Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains (2009)
Obermeier, MJ, Berg, T, Sichtig, N, Braun, P, Däumer, MP, Walter, H, ...
No abstract available.
Small-molecule inhibitors of cancer-relevant protein-protein interactions (2008)
Kiessling, A., Schust, J., Müller, J., Sperl, B., Reindl, W., Hollis, A., ...
A synthesis of atmospheric mercury depletion event chemistry in the atmosphere and snow (2008)
Steffen, A., Douglas, T., Amyot, M., Ariya, P., Aspmo, K., Berg, T., ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
A synthesis of atmospheric mercury depletion event chemistry in the atmosphere and snow (2008)
Steffen, A., Douglas, T., Amyot, M., Ariya, P., Aspmo, K., Berg, T., ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
A synthesis of atmospheric mercury depletion event chemistry in the atmosphere and snow (2008)
Steffen, A., Douglas, T., Amyot, M., Ariya, P., Aspmo, K., Berg, T., ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
Berg, T., Marosits, E., Maul, J., Nagel, P., Ott, U., Schertz, F., ...
Berg, T., Marosits, E., Maul, J., Nagel, P., Ott, U., Schertz, F., ...
A synthesis of atmospheric mercury depletion event chemistry in the atmosphere and snow (2008)
A. Steffen, T. Douglas, M. Amyot, P. Ariya, K. Aspmo, T. Berg, ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
Evidence for quantum confinement in lognormal size distributed nanodiamonds. (2008)
Berg, T., Marosits, E., Maul, J., Nagel, P., Ott, U., Schertz, F., ...
72.Jahrestagung der Deutschen Physikalischen Gesellschaft und DPG Frühjahrstagung des Arbeitskreises Festkörperphysik, Fachverband Oberflächenphysik, Berlin, 25.-29.Februar 2008
Berg, T., Marosits, E., Maul, J., Nagel, P., Ott, U., Schertz, F., ...
Journal of Applied Physics, 104(2008) S.064303/1-5
Long-range transport of air pollution into the Arctic (2007)
Stohl, A., Berg, T., Breivik, K., Burkhardt, J.F., Eckhardt, S., Fjæraa, A., ...
This paper presents an overview of air pollution transport into the Arctic. The major transport processes will be highlighted, as well as their seasonal, interannual, and spatial variability. The...
J. Sommar, I. Wängberg, T. Berg, K. Gårdfeldt, J. Munthe, A. Richter, ...
Mercury in different environmental compartments has been measured at Ny-Ålesund (78°54' N, 11°53' E) during an intensive campaign, 17 April to 14 May 2002. Time-resolved...
A. Stohl, T. Berg, J. F. Burkhart, A. M. Fjǽraa, C. Forster, A. Herber, ...
In spring 2006, the European Arctic was abnormally warm, setting new historical temperature records. During this warm period, smoke from agricultural fires in Eastern Europe intruded into the...
Stohl, A., Berg, T., Burkhart, J. F., Fj?raa, A. M., Forster, C., Herber, A., ...
In spring 2006, the European Arctic was abnormally warm, setting new historical temperature records. During this warm period, smoke from agricultural fires in Eastern Europe intruded into the...
Sommar, J., Wängberg, I., Berg, T., Gårdfeldt, K., Munthe, J., Richter, A., ...
Mercury in different environmental compartments has been measured at Ny-Ålesund (78°54' N, 11°53' E) during an intensive campaign, 17 April to 14 May 2002. Time-resolved speciated determination of...
Stohl, A., Berg, T., Burkhart, J. F., Fj?raa, A. M., Forster, C., Herber, A., ...
In spring 2006, the European Arctic was abnormally warm, setting new historical temperature records. During this warm period, smoke from agricultural fires in Eastern Europe intruded into the...
Sommar, J., Wängberg, I., Berg, T., Gårdfeldt, K., Munthe, J., Richter, A., ...
