Tadashi Nishiya

Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation (2010)

Nishimoto, Arata, Lu, Lingyun, Hayashi, Misato, Nishiya, Tadashi, Horinouchi, Takahiro, Miwa, Soichi

Endothelin type A receptor (ETAR) plays an important role in some cardiovascular disorders where ETAR levels are increased. However, regulatory mechanisms for ETAR levels are unknown. Here, we...

Endothelin-1 decreases [Ca2+]i via Na+/Ca2+ exchanger in CHO cells stably expressing endothelin ETA receptor. (2007)

Horinouchi, Takahiro, Nishimoto, Arata, Nishiya, Tadashi, Lu, Lingyun, Kajita, Emi, Miwa, Soichi

Endothelin ETA receptor couples to Gq/11 protein that transduces a variety of receptor signals to modulate diverse cellular responses including Ca2+ mobilization. Stimulation of endothelin ETA...

Endothelin-1 decreases [Ca2+]i via Na+/Ca2+ exchanger in CHO cells stably expressing endothelin ETA receptor. (2007)

Horinouchi, Takahiro, Nishimoto, Arata, Nishiya, Tadashi, Lu, Lingyun, Kajita, Emi, Miwa, Soichi

Endothelin ETA receptor couples to Gq/11 protein that transduces a variety of receptor signals to modulate diverse cellular responses including Ca2+ mobilization. Stimulation of endothelin ETA...

OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN2 (2007)

Maekawa, Satoshi, Mori, Daisuke, Nishiya, Tadashi, Takikawa, Osamu, Horinouchi, Takahiro, Nishimoto, Arata, ...

A novel organic cation transporter OCTN2 is indispensable for carnitine transport across plasma membrane and subsequent fatty acid metabolism in the mitochondria. Here, we report a novel splice...

OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN2. (2007)

Maekawa, Satoshi, Mori, Daisuke, Nishiya, Tadashi, Takikawa, Osamu, Horinouchi, Takahiro, Nishimoto, Arata, ...

A novel organic cation transporter OCTN2 is indispensable for carnitine transport across plasma membrane and subsequent fatty acid metabolism in the mitochondria. Here, we report a novel splice...

Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2 (2006)

Nagai, Kazuhiko, Takikawa, Osamu, Kawakami, Naoko, Fukao, Mitsuhiro, Soma, Takamitsu, Oda, Atsushi, ...

Acetylcarnitine exerts therapeutic effects on some neurological disorders including Alzheimer’s disease. OCTN2 is known as a transporter for acetylcarnitine, but its expression in the brain is very...

Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2. (2006)

Nagai, Kazuhiko, Takikawa, Osamu, Kawakami, Naoko, Fukao, Mitsuhiro, Soma, Takamitsu, Oda, Atsushi, ...

Acetylcarnitine exerts therapeutic effects on some neurological disorders including Alzheimer's disease. OCTN2 is known as a transporter for acetylcarnitine, but its expression in the brain is very...

Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2. (2006)

Nagai, Kazuhiko, Takikawa, Osamu, Kawakami, Naoko, Fukao, Mitsuhiro, Soma, Takamitsu, Oda, Atsushi, ...

Acetylcarnitine exerts therapeutic effects on some neurological disorders including Alzheimer's disease. OCTN2 is known as a transporter for acetylcarnitine, but its expression in the brain is very...