T. Fujita

Details der Publikationsliste

Zeitraum

1933 - 2009

Anzahl

173

Co-Autoren

Enhanced superconducting gaps in the tri-layer high-$T_c$ cuprate Bi$_2$Sr$_2$Ca$_2$Cu$_3$O$_{10+\delta}$ (2009)

Ideta, S., Takashima, K., Hashimoto, M., Yoshida, T., Fujimori, A., Anzai, H., ...

We have investigated the optimally doped tri-layer cuprate Bi$_2$Sr$_2$Ca$_2$Cu$_3$O$_{10+\delta}$ (Bi2223) by angle-resolved photoemission spectroscopy, and observed energy bands and Fermi surfaces...

Unified Semi-Classical Description of Intrinsic Spin-Hall Effect in Spintronic, Optical, and Graphene Systems (2009)

Fujita, T., Jalil, M. B. A., Tan, S. G.

A semi-classical description of the intrinsic spin-Hall effect (SHE) is presented which is relevant for a wide class of systems. A heuristic model for the SHE is developed, starting with a fully...

Unified Description of the Intrinsic Spin-Hall Effects (2009)

Fujita, T., Jalil, M. B. A., Tan, S. G.

The intrinsic spin-Hall effects (SHE) in $p$-doped semiconductors [S. Murakami et al., Science 301, 1348 (2003)] and two-dimensional electron gases with Rashba spin-orbit coupling [J. Sinova et al.,...

New Renormalization Scheme of Vacuum Polarization in QED (2009)

Fujita, T., Kanda, N., Kato, H., Kubo, H., Munakata, Y., Oshima, S., ...

We examine the vacuum polarization contribution in the renormalization scheme of QED. Normally, the quadratic divergence term is discarded under the condition that the counter term of the Lagrangian...

Lower secondary school students’ understanding of algebraic proof (2009)

Kunimune, S., Kumakura, H., Jones, K., Fujita, T.

Secondary school students are known to face a range of difficulties in learning about proof and proving in mathematics. This paper reports on a study designed to address the issue of students’...

Doping and Temperature Dependence of Raman Scattering of NdFeAsO1-xFx (x=0.0, 0.1, 0.2) Superconductor (2008)

Zhang, L., Fujita, T., Chen, F., Feng, D. L., Maekawa, S., Chen, M. W.

Raman spectra of polycrystalline NdFeAsO1-xFx (x=0.0, 0.1, 0.2) compound have been systematically investigated as functions of temperature and fluorine concentration. Scanning electron microscopic...

Studies of Current Profile Optimization and Influence of Electron Heating towards Advanced Tokamak Operation on JT-60U (2008)

S. Ide, T. Suzuki, Y. Sakamoto, H. Takenaga, T. Fujita, N. Oyama, ...

Abstract. Experimental results of studies towards steady state operation of an advanced tokamak on JT-60U are presented. Especially, issues that are related to a current profile and internal...

Unphysical Gauge Fixing in Higgs Mechanism (2008)

Fujita, T., Kusaka, A., Tsuda, K., Oshima, S.

The unitary gauge in the Higgs mechanism is to impose the condition of $\phi =\phi^\dagger $ on the Higgs fields. However, this is not the gauge fixing but simply a procedure for producing the...

Non-Abelian gauge field effects and its relevance to spinning particle dynamics in the technology of spintronics (2007)

Tan, S. G., Jalil, M. B. A., Fujita, T.

We describe formally the precession of spin vector about the k-space effective magnetic field in condensed matter system with spin orbital effects as constituting a local transformation of the...

Topological spin-Hall current in waveguided zinc-blende semiconductors with Dresselhaus spin-orbit coupling (2007)

Fujita, T., Jalil, M. B. A., Tan, S. G.

We describe an intrinsic spin-Hall effect in $n$-type bulk zinc-blende semiconductors with topological origin. When electron transport is confined to a waveguide structure, and the applied electric...

Ultra-large room-temperature compressive plasticity of a nanocrystalline metal (2007)

Pan, D., Kuwano, S., Fujita, T., Chen, M. W.

We report ultra-large room-temperature plasticity of nanocrystalline Ni subjected to uniaxial compression. Up to 200% true plastic strain is achieved with a steady flow stress of similar to 2 GPa at...