Mercury in different environmental compartments has been measured at Ny-Ålesund (78°54' N, 11°53' E) during an intensive campaign, 17 April to 14 May 2002. Time-resolved speciated determination of...
Steffen, A., Douglas, T., Amyot, M., Ariya, P., Aspmo, K., Berg, T., ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
Steffen, A., Douglas, T., Amyot, M., Ariya, P., Aspmo, K., Berg, T., ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
A. Steffen, T. Douglas, M. Amyot, P. Ariya, K. Aspmo, T. Berg, ...
It was discovered in 1995 that, during the spring time, unexpectedly low concentrations of gaseous elemental mercury (GEM) occurred in the Arctic air. This was surprising for a pollutant known to...
Enzyme replacement therapy in alpha-mannosidosis guinea-pigs (2006)
Crawley, A. C., King, B., Berg, T., Meikle, P. J., Hopwood, J. J.
Dataset issues in object recognition (2006)
Ponce, Jean, Berg, T., Everingham, Mark, Forsyth, D., Hebert, Martial, Lazebnik, S., ...
Appropriate datasets are required at all stages of object recognition research, including learning visual models of object and scene categories, detecting and localizing instances of these models in...
Enzyme replacement therapy in alpha-mannosidosis guinea-pigs (2006)
Crawley, A. C., King, B., Berg, T., Meikle, P. J., Hopwood, J. J.
Stohl, A., Berg, T., Burkhart, J. F., Fjæraa, A. M., Forster, C., Herber, A., ...
In spring 2006, the European Arctic was abnormally warm, setting new historical temperature records. During this warm period, smoke from agricultural fires in Eastern Europe intruded into the...
Stohl, A., Berg, T., Burkhart, J. F., Fjæraa, A. M., Forster, C., Herber, A., ...
In spring 2006, the European Arctic was abnormally warm, setting new historical temperature records. During this warm period, smoke from agricultural fires in Eastern Europe intruded into the...
Nondestructive full-field imaging XANES-PEEM analysis of cosmic grains (2006)
Bernhard, P., Maul, J., Berg, T., Wegelin, F., Ott, U., Sudek, C., ...
Characterization of an Fc{gamma}RI-binding peptide selected by phage display (2006)
Berntzen, G., Brekke, O. H., Mousavi, S. A., Andersen, J. T., Michaelsen, T. E., Berg, T., ...
The high-affinity IgG receptor, Fcγ receptor I (FcγRI), is expressed exclusively on myeloid cells, and there is a great interest in the targeting of vaccine antigens to FcγRI using anti-human...
Characterization of an Fc{gamma}RI-binding peptide selected by phage display (2006)
Berntzen, G., Brekke, O.H., Mousavi, S.A., Andersen, J.T., Michaelsen, T.E., Berg, T., ...
The high-affinity IgG receptor, Fcγ receptor I (FcγRI), is expressed exclusively on myeloid cells, and there is a great interest in the targeting of vaccine antigens to FcγRI using anti-human...
Berg, T., Maul, J., Erdmann, N., Bernhard, P., Schuppler, S., Nagel, P., ...
Analytical and Bioanalytical Chemistry, 386(2006) S.119-24
Kresse, W., Minnen, J., Berg, T.
DE1004013865 A UPAB: 20051117 NOVELTY - A computer display is made up of a tiled array of individual screens presenting an integrated format, each tile being driven by a single projector. The tiled...
Beerenwinkel, N., Sing, T., Lengauer, T., Rahnenfuhrer, J., Roomp, K., Savenkov, I., ...
The development of drug resistance is a major obstacle to successful treatment of HIV infection. The extraordinary replication dynamics of HIV facilitates its escape from selective pressure exerted...
Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B (2005)
Lau, GK, Piratvisuth, T, Luo, KX, Marcellin, P, Thongsawat, S, Cooksley, G, ...
BACKGROUND: Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the efficacy and safety of pegylated interferon alfa plus lamivudine,...
Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B (2005)
Lau, GK, Piratvisuth, T, Luo, KX, Marcellin, P, Thongsawat, S, Cooksley, G, ...
