Mott Kevin, UnderHill David, Wechsler Steven, Town Terrence, Ghiasi Homayon
Abstract Background Macrophages and dendritic cells (DCs) play key roles in host defense against HSV-1 infection. Although macrophages and DCs can be infected by herpes simplex virus type 1 (HSV-1),...
Inflammaging as a prodrome to Alzheimer's disease (2008)
Giunta Brian, Fernandez Francisco, Nikolic William, Obregon Demian, Rrapo Elona, Town Terrence, ...
Abstract Recently, the term "inflammaging" was coined by Franceshci and colleagues to characterize a widely accepted paradigm that ageing is accompanied by a low-grade chronic up-regulation of...
The microglial "activation" continuum: from innate to adaptive responses (2005)
Town Terrence, Nikolic Veljko, Tan Jun
Abstract Microglia are innate immune cells of myeloid origin that take up residence in the central nervous system (CNS) during embryogenesis. While classically regarded as macrophage-like cells, it...