Microstructural characterization of dispersion-strengthened Cu–Ti–Al alloys obtained by reaction milling (2007)

ESPINOZA, R, PALMA, R, SEPULVEDA, A, FUENZALIDA, V, SOLORZANO, G, CRAIEVICH, A, ...

The microstructure, electrical conductivity and hot softening resistance of two alloys (G-10 and H-20), projected to attain Cu–2.5 vol.% TiC–2.5 vol.% Al2O3 nominal composition, and prepared by...

Learners’ understanding of the definitions and hierarchical classification of quadrilaterals: towards a theoretical framing (2007)

Fujita, T., Jones, K.

Defining and classifying quadrilaterals, though an established component of the school mathematics curriculum, appears to be a difficult topic for many learners. The reasons for such difficulties...

Chapter 2: Plasma confinement and transport (2007)

Doyle, E. J., Houlberg, W. A., Kamada, Y., Mukhovatov, V., Osborne, T. H., Polevoi, A., ...

The understanding and predictive capability of transport physics and plasma confinement is reviewed from the perspective of achieving reactor-scale burning plasmas in the ITER tokamak, for both core...

2005年度中等教育研究協議会 (VII. 2005年度中等教育研究協議会) (2006)

藤田, 高弘, FUJITA, T.

国立情報学研究所で電子化したコンテンツを使用している。

On a particular class of self-decomposable random variables : the durations of Bessel excursions straddling independent exponential times. (2006)

Bertoin, J., Fujita, T., Roynette, Bernard, Yor, Marc

The distributional properties of the duration of a recurrent Bessel process straddling an independent exponential time are studied in detail. Althrough our study may be considered as a particular...

On a particular class of self-decomposable random variables : the durations of Bessel excursions straddling independent exponential times. (2006)

Bertoin, J., Fujita, T., Roynette, Bernard, Yor, Marc

The distributional properties of the duration of a recurrent Bessel process straddling an independent exponential time are studied in detail. Althrough our study may be considered as a particular...

Influence of sex hormone disturbances on the internal structure of the mandible in newborn mice (2006)

Fujita, T., Ohtani, J., Shigekawa, M., Kawata, T., Kaku, M., Kohno, S., ...

It has not yet been clarified how sex hormones affect craniofacial bone development immediately after birth. The purpose of this study was to examine the effects of sex hormone deficiency on...

Developing geometrical reasoning in the classroom: learning from highly experienced teachers from China and Japan (2005)

Ding, L, Fujita, T, Jones, K

Mathematics education has been the subject of considerable international comparative research, mostly focussed on pupil achievement but also examining teaching methods, curricula, and so on. In all...

The role of intuition in geometry education: learning from the teaching practice in the early 20th century (2004)

Fujita, T., Jones, K., Yamamoto, S.

Intuition is often regarded as essential in the learning of geometry, but questions remain about how we might effectively develop students’ such skills. This paper provides some results from...

Results of the Rumphius Biohistorical Expedition to Ambon (1990). Part 12. The Asteroidea (Echinodermata) collected from Ambon, Indonesia (2004)

Fujita, T., Marsh, L.M.

During the Rumphius Biohistorical Expedition (4.xi-17.xii.1990) and some additional field trips to Ambon, a total of 26 species of asteroids were collected. Seven species were new to Ambon, and four...

Review on the progress of the LHD experiment (2004)

Motojima, O., Yamada, H., Komori, A., Watanabe, K. Y., Mutoh, T., Takeiri, Y., ...

Recent progress in the Large Helical Device (LHD) experiment during the last 2 yr is reviewed. The LHD has been extending its operational regime toward fusion-relevant conditions while taking...

Status of and prospects for advanced tokamak regimes from multi-machine comparisons using the 'International Tokamak Physics Activity' database (2004)

Litaudon, X., Barbato, E., Becoulet, A., Doyle, E. J., Fujita, T., Gohil, P., ...

Advanced tokamak regimes obtained in ASDEX Upgrade, DIII-D, FF-U, JET, JT-60U, TCV and Tore Supra experiments are assessed both in terms of their fusion performance and capability for ultimately...

Progress in Separating Plastic Materials for Recycling (2004)

G. Dodbiba, T. Fujita

In order to deal with the problems facing the plastics processing industry research, work is focused primarily on designing, developing and testing a variety of separation and sorting techniques able...