BACKGROUND: Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the efficacy and safety of pegylated interferon alfa plus lamivudine,...
Sommar, J., Wängberg, I., Berg, T., Gårdfeldt, K., Munthe, J., Richter, A., ...
Mercury in different environmental compartments has been measured at Ny-Ålesund (78°54? N, 11°53? E) during an intensive campaign, 17 April to 14 May 2002. Time-resolved speciated determination of...
Sommar, J., Wängberg, I., Berg, T., Gårdfeldt, K., Munthe, J., Richter, A., ...
Mercury in different environmental compartments has been measured at Ny-Ålesund (78°54? N, 11°53? E) during an intensive campaign, 17 April to 14 May 2002. Time-resolved speciated determination of...
Worldwide trend of atmospheric mercury since 1977 (2003)
Slemr, F., Brunke, E. G., Ebinghaus, R., Temme, C., Munthe, J., Wängberg, I., ...
Berg, T., Waters, O., Singh, J., Lev, M.
Thesis (M.S.)--Mercy College, 2003.
Future developments and challenges for IP over WDM network deployment (2003)
Ackaert, Ann, Colle, Didier, Demeester, Piet, ERASME, D, GUIORGUIEV, E, Lagasse, Paul, ...
Ebinghaus, R., Jennings, S.G., Schroeder, W.H., Berg, T., Donaghy, T., Guentzel, J., ...
Eleven laboratories from North America and Europe met at Mace Head, Ireland for the period 11-15 September 1995 for the first international field intercomparison of measurement techniques for...
Nilssen, O, Berg, T, Riise, HM, Ramachandran, U, Evjen, G, Hansen, GM, ...
Senoo, H, Smeland, S, Malaba, L, Bjerknes, T, Stang, E, Roos, N, ...
Rat liver stellate cells were cocultured with HepG2 human hepatoma cells, which are known to synthesize and secrete retinol-binding protein (RBP). Transfer of human RBP from HepG2 cells to stellate...
Blomhoff, R, Berg, T, Norum, K R
Newly absorbed chylomicron remnant retinyl ester is endocytosed by parenchymal liver cells, and retinol is subsequently transferred to perisinusoidal stellate cells in liver. In the present study we...
Blomhoff, R, Helgerud, P, Rasmussen, M, Berg, T, Norum, K R
We have studied hepatic uptake of chylomicron retinyl ester. Chylomicrons were obtained from intestinal lymph of rats that were given retinol in groundnut oil by intraduodenal injection. When lymph...
Tolleshaug, H, Skjelkvåle, R, Berg, T
Binding of enterotoxin from Clostridium perfringens type A was studied in suspensions of parenchymal and nonparenchymal cells from rat liver. In hepatocytes, 1.5 X 10(6) specific binding sites per...
Berg, T, Wassdal, I, Mindroiu, T, Sletten, K, Scicli, G, Carretero, O A, ...
T-kininogen, the major kininogen in rat plasma, releases Ile-Ser-bradykinin (T-kinin) when incubated with trypsin, but is not a substrate for tissue kallikrein. Enzymes able to release T-kinins from...
Characterization of a new kallikrein-like enzyme (KLP-S3) of the rat submandibular gland.
Berg, T, Schøyen, H, Wassdal, I, Hull, R, Gerskowitch, V P, Toft, K
The submandibular gland of the rat contains several enzymes belonging to the kallikrein family. These include tissue kallikrein, antigen gamma (T-kininogenase), esterase B and tonin. In the present...
Stang, E, Krause, J, Seydel, W, Berg, T, Roos, N
Endocytosis of tissue-type plasminogen activator (t-PA) by different types of rat liver cells was studied in immunocytochemically labelled cryosections as well as in biochemical experiments. For...
Kindberg, G M, Magnusson, S, Berg, T, Smedsrød, B
1. The uptake of ovalbumin (OVA) in rat liver parenchymal cells (PC) and non-parenchymal cells was studied in vivo and in vitro in order to compare the cellular expression of glycoprotein receptors...
