Sue A. Moyer

Requirements for Measles Virus Induction of RANTES Chemokine in Human Astrocytoma-Derived U373 Cells

Noe, Katherine H., Cenciarelli, Cristina, Moyer, Sue A., Rota, Paul A., Shin, Moon L.

Interferons and chemokines play a critical role in regulating the host response to viral infection. Measles virus, a member of the Paramyxoviridae family, induces RANTES expression by astrocytes. We...

Dissection of Individual Functions of the Sendai Virus Phosphoprotein in Transcription

Bowman, Mary Catherine, Smallwood, Sherin, Moyer, Sue A.

The Sendai virus P protein is an essential component of the viral RNA polymerase (P-L complex) required for RNA synthesis. To identify amino acids important for P-L binding, site-directed mutagenesis...

The C-Terminal 88 Amino Acids of the Sendai Virus P Protein Have Multiple Functions Separable by Mutation

Tuckis, Jeffery, Smallwood, Sherin, Feller, Joyce A., Moyer, Sue A.

The Sendai virus P-L polymerase complex binds the NP-encapsidated nucleocapsid (NC) template through a P-NP interaction. To identify P amino acids responsible for binding we performed site-directed...

The Phosphoprotein (P) Binding Site Resides in the N Terminus of the L Polymerase Subunit of Sendai Virus

Holmes, David E., Moyer, Sue A.

Sendai virus encodes an RNA-dependent RNA polymerase which is composed of the L and P proteins. Site-directed mutagenesis of the N terminus of L has identified amino acids important for binding P....

Phosphorylation of Vesicular Stomatitis Virus In Vivo and In Vitro

Moyer, Sue A., Summers, Donald F.

The structural protein, NS, of purified vesicular stomatitis virus (VSV) is a phosphoprotein. In infected cells phosphorylated NS is found both free in the cytoplasm and as part of the viral...

Characterization of the Amino Acid Residues of Sendai Virus C Protein That Are Critically Involved in Its Interferon Antagonism and RNA Synthesis Down-Regulation

Kato, Atsushi, Cortese-Grogan, Case, Moyer, Sue A., Sugahara, Fumihiro, Sakaguchi, Takemasa, Kubota, Toru, ...

Sendai virus (SeV) encodes two accessory proteins, V and C, in the alternative reading frames in the P gene that are accessed transcriptionally (V) or translationally (C). The C protein is expressed...

A Single Amino Acid Change in the L-Polymerase Protein of Vesicular Stomatitis Virus Completely Abolishes Viral mRNA Cap Methylation

Grdzelishvili, Valery Z., Smallwood, Sherin, Tower, Dallas, Hall, Richard L., Hunt, D. Margaret, Moyer, Sue A.

The vesicular stomatitis virus (VSV) RNA polymerase synthesizes viral mRNAs with 5′-cap structures methylated at the guanine-N7 and 2′-O-adenosine positions (7mGpppAm). Previously, our laboratory...

Requirements for Measles Virus Induction of RANTES Chemokine in Human Astrocytoma-Derived U373 Cells

Noe, Katherine H., Cenciarelli, Cristina, Moyer, Sue A., Rota, Paul A., Shin, Moon L.

Interferons and chemokines play a critical role in regulating the host response to viral infection. Measles virus, a member of the Paramyxoviridae family, induces RANTES expression by astrocytes. We...

Dissection of Individual Functions of the Sendai Virus Phosphoprotein in Transcription

Bowman, Mary Catherine, Smallwood, Sherin, Moyer, Sue A.

The Sendai virus P protein is an essential component of the viral RNA polymerase (P-L complex) required for RNA synthesis. To identify amino acids important for P-L binding, site-directed mutagenesis...

The C-Terminal 88 Amino Acids of the Sendai Virus P Protein Have Multiple Functions Separable by Mutation

Tuckis, Jeffery, Smallwood, Sherin, Feller, Joyce A., Moyer, Sue A.

The Sendai virus P-L polymerase complex binds the NP-encapsidated nucleocapsid (NC) template through a P-NP interaction. To identify P amino acids responsible for binding we performed site-directed...

The Phosphoprotein (P) Binding Site Resides in the N Terminus of the L Polymerase Subunit of Sendai Virus

Holmes, David E., Moyer, Sue A.

Sendai virus encodes an RNA-dependent RNA polymerase which is composed of the L and P proteins. Site-directed mutagenesis of the N terminus of L has identified amino acids important for binding P....

Phosphorylation of Vesicular Stomatitis Virus In Vivo and In Vitro

Moyer, Sue A., Summers, Donald F.

The structural protein, NS, of purified vesicular stomatitis virus (VSV) is a phosphoprotein. In infected cells phosphorylated NS is found both free in the cytoplasm and as part of the viral...

Characterization of the Amino Acid Residues of Sendai Virus C Protein That Are Critically Involved in Its Interferon Antagonism and RNA Synthesis Down-Regulation

Kato, Atsushi, Cortese-Grogan, Case, Moyer, Sue A., Sugahara, Fumihiro, Sakaguchi, Takemasa, Kubota, Toru, ...

Sendai virus (SeV) encodes two accessory proteins, V and C, in the alternative reading frames in the P gene that are accessed transcriptionally (V) or translationally (C). The C protein is expressed...

A Single Amino Acid Change in the L-Polymerase Protein of Vesicular Stomatitis Virus Completely Abolishes Viral mRNA Cap Methylation

Grdzelishvili, Valery Z., Smallwood, Sherin, Tower, Dallas, Hall, Richard L., Hunt, D. Margaret, Moyer, Sue A.

The vesicular stomatitis virus (VSV) RNA polymerase synthesizes viral mRNAs with 5′-cap structures methylated at the guanine-N7 and 2′-O-adenosine positions (7mGpppAm). Previously, our laboratory...

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

Bennett, Richard L., Blalock, William L., Abtahi, Dean M., Pan, Yu, Moyer, Sue A., May, W. Stratford

While the interferon (IFN)–inducible double-stranded RNA (dsRNA)–dependent protein kinase PKR is reported to initiate apoptosis in some instances, the mechanism by which diverse stress stimuli...