Crystallographic orientation contrast associated with Ga+ ion channelling for Fe and Cu in focused ion beam method (2004)

Yahiro, Y., Kaneko, K., Fujita, T., Horita, Z.

In this study, Cu and Fe single crystals are used to examine the change in secondary electron intensity associated with Ga+ ion channelling in a focused ion beam (FIB) system. The single...

Increased understanding of the dynamics and transport in ITB plasmas from multi-machine comparisons (2003)

Gohil, P., Kinsey, J., Parail, V., Litaudon, X., Fukuda, T., Hoang, T., ...

Our understanding of the physics of internal transport barriers (ITBs) is being furthered by analysis and comparisons of experimental data from many different tokamaks worldwide. An international...

Recent advances in the LHD experiment (2003)

Motojima, O., Ohyabu, N., Komori, A., Kaneko, O., Yamada, H., Kawahata, K., ...

In the first four years of the LHD experiment, several encouraging results have emerged, the most significant of which is that MHD stability and good transport are compatible in the inward shifted...

Pricing path-dependent options in some Black-Scholes market, from the distribution of homogeneous Brownian functionals (2003)

T. Fujita, F. Petit, M. Yor

Abstract. We give some explicit formulae for the prices of two path-dependent options which combine Brownian averages and penalizations. Because these options are based on both the maximum and local...

Separation Performance of PVC and PP Plastic Mixture Using Air Table (2003)

G. Dodbiba, A. Shibayama, T. Miyazaki, T. Fujita

The aim of the research presented in this article was to investigate separation performance of the air table when separating a binary mixture of plastics. Separation using the air table, i.e. a dry...

Electronic properties of a URhGe single crystal (2002)

Prokes, K., Tahara, T., Echizen, Y., Takabatake, T., Fujita, T., ...

Structural studies by means of powder X-ray diffraction and single-crystal neutron diffraction show that URhGe crystallizes in the orthorhombic TiNiSi-type of structure. Combined...

The Recovery and Life Cycle Assessment of Nickel Particles in A Multi-Solenoid Open-Gradient Magnetic Separator (2002)

A. Shibayama, M. Matsuda, A. Otsuki, G. Dodbiba, T. Fujita, B. Jeyadevan, ...

The recovery of 87% and the grade of 30% of Ni from nickel tip capacitors were achieved using a multi-solenoid open-gradient magnetic separator. A series of tests under varying conditions, such as...

Electrostatic Separation of the Shredded Plastic Mixtures Using A Tribo-Cyclone (2002)

G. Dodbiba, A. Shibayama, T. Miyazaki, T. Fujita

In this experimental work, artificial plastic mixture of two kinds of components (i.e. PET and PE mixture) is tribo-electrostatically separated. The mixture is charged by friction in a...

EDM operator free from Schiff's theorem (2001)

Asaga, T., Fujita, T., Hiramoto, M.

We present a generalization of Schiff's transformation of electric dipole moments (EDM) in quantum field theory. Under the unitary transformation, the time and parity violating interaction i ge/2...

Magnetic specific heat of a URhGe single crystal (2000)

Prokes, K., Echizen, Y., Takabatake, T., Fujita, T., Klaasse, J.C.P., ...

URhGe crystallizes in the orthorhombic TiNiSi-type of structure and has been studied untill now only in polycrystalline form. Here, we report on the low-temperature speci"c heat of URhGe measured on...

Superplasticity of unltrafine-grained Al-3% Mg-0.2% Sc alloy produced by equal-channel angular pressing (2000)

Fujita, T., Komura, S., Horita, Z., Langdon, T.G.

This paper describes grain refinement of an Al-3%Mg-0.2%Sc alloy using the equal-channel angular pressing(ECAP) technique at room temperature. It is shown that a grain size of 0.2.MU.m is obtained...

Human follicular dendritic cells in vitro and follicular dendritic-cell-like cells. (1997)

Tsunoda, R, Bosseloir, A, Onozaki, K, Heinen, Ernst, Miyake, K, Okamura, H, ...

Human follicular dendritic cell (FDC)-like cells (FLC) have been utilized for the in vitro analysis of germinal center reactions. However, there is no consensus whether FLC represent FDC in vitro....

The effects of sevoflurane are similar to those of isoflurane on the neuromuscular block produced by vecuronium (1994)

MORITA, T., TSUKAGOSHI, H., SUGAYA, T., YOSHIKAWA, D., FUJITA, T.