Intracellular transport of endocytosed proteins in rat liver endothelial cells.
Kindberg, G M, Stang, E, Andersen, K J, Roos, N, Berg, T
1. Receptor-mediated endocytosis of mannose-terminated glycoproteins in rat liver endothelial cells has been followed by means of subcellular fractionation and by immunocytochemical labelling of...
Upon intravenous injection into rats, the plant toxin ricin was rapidly cleared from the circulation by the liver. Among the different liver cell populations, most of the injected ricin associated...
Malaba, L, Kindberg, G M, Norum, K R, Berg, T, Blomhoff, R
Retinol-binding protein (RBP) was iodinated directly by radio-iodine substitution on the tyrosyl residues by the sodium hypochlorite (NaOCl) or the Enzymobead (EB) methods, or indirectly by linkage...
Stang, E, Roos, N, Schlüter, M, Berg, T, Krause, J
In the liver, tissue-type plasminogen activator (t-PA) is endocytosed by hepatic parenchymal (PC), endothelial (EC) and Kupffer (KC) cells. Although the endocytosis is receptor-mediated, it remains a...
Magnusson, S, Faerevik, I, Berg, T
After receptor-mediated endocytosis, internalized ligands may be recycled to the cell surface instead of being routed to lysosomes for degradation, a process termed retroendocytosis. We have...
A multicompartmental model of fluid-phase endocytosis in rabbit liver parenchymal cells.
Blomhoff, R, Nenseter, M S, Green, M H, Berg, T
Fluid-phase endocytosis was studied in isolated rabbit liver parenchymal cells by using 125I-poly(vinylpyrrolidone) (PVP) as a marker. First, uptake of 125I-PVP by cells was determined. Also, cells...
Nenseter, M S, Blomhoff, R, Drevon, C A, Kindberg, G M, Norum, K R, Berg, T
1. Hepatic uptake of low-density lipoprotein (LDL) in parenchymal cells and non-parenchymal cells was studied in control-fed and cholesterol-fed rabbits after intravenous injection of radioiodinated...
Isolated sinusoidal endothelial rat liver cells (EC) in suspension bound and internalized ovalbumin, a mannose-terminated glycoprotein, in a saturable manner. The binding and uptake were...
Holen, I, Gordon, P B, Strømhaug, P E, Berg, T O, Fengsrud, M, Brech, A, ...
In isolated rat hepatocytes, a radiolabelled tyramine-cellobiose conjugate of asialo-orosomucoid, 125I-TC-AOM, was rapidly taken up by receptor-mediated endocytosis and proteolytically degraded in...
Purification of enzymes of the kallikrein gene family (rK8 and rK9) from the rat prostate.
Schøyen, H, Wassdal, I, Toft, K, Almendingen, M, Berg, T
The rat kallikrein family consists of multiple closely related proteins. A method for demonstration and identification of kallikrein-like proteins has been developed based on their differences in...
Berg, T O, Strømhaug, E, Løvdal, T, Seglen, O, Berg, T
Lysosome-disrupting enzyme substrates have been used to distinguish between lysosomal and prelysosomal compartments along the endocytic pathway in isolated rat hepatocytes. The cells were incubated...
Biodistributions of air-filled albumin microspheres in rats and pigs.
Walday, P, Tolleshaug, H, Gjøen, T, Kindberg, G M, Berg, T, Skotland, T, ...
The air-filled microspheres of the ultrasound-contrast agent Albunex are unique in that the walls consist of human serum albumin molecules which have been made insoluble by sonication of the albumin...
Eskild, W, Kindberg, G M, Smedsrod, B, Blomhoff, R, Norum, K R, Berg, T
Endocytosis of formaldehyde-treated serum albumin (FSA) mediated by the scavenger receptor was studied in rat liver endothelial cells. Suspended cells had about 8000 receptors/cell, whereas cultured...
