Visualizing and clustering high throughput sub-cellular localization imaging (2008)
Hamilton Nicholas, Teasdale Rohan
Abstract Background The expansion of automatic imaging technologies has created a need to be able to efficiently compare and review large sets of image data. To enable comparisons of image data...
A role for SNX5 in the regulation of macropinocytosis (2008)
Lim Jet, Wang Jack, Kerr Markus, Teasdale Rohan, Gleeson Paul
Abstract Background The mechanisms and components that regulate macropinocytosis are poorly understood. Here we have investigated the role of sorting nexin 5 (SNX5) in the regulation of...
Fast automated cell phenotype image classification (2007)
Hamilton Nicholas, Pantelic Radosav, Hanson Kelly, Teasdale Rohan
Abstract Background The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respect,...
Forrest Alistair, Taylor Darrin, Fink J Lynn, Gongora M Milena, Flegg Cameron, Teasdale Rohan, ...
Abstract Background Protein kinases and protein phosphatases are the fundamental components of phosphorylation dependent protein regulatory systems. We have created a database for the protein...
Evaluation and comparison of mammalian subcellular localization prediction methods (2006)
Sprenger Josefine, Fink J Lynn, Teasdale Rohan
Abstract Background Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function of...