We have examined the interactions of 1 MAC of isoflurane and sevoflurane (and 66% nitrous oxide in oxygen) with vecuronium, using the EMG response of the abductor digiti minimi to...

A PRELIMINARY STUDY ON THE EFFECT OF ALPHA-INTERFERON TREATMENT ON THE JOINT INFLAMMATION AND SERUM CALCIUM IN RHEUMATOID ARTHRITIS (1992)

SHIOZAWA, S., SHIOZAWA, K., KITA, M., KISHIDA, T., FUJITA, T., IMURA, S.

A 12-week, double-blind controlled study comparing low dose α-interferon (5×105 iu, twice a week) and placebo was carried out to determine whether this drug has an immunomodulatory effect in...

IMMUNOREACTIVE CIRCULATING ALPHA-INTERFERON IS LOW IN SJOGREN'S SYNDROME (1990)

SHIOZAWA, S., SHIOZAWA, K., SHIMIZU, S., TANAKA, Y., MORIMOTO, I., YOSHIHARA, R., ...

Circulating α-interferon in plasma of 26 patients with Sjögren's syndrome was 0.069± 0.034ng/ml. a significant decrease compared with 0.119±0.051 ng/ml for age- and sex-matched healthy...

LOW-TEMPERATURE SPECIFIC HEAT OF AN ANTIFERROMAGNETIC DENSE-KONDO COMPOUND CePdIn (1988)

Satoh, K., Maeno, Y., Fujita, T., Uwatoko, Y., Fujii, H.

Specific heat of a dense-Kondo compound CePdIn was measured down to 60 mK. Two anomalies in C/T were found at 1.7 and 0.9 K, and are discussed in terms of antiferromagnetic transition and formation...

LOW-TEMPERATURE SPECIFIC HEAT OF AN ANTIFERROMAGNETIC DENSE-KONDO COMPOUND CePdIn (1988)

Satoh, K., Maeno, Y., Fujita, T., Uwatoko, Y., Fujii, H.

Specific heat of a dense-Kondo compound CePdIn was measured down to 60 mK. Two anomalies in C/T were found at 1.7 and 0.9 K, and are discussed in terms of antiferromagnetic transition and formation...

LOW-TEMPERATURE SPECIFIC HEAT OF AN ANTIFERROMAGNETIC DENSE-KONDO COMPOUND CePdIn (1988)

Satoh, K., Maeno, Y., Fujita, T., Uwatoko, Y., Fujii, H.

Specific heat of a dense-Kondo compound CePdIn was measured down to 60 mK. Two anomalies in C/T were found at 1.7 and 0.9 K, and are discussed in terms of antiferromagnetic transition and formation...

IV. TRANSPORTELECTRONIC STRUCTURE OF EUB6, TRANSPORT AND MAGNETIC PROPERTIES (1980)

Kasuya, T., Takegahara, K., Kasaya, M., Isikawa, Y., Fujita, T.

In non-magnetic R++B6, it is shown that the most common defect R++ vacancy can trap third hole creating a compensating conduction electron due to the narrow gap semiconductor character. The latter is...

IV. TRANSPORTELECTRONIC STRUCTURE OF EUB6, TRANSPORT AND MAGNETIC PROPERTIES (1980)

Kasuya, T., Takegahara, K., Kasaya, M., Isikawa, Y., Fujita, T.

In non-magnetic R++B6, it is shown that the most common defect R++ vacancy can trap third hole creating a compensating conduction electron due to the narrow gap semiconductor character. The latter is...

IV. TRANSPORTELECTRONIC STRUCTURE OF EUB6, TRANSPORT AND MAGNETIC PROPERTIES (1980)

Kasuya, T., Takegahara, K., Kasaya, M., Isikawa, Y., Fujita, T.

In non-magnetic R++B6, it is shown that the most common defect R++ vacancy can trap third hole creating a compensating conduction electron due to the narrow gap semiconductor character. The latter is...

Valence Fluctuating State in SmB6 (1979)

Kasuya, T., Takegahara, K., Fujita, T., Tanaka, T., Bannai, E.

Specific heat and transport properties are measured on good single crystals of SmB6. The specific heat experiment indicates that there is a gap of near 100 K in the 4f system leaving a very small T...

Valence Fluctuating State in SmB6 (1979)

Kasuya, T., Takegahara, K., Fujita, T., Tanaka, T., Bannai, E.