Low-density-lipoprotein receptors in different rabbit liver cells.
Nenseter, M S, Myklebost, O, Blomhoff, R, Drevon, C A, Nilsson, A, Norum, K R, ...
Receptor-dependent uptake mechanisms for low-density lipoprotein (LDL) were studied in rabbit liver parenchymal and non-parenchymal cells. Hybridization studies with a cDNA probe revealed that mRNA...
Tolleshaug, H, Berg, T, Blomhoff, R
Even though most of the hepatic binding capacity for mannose-terminated glycoproteins has previously been shown to reside in the hepatocytes (not in the non-parenchymal cells), detailed evidence for...
Rustan, A C, Nossen, J O, Berg, T, Drevon, C A
Primary cultures of rat hepatocytes were used to study secretion of very-low-density lipoproteins and metabolism of asialofetuin. The ionophore monensin inhibited both secretion of very-low-density...
Retinol esterification in cultured rat liver cells.
Drevon, C A, Blomhoff, R, Rasmussen, M, Kindberg, G M, Berg, T, Norum, K R
Retinol esterification was examined in cultured hepatocytes and stellate cells from the rat. Esterification of [3H]retinol was linear for 2 h in both cell types. By increasing the concentration of...
Endocytosis of formaldehyde-treated serum albumin via scavenger pathway in liver endothelial cells.
Blomhoff, R, Eskild, W, Berg, T
Denatured or modified proteins (including albumin and low-density lipoprotein) are catabolized in vitro via scavenger receptors. We have studied the distribution of formaldehyde-denatured albumin in...
Tolleshaug, H, Abdelnour, M, Berg, T
1. The binding of 125I-labelled concanavalin A to isolated rat hepatocytes was studied at temperatures between 4 degrees C and 37 degrees C. At the latter temperature, concentrations of concanavalin...
Berg, T, Tollersrud, O K, Walkley, S U, Siegel, D, Nilssen, O
alpha-Mannosidosis is a lysosomal storage disorder that is caused by the deficiency of lysosomal alpha-mannosidase. Feline alpha-mannosidosis is a well-characterized animal model used for studying...
Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells.
Kjeken, R, Mousavi, S A, Brech, A, Griffiths, G, Berg, T
Liver endothelial cells (LECs) play an important homoeostatic role by removing potentially harmful macromolecules from blood. The extremely efficient endocytosis in LECs makes these cells an...
Magnusson, S, Berg, T, Turpin, E, Frénoy, J P
We have investigated the interactions of the plant toxin ricin with sinusoidal endothelial rat liver cells (EC). In these cells, ricin can be bound and internalized via either cell surface galactosyl...
Spectrum of mutations in alpha-mannosidosis.
Berg, T, Riise, H M, Hansen, G M, Malm, D, Tranebjaerg, L, Tollersrud, O K, ...
alpha-Mannosidosis is an autosomal recessive disorder caused by deficiency of lysosomal alpha-mannosidase (LAMAN). The resulting intracellular accumulation of mannose-containing oligosaccharides...
Senoo, H, Smeland, S, Malaba, L, Bjerknes, T, Stang, E, Roos, N, ...
Rat liver stellate cells were cocultured with HepG2 human hepatoma cells, which are known to synthesize and secrete retinol-binding protein (RBP). Transfer of human RBP from HepG2 cells to stellate...
Blomhoff, R, Berg, T, Norum, K R
Newly absorbed chylomicron remnant retinyl ester is endocytosed by parenchymal liver cells, and retinol is subsequently transferred to perisinusoidal stellate cells in liver. In the present study we...
Blomhoff, R, Helgerud, P, Rasmussen, M, Berg, T, Norum, K R
We have studied hepatic uptake of chylomicron retinyl ester. Chylomicrons were obtained from intestinal lymph of rats that were given retinol in groundnut oil by intraduodenal injection. When lymph...
