, Katrin, Gerber, Philipp A., Ballschmieter, Pia, ...

Insulin secretion from pancreatic β cells is stimulated by glucose metabolism. However, the relative importance of metabolizing glucose via mitochondrial oxidative phosphorylation versus glycolysis...

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane. (2007)

Olofsson, Charlotta S, Collins, Stephan, Bengtsson, Martin, Eliasson, Lena, Salehi, Albert, Shimomura, Kenju, ...

Abstract is not available

Lipid infusion lowers sympathetic nervous activity and leads to increased β-cell responsiveness to glucose

Magnan, Christophe, Collins, Stephan, Berthault, Marie-France, Kassis, Nadim, Vincent, Mylène, Gilbert, Marc, ...

We investigated the possible involvement of the autonomic nervous system in the effect of a long-term elevation of plasma free fatty acid (FFA) concentration on glucose-induced insulin secretion...

Lipid infusion lowers sympathetic nervous activity and leads to increased β-cell responsiveness to glucose

Magnan, Christophe, Collins, Stephan, Berthault, Marie-France, Kassis, Nadim, Vincent, Mylène, Gilbert, Marc, ...

We investigated the possible involvement of the autonomic nervous system in the effect of a long-term elevation of plasma free fatty acid (FFA) concentration on glucose-induced insulin secretion...

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes

Girard, Christophe A., Wunderlich, F. Thomas, Shimomura, Kenju, Collins, Stephan, Kaizik, Stephan, Proks, Peter, ...

Neonatal diabetes is a rare monogenic form of diabetes that usually presents within the first six months of life. It is commonly caused by gain-of-function mutations in the genes encoding the Kir6.2...

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

Sumara, Grzegorz, Formentini, Ivan, Collins, Stephan, Sumara, Izabela, Windak, Renata, Bodenmiller, Bernd, ...

Dysfunction and loss of insulin-producing pancreatic β cells represent hallmarks of diabetes mellitus. Here, we show that mice lacking the mitogen-activated protein kinase (MAPK) p38δ display...

pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic β cells

Zehetner, Jens, Danzer, Carsten, Collins, Stephan, Eckhardt, Katrin, Gerber, Philipp A., Ballschmieter, Pia, ...

Insulin secretion from pancreatic β cells is stimulated by glucose metabolism. However, the relative importance of metabolizing glucose via mitochondrial oxidative phosphorylation versus glycolysis...

miR-375 maintains normal pancreatic α- and β-cell mass

Poy, Matthew N., Hausser, Jean, Trajkovski, Mirko, Braun, Matthias, Collins, Stephan, Rorsman, Patrik, ...

Altered growth and development of the endocrine pancreas is a frequent cause of the hyperglycemia associated with diabetes. Here we show that microRNA-375 (miR-375), which is highly expressed in...