Specific heat and transport properties are measured on good single crystals of SmB6. The specific heat experiment indicates that there is a gap of near 100 K in the 4f system leaving a very small T...

Valence Fluctuating State in SmB6 (1979)

Kasuya, T., Takegahara, K., Fujita, T., Tanaka, T., Bannai, E.

Specific heat and transport properties are measured on good single crystals of SmB6. The specific heat experiment indicates that there is a gap of near 100 K in the 4f system leaving a very small T...

ATTENUATION OF THE DIURETIC EFFECT OF DOPAMINE BY DROPERIDOL IN MAN AND DOGS (1979)

GOTO, F., FUJITA, T., FUSE, Y.

The effects of dopamine 0.5–6.0 μg kg−1 min−1 on urine flow and the excretion of sodium and inorganic effect phosphate were studied in patients and dogs. In both the patients and the animals...

Preliminary Report of the 1977 Eruption of Usu Volcano (1978)

Katsui, Y., Ōba, Y., Onuma, K., Suzuki, T., Kondo, Y., Watanabe, T., ...

On August 7 (09h 12m, local time), 1977, a major eruption of dacite pumice occurred from the summit of Usu Volcano (42°32'N, 140°50'E), Hokkaido, Japan, after 32 years of dormancy since the birth...

ELECTRON SPIN RESONANCE IN FINE PARTICLES OF METALLIC LITHIUM (1977)

Fujita, T., Saiki, K., Shimizu, Y.

The relaxation of conduction electron spins in fine particles of metallic lithium was measured by an X-band spectrometer at room temperature. Those particles of diameter from about 3 000 to 100 Å...

THE PHONON SOFTENING IN METALLIC FINE PARTICLES (1977)

Ohshima, K., Fujita, T., Kuroishi, T.

The d.c. electrical resistance of films of Ag and Al fine particles was measured between 1.5 and 300 K. The enhancement of the superconducting transition temperature and the reduction of the Debye...

ELECTRON SPIN RESONANCE IN FINE PARTICLES OF METALLIC LITHIUM (1977)

Fujita, T., Saiki, K., Shimizu, Y.

The relaxation of conduction electron spins in fine particles of metallic lithium was measured by an X-band spectrometer at room temperature. Those particles of diameter from about 3 000 to 100 Å...

THE PHONON SOFTENING IN METALLIC FINE PARTICLES (1977)

Ohshima, K., Fujita, T., Kuroishi, T.

The d.c. electrical resistance of films of Ag and Al fine particles was measured between 1.5 and 300 K. The enhancement of the superconducting transition temperature and the reduction of the Debye...

ELECTRON SPIN RESONANCE IN FINE PARTICLES OF METALLIC LITHIUM (1977)

Fujita, T., Saiki, K., Shimizu, Y.

The relaxation of conduction electron spins in fine particles of metallic lithium was measured by an X-band spectrometer at room temperature. Those particles of diameter from about 3 000 to 100 Å...

THE PHONON SOFTENING IN METALLIC FINE PARTICLES (1977)

Ohshima, K., Fujita, T., Kuroishi, T.

The d.c. electrical resistance of films of Ag and Al fine particles was measured between 1.5 and 300 K. The enhancement of the superconducting transition temperature and the reduction of the Debye...

THE SUPPRESSIVE EFFECT OF HALOTHANE ON DNA SYNTHESIS OF IMMUNOCYTES (1976)

BANDOH, T., FUJITA, T.

Mice, previously immunized with sheep erythrocytes, were anaesthetized with halothane and the splenic lymphoid cells were incubated with 3H-thymidine at 1-h intervals. A biphasic response was...

Review of Current Dental Literature; Macacus fuscatus. (1933)

Fujita, T.

Editors: Aug. 1859-July 1865, J. D. White, J. H. McQuillen, G. J. Ziegler.--Aug. 1865-Dec. 1871, J. H. McQuillen, G. J. Ziegler.--Jan. 1872-May 1891, J. W. White.--July 1891-Apr. 1930, E. C. Kirk...

Immunopathological features of palatine tonsil characteristic of IgA nephropathy: IgA1 localization in follicular dendritic cells.

Kusakari, C, Nose, M, Takasaka, T, Yuasa, R, Kato, M, Miyazono, K, ...