Tolleshaug, H, Skjelkvåle, R, Berg, T
Binding of enterotoxin from Clostridium perfringens type A was studied in suspensions of parenchymal and nonparenchymal cells from rat liver. In hepatocytes, 1.5 X 10(6) specific binding sites per...
Berg, T, Wassdal, I, Mindroiu, T, Sletten, K, Scicli, G, Carretero, O A, ...
T-kininogen, the major kininogen in rat plasma, releases Ile-Ser-bradykinin (T-kinin) when incubated with trypsin, but is not a substrate for tissue kallikrein. Enzymes able to release T-kinins from...
Characterization of a new kallikrein-like enzyme (KLP-S3) of the rat submandibular gland.
Berg, T, Schøyen, H, Wassdal, I, Hull, R, Gerskowitch, V P, Toft, K
The submandibular gland of the rat contains several enzymes belonging to the kallikrein family. These include tissue kallikrein, antigen gamma (T-kininogenase), esterase B and tonin. In the present...
Stang, E, Krause, J, Seydel, W, Berg, T, Roos, N
Endocytosis of tissue-type plasminogen activator (t-PA) by different types of rat liver cells was studied in immunocytochemically labelled cryosections as well as in biochemical experiments. For...
Kindberg, G M, Magnusson, S, Berg, T, Smedsrød, B
1. The uptake of ovalbumin (OVA) in rat liver parenchymal cells (PC) and non-parenchymal cells was studied in vivo and in vitro in order to compare the cellular expression of glycoprotein receptors...
Intracellular transport of endocytosed proteins in rat liver endothelial cells.
Kindberg, G M, Stang, E, Andersen, K J, Roos, N, Berg, T
1. Receptor-mediated endocytosis of mannose-terminated glycoproteins in rat liver endothelial cells has been followed by means of subcellular fractionation and by immunocytochemical labelling of...
Upon intravenous injection into rats, the plant toxin ricin was rapidly cleared from the circulation by the liver. Among the different liver cell populations, most of the injected ricin associated...
Malaba, L, Kindberg, G M, Norum, K R, Berg, T, Blomhoff, R
Retinol-binding protein (RBP) was iodinated directly by radio-iodine substitution on the tyrosyl residues by the sodium hypochlorite (NaOCl) or the Enzymobead (EB) methods, or indirectly by linkage...
Stang, E, Roos, N, Schlüter, M, Berg, T, Krause, J
In the liver, tissue-type plasminogen activator (t-PA) is endocytosed by hepatic parenchymal (PC), endothelial (EC) and Kupffer (KC) cells. Although the endocytosis is receptor-mediated, it remains a...
Magnusson, S, Faerevik, I, Berg, T
After receptor-mediated endocytosis, internalized ligands may be recycled to the cell surface instead of being routed to lysosomes for degradation, a process termed retroendocytosis. We have...
A multicompartmental model of fluid-phase endocytosis in rabbit liver parenchymal cells.
Blomhoff, R, Nenseter, M S, Green, M H, Berg, T
Fluid-phase endocytosis was studied in isolated rabbit liver parenchymal cells by using 125I-poly(vinylpyrrolidone) (PVP) as a marker. First, uptake of 125I-PVP by cells was determined. Also, cells...
Nenseter, M S, Blomhoff, R, Drevon, C A, Kindberg, G M, Norum, K R, Berg, T
1. Hepatic uptake of low-density lipoprotein (LDL) in parenchymal cells and non-parenchymal cells was studied in control-fed and cholesterol-fed rabbits after intravenous injection of radioiodinated...
Isolated sinusoidal endothelial rat liver cells (EC) in suspension bound and internalized ovalbumin, a mannose-terminated glycoprotein, in a saturable manner. The binding and uptake were...
Holen, I, Gordon, P B, Strømhaug, P E, Berg, T O, Fengsrud, M, Brech, A, ...
In isolated rat hepatocytes, a radiolabelled tyramine-cellobiose conjugate of asialo-orosomucoid, 125I-TC-AOM, was rapidly taken up by receptor-mediated endocytosis and proteolytically degraded in...
Purification of enzymes of the kallikrein gene family (rK8 and rK9) from the rat prostate.
Schøyen, H, Wassdal, I, Toft, K, Almendingen, M, Berg, T
The rat kallikrein family consists of multiple closely related proteins. A method for demonstration and identification of kallikrein-like proteins has been developed based on their differences in...
Berg, T O, Strømhaug, E, Løvdal, T, Seglen, O, Berg, T
Lysosome-disrupting enzyme substrates have been used to distinguish between lysosomal and prelysosomal compartments along the endocytic pathway in isolated rat hepatocytes. The cells were incubated...
Biodistributions of air-filled albumin microspheres in rats and pigs.
Walday, P, Tolleshaug, H, Gjøen, T, Kindberg, G M, Berg, T, Skotland, T, ...
The air-filled microspheres of the ultrasound-contrast agent Albunex are unique in that the walls consist of human serum albumin molecules which have been made insoluble by sonication of the albumin...
Eskild, W, Kindberg, G M, Smedsrod, B, Blomhoff, R, Norum, K R, Berg, T
Endocytosis of formaldehyde-treated serum albumin (FSA) mediated by the scavenger receptor was studied in rat liver endothelial cells. Suspended cells had about 8000 receptors/cell, whereas cultured...
Low-density-lipoprotein receptors in different rabbit liver cells.
Nenseter, M S, Myklebost, O, Blomhoff, R, Drevon, C A, Nilsson, A, Norum, K R, ...
Receptor-dependent uptake mechanisms for low-density lipoprotein (LDL) were studied in rabbit liver parenchymal and non-parenchymal cells. Hybridization studies with a cDNA probe revealed that mRNA...
Tolleshaug, H, Berg, T, Blomhoff, R
Even though most of the hepatic binding capacity for mannose-terminated glycoproteins has previously been shown to reside in the hepatocytes (not in the non-parenchymal cells), detailed evidence for...
Rustan, A C, Nossen, J O, Berg, T, Drevon, C A
Primary cultures of rat hepatocytes were used to study secretion of very-low-density lipoproteins and metabolism of asialofetuin. The ionophore monensin inhibited both secretion of very-low-density...
Magnusson, S, Berg, T, Turpin, E, Frénoy, J P
We have investigated the interactions of the plant toxin ricin with sinusoidal endothelial rat liver cells (EC). In these cells, ricin can be bound and internalized via either cell surface galactosyl...
Retinol esterification in cultured rat liver cells.
Drevon, C A, Blomhoff, R, Rasmussen, M, Kindberg, G M, Berg, T, Norum, K R
Retinol esterification was examined in cultured hepatocytes and stellate cells from the rat. Esterification of [3H]retinol was linear for 2 h in both cell types. By increasing the concentration of...
Endocytosis of formaldehyde-treated serum albumin via scavenger pathway in liver endothelial cells.
Blomhoff, R, Eskild, W, Berg, T
Denatured or modified proteins (including albumin and low-density lipoprotein) are catabolized in vitro via scavenger receptors. We have studied the distribution of formaldehyde-denatured albumin in...
Tolleshaug, H, Abdelnour, M, Berg, T
1. The binding of 125I-labelled concanavalin A to isolated rat hepatocytes was studied at temperatures between 4 degrees C and 37 degrees C. At the latter temperature, concentrations of concanavalin...
Berg, T, Tollersrud, O K, Walkley, S U, Siegel, D, Nilssen, O
alpha-Mannosidosis is a lysosomal storage disorder that is caused by the deficiency of lysosomal alpha-mannosidase. Feline alpha-mannosidosis is a well-characterized animal model used for studying...
Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells.
Kjeken, R, Mousavi, S A, Brech, A, Griffiths, G, Berg, T
Liver endothelial cells (LECs) play an important homoeostatic role by removing potentially harmful macromolecules from blood. The extremely efficient endocytosis in LECs makes these cells an...