IgA nephropathy (IgAN) is generally thought to be mediated by the glomerular deposition of circulating immune complexes containing IgA as the major antibody component. Upper respiratory infections...

Detection of tumour necrosis factor/cachectin in pleural effusion of patients with lung cancer.

Ishii, Y, Uchiyama, Y, Hasegawa, S, Kinoshita, T, Mitsui, K, Kojima, H, ...

We have found that the pleural effusion obtained from a patient with lung cancer (adenocarcinoma) has cytotoxic activity against the patient's lung cancer cells. This finding occurred in the course...

Expression of decay-accelerating factor is reduced on hyperplastic synovial lining cells in rheumatoid synovitis.

Itoh, J, Nose, M, Fujita, T, Kato, M, Ohyama, A, Kyogoku, M

Decay-accelerating factor (DAF), a membrane inhibitor of homologous complement activation, is present in synovial cells lining joint space and detected in synovial fluid. DAF is considered to protect...

IgG heavy chain allotype (Gm), a genetic marker for human chromosome 14q32, and haematopoietic malignancies.

Nakao, Y, Matsumoto, H, Tsuji, K, Miyazaki, T, Masaoka, T, Nakayama, S, ...

IgG heavy chain constant region allotypes, Gm, the genetic marker of human chromosome 14q32, are markers for susceptibility to certain diseases. We tested Gm allotypes in 365 patients with various...

Primary hepatocellular carcinoma and IgG heavy chain allotypes.

Nakao, Y, Matsumoto, H, Okubo, A, Miyazaki, T, Iwasaki, Y, Okimoto, K, ...

We studied Gm typing of serum samples from 838 donors; 177 had chronic hepatitis, 166 liver cirrhosis, 113 primary hepatocellular carcinoma, 21 alcoholic hepatitis, 18 fatty liver and 343 were...

Genetic and clinical studies of serum beta 2-microglobulin levels in haematological malignancies.

Nakao, Y, Matsumoto, H, Miyazaki, T, Watanabe, S, Masaoka, T, Takatsuki, K, ...

Sera from 244 patients with haematological malignancies were examined for beta 2-microglobulin (beta 2m) levels. There were 142 leukaemias, 32 malignant lymphomas, three immunoblastic lymphomas, two...

Complement-mediated solubilization of immune complexes in systemic lupus erythematosus.

Sakurai, T, Fujita, T, Kono, I, Kabashima, T, Yamane, K, Tamura, N, ...

The capacity of complement-mediated solubilization of immune complexes (complex releasing activity: CRA) was studied in 63 sera from eight systemic lupus erythematosus (SLE) patients. CRA in sera of...

Immunologic studies on Werner's syndrome.

Nakao, Y, Hattori, T, Takatsuki, K, Kuroda, Y, Nakaji, T, Fujiwara, Y, ...

Five patients with Werner's syndrome were studied to elucidate the relationship between the immune system and the ageing process. Three of five patients had neoplasms such as fibrosarcoma, meningioma...

IgG heavy chain allotypes (Gm) in autoimmune diseases.

Nakao, Y, Matsumoto, H, Miyazaki, T, Nishitani, H, Takatsuki, K, Kasukawa, R, ...

Serum samples from 100 patients with myasthenia gravis, 322 with Graves' disease, 113 with Hashimoto's disease, 132 with systemic lupus erythematosus (SLE), 192 with insulin-dependent juvenile...

Differences between plasma and serum complement in patients with chronic liver disease.

Inai, S, Kitamura, H, Fujita, T, Kojima, J, Nagaki, K

Of sixty patients with chronic liver disease, eight with cirrhosis or chronic hepatitis had very low serum CH50 but normal plasma CH50. The complement component profiles of these sera revealed...

Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma.

Buchan, G, Barrett, K, Fujita, T, Taniguchi, T, Maini, R, Feldmann, M

Attempts to detect immune mediators in RA synovial fluids by bioassay or radioimmunoassay have yielded conflicting results, and so we have begun to analyse the complex immunological reactions...

A sensitive radioimmunoassay for alpha-interferon: circulating alpha-interferon-like substance in the plasma of healthy individuals and rheumatoid arthritis patients.

Shiozawa, S, Chihara, K, Shiozawa, K, Fujita, T, Ikegami, H, Koyama, S, ...

A radioimmunoassay for circulating alpha-interferon (IFN alpha) has been developed using lymphoblastoid IFN alpha. The assay was specific for IFN alpha, and did not cross-react with IFN beta, IFN...

Monoclonal antibody against bacterial lipopolysaccharide cross-reacts with DNA-histone.

Sumazaki, R, Fujita, T, Kabashima, T, Nishikaku, F, Koyama, A, Shibasaki, M, ...

Monoclonal antibodies to bacterial lipopolysaccharide (LPS) were prepared by fusing spleen cells from BALB/c mice immunized with Salmonella Minnesota Re 595 LPS to the mouse myeloma cell line P3U1....

Significance of C3 nephritic factor (C3NeF) in non-hypocomplementaemic serum with membranoproliferative glomerulonephritis (MPGN).

Ohi, H, Watanabe, S, Fujita, T, Yasugi, T

C3NeF is an autoantibody of C3 convertase (C3bBb) and is often detected in the serum of hypocomplementaemic MPGN patients. Serum samples from 104 non-hypocomplementaemic MPGN patients (C3NeF) were...

Interaction of complement solubilized complexes with mouse peritoneal macrophages and their clearance and tissue uptake.

Takahashi, N, Fujita, T, Takata, Y, Tamura, N

To clarify the biological activity of complement solubilized immune complexes, we studied their interaction with mouse peritoneal macrophages. The solubilized complexes lost their binding affinity...

Role of interleukin-12 in the regulation of CD4+ T cell apoptosis in a mouse model of asthma

KODAMA, T, KURIBAYASHI, K, NAKAMURA, H, FUJITA, M, FUJITA, T, TAKEDA, K, ...

Allergic asthma, a chronic inflammatory disease of the airways, is characterized by the presence of T helper 2 cells and eosinophils in sputum, bronchoalveolar lavage, and mucosal biopsy specimens....

No strong relationship between mannan binding lectin or plasma ficolins and chemotherapy-related infections

KILPATRICK, D C, MCLINTOCK, L A, ALLAN, E K, COPLAND, M, FUJITA, T, JORDANIDES, N E, ...

Chemotherapy causes neutropenia and an increased susceptibility to infection. Recent reports indicate that mannan-binding lectin (MBL) insufficiency is associated with an increased duration of...

Elevated macrophage migration inhibitory factor (MIF) levels in the urine of patients with focal glomerular sclerosis

Matsumoto, K, Maruyama, N, Maruyama, T, Ohnishi, Y, Nonaka, S, Inoshita, A, ...

The pathogenesis of focal glomerular sclerosis (FGS) is poorly understood. Macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine released from T cells and macrophages,...

Regulation of local and metastatic host-mediated anti-tumour mechanisms by l-selectin and intercellular adhesion molecule-1

Yamada, M, Yanaba, K, Hasegawa, M, Matsushita, Y, Horikawa, M, Komura, K, ...

Malignant melanoma is often accompanied by a host response of inflammatory cell infiltration that is highly regulated by multiple adhesion molecules. To assess the role of adhesion molecules,...

Decay-accelerating factor (DAF) in stool specimens as a marker of disease activity in patients with ulcerative colitis (UC)

Inaba, T, Mizuno, M, Ohya, S, Kawada, M, Uesu, T, Nasu, J, ...

Colonic epithelial cells of patients with UC express DAF in relation to the severity of mucosal inflammation. The aim of this study was to determine whether this factor in stool could be used as a...

Cytokine-stimulated release of decay-accelerating factor (DAF; CD55) from HT-29 human intestinal epithelial cells

Nasu, J, Mizuno, M, Uesu, T, Takeuchi, K, Inaba, T, Ohya, S, ...

Expression of DAF (CD55) is enhanced on colonic epithelial cells of patients with ulcerative colitis (UC), and stool DAF concentrations are increased in patients with active disease. Cytokines are...

Effect of angiotensin-converting enzyme inhibitor YS980 on prostaglandin synthesis in rabbit kidney medulla slices.

Fujimoto, Y., Wada, K., Kaneko, M., Fujita, T.

The effect of YS980, an angiotensin-converting enzyme inhibitor, on the generation of medullary prostaglandins E2 and F2 alpha was examined. At concentrations of 0.2 mM and below, YS980 enhanced...

Effect of lipid peroxidation on p-aminohippurate transport by rat kidney cortical slices.