Spectrum of mutations in alpha-mannosidosis.
Berg, T, Riise, H M, Hansen, G M, Malm, D, Tranebjaerg, L, Tollersrud, O K, ...
alpha-Mannosidosis is an autosomal recessive disorder caused by deficiency of lysosomal alpha-mannosidase (LAMAN). The resulting intracellular accumulation of mannose-containing oligosaccharides...
Hepatic uptake of circulating IgG immune complexes.
Skogh, T, Blomhoff, R, Eskild, W, Berg, T
IgG antibodies were found to increase the uptake of circulating dinintrophenylated human serum albumin (DNP-HSA) preparations by the nonparenchymal liver cells in rats. Highly DNP-conjugated HSA was...
Some factors influencing the serum IgE levels in atopic diseases
Johansson, S. G. O., Bennich, H., Berg, T., Högman, C.
Diagnosis of atopic diseases can sometimes present difficulties. IgE estimation in serum can obviously be of value in these cases. However, on evaluating the results consideration must be taken of...
Klein, R, Zanger, U M, Berg, T, Hopf, U, Berg, P A
Anti-liver-kidney microsome antibodies (anti-LKM) occur in autoimmune hepatitis (AIH) type II and in a subset of patients with hepatitis C. Anti-LKM1 in AIH are directed against cytochrome P4502D6...
Pascu, M, Martus, P, Höhne, M, Wiedenmann, B, Hopf, U, Schreier, E, ...
Background and aims: There is growing evidence that the response of hepatitis C virus (HCV) genotype 1b infected patients towards interferon (IFN) therapy is influenced by the number of mutations...
Bjørnstad-Ostensen, A, Berg, T
1. Nitric oxide (NO) has been suggested as the mediator of the vascular response to bradykinin. In the present study, we found that NO did not mediate the hypotensive response to bradykinin. In...
Wassdal, I., Hull, R., Gerskowitch, V. P., Berg, T.
1. rK10, a weak T-kininogenase isolated from the rat submandibular gland, is a protein belonging to the rat kallikrein family. In the present work, we have studied the biological effects of rK10 with...
1. We have, in the present work, studied the importance of the kidneys and the renal hypotensive agent, medullipin, in modulating the blood pressure (BP) response to bradykinin, as well as their...
The role of endogenous bradykinin in blood pressure homeostasis in spontaneously hypertensive rats.
Holte, H. R., Bjørnstad-Ostensen, A., Berg, T.
1. The role of endogenous bradykinin in mean arterial blood pressure (BP) homeostasis was studied in spontaneously hypertensive (SHR) and normotensive (WKY) rats by the use of a bradykinin...
Diamond-Blackfan anaemia in a girl with a de novo balanced reciprocal X;19 translocation.
Gustavsson, P, Skeppner, G, Johansson, B, Berg, T, Gordon, L, Kreuger, A, ...
A 7 year old girl is described with congenital hypoplastic anaemia (Diamond-Blackfan anaemia, DBA) and an apparently balanced reciprocal translocation, 46,XX,t(X;19)(p21;q13). The girl has associated...
Keratin 8 Y54H and G62C mutations are not associated with liver disease
Halangk, J, Berg, T, Puhl, G, Mueller, T, Nickel, R, Kage, A, ...
Woelfle, J., Berg, T., Bialek, R., Keller, K. M., Effenberger, W., Wagner, N.
AIM—To determine the frequency of GB virus C (GBV-C)/hepatitis G virus (HGV) infection before and after switch to the use of virus inactivated concentrates in haemophiliac patients infected with...
Expert opinion on the treatment of patients with chronic hepatitis C
Zeuzem, S, Berg, T, Moeller, B, Hinrichsen, H, Mauss, S, Wedemeyer, H, ...
The current preferred treatment for patients with hepatitis C virus (HCV) is combination therapy consisting of pegylated interferon alfa and ribavirin (RBV) for 24–48 weeks. Although this approach...