Fujimoto, Y., Fujita, T.

1 The effect of lipid peroxidation on p-aminohippurate transport by rat kidney slices was examined. 2 Ascorbic acid and Fe2+ promoted lipid peroxidation of rat renal cortical slices in a dose-related...

Distribution of activated complement, C3b, and its degraded fragments, iC3b/C3dg, in the colonic mucosa of ulcerative colitis (UC)

UEKI, T, MIZUNO, M, UESU, T, KISO, T, NASU, J, INABA, T, ...

The third component of complement (C3) is central to both the classical and alternative pathways in complement activation. In this study, involvement of C3 activation in the mucosal injury of UC was...

Human serum mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1): determination of levels in body fluids and identification of two forms in serum

TERAI, I, KOBAYASHI, K, MATSUSHITA, M, FUJITA, T

We developed an ELISA for human serum MASP-1, a Cls-like serine protease which is known to function in C4 and C2 activation. We then determined MASP-1 levels in 1063 sera from normal Japanese...

Surgical treatment of brain metastases of lung cancer: retrospective analysis of 89 cases.

Nakagawa, H, Miyawaki, Y, Fujita, T, Kubo, S, Tokiyoshi, K, Tsuruzono, K, ...

The records of 89 patients who underwent surgery for solitary or multiple parenchymal brain metastases of lung cancer at the Osaka Center for Adult Diseases between 1978 and 1990 were reviewed with...

Clinical, neuropathological, and molecular study in two families with spinocerebellar ataxia type 6 (SCA6)

Ishikawa, K, Watanabe, M, Yoshizawa, K, Fujita, T, Iwamoto, H, Yoshizawa, T, ...

To clarify the clinical, neuropathological, and molecular characteristics of spinocerebellar ataxia type 6 (SCA6), two unrelated Japanese families with SCA6 were studied. A clinical feature of the...

The role of C4-binding protein and {beta }1H in proteolysis of C4b and C3b

Fujita, T, Nussenzweig, V

Two forms of C4-binding protein (C4-bp) (C4-bp low, C4-bp high), which differ slightly in net charge and apparent molecular weight, as determined by SDS- PAGE, were separated by ion-exchange...

Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470).

Kusaka, M., Sudo, K., Matsutani, E., Kozai, Y., Marui, S., Fujita, T., ...

Recently, we reported the anti-angiogenic action along with anti-tumour activity of TNP-470 (AGM-1470). In this study, the effect of TNP-470 on the growth of human umbilical vein endothelial (HUVE)...

Effects of sodium n-butyrate on alpha-fetoprotein and albumin secretion in the human hepatoma cell line PLC/PRF/5.

Nakagawa, T., Nakao, Y., Matsui, T., Koizumi, T., Matsuda, S., Maeda, S., ...

The in vitro effects of sodium n-butyrate (butyrate) on the growth, morphology and secretion of alpha-fetoprotein (AFP) and albumin by the human heptoma cell line PLC/PRF/5 were studied. Butyrate...

Pharmacological effects of 5-fluorouracil microspheres on peritoneal carcinomatosis in animals.

Hagiwara, A., Takahashi, T., Sawai, K., Sakakura, C., Tsujimoto, H., Imanishi, T., ...

A new delivery formulation (5FU-MS) of 5-fluorouracil (5FU), 5FU incorporated in microspheres composed of poly(glycolide-co-lactide) matrix, has been developed for the treatment of peritoneal...

PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer

Fujita, T, Doihara, H, Kawasaki, K, Takabatake, D, Takahashi, H, Washio, K, ...

Trastuzumab is the only HER2/neu-directed therapy to have received Food and Drug Administration approval for the treatment of patients with metastatic breast cancer. The efficacy of trastuzumab...

Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens

Okada, N, Tsujino, M, Hagiwara, Y, Tada, A, Tamura, Y, Mori, K, ...

 Dendritic cells (DCs) loaded with tumour antigens have been successfully used to induce protective tumour immunity in murine models and human trials. However, it is still unclear which DC...

Down-regulation of Lsm1 is involved in human prostate cancer progression

Takahashi, S, Suzuki, S, Inaguma, S, Cho, Y-M, Ikeda, Y, Hayashi, N, ...

Elucidation of genetic alterations is an approach to understanding the underlying molecular mechanisms of progression of human prostate cancers. We have searched for genes differentially expressed in...