Synthesis of [7,7-H-2(2)]epibrassinolide (2007)
Khripach, V.A., Khripach, N.B., Zhabinskii, V.N., Zhiburtovich, Y.Y., Schneider, B.
Synthesis of labelled epibrassinolide containing two deuterium atoms in a position which is not subjected to isotopic exchange is reported. Key transformations include preparation of 6,7-seco...
A new type of steroids with a cyclobutane fragment in the AB-ring moiety (2006)
Khripach, V.A., Zhabinskii, V.N., Fando, G.P., Kuchto, A.I., Khripach, N.B., Groen, M.B., ...
The synthesis of a 5,10-seco steroid containing two double bonds in a AB-macrocycle as well as the preparation of a steroidal skeleton with a cyclobutane fragment is described. The structures of...
Khripach, V.A., Zhabinskii, V.N., Kuchto, A.I., Zhiburtovich, Y.Y., Gromak, V.V., Groen, M.B., ...
Treatment of 3 beta,17 beta-diacetoxy-5,10-secoandrost-1(10)-en-5-one with (BF3Et2O)-Et-. was shown to proceed with cleavage of the macrocycle and formation of a new compound containing a...
Isolation and structure elucidation of new radical oxidation products of 5-hydroxy steroids (2006)
Khripach, V.A., Zhabinskii, V.N., Kuchto, A.I., Zhiburtovich, Y.Y., Lyakhov, A.S., Govorova, A.A., ...
Three new products have been isolated from the lead-tetraacetate version of the hypoiodite oxidation of 3 beta,17 beta-diacetoxy-5-hydroxy-5 alpha-androstane. Along with the expected 1(10)unsaturated...
The synthesis of functionalized 13,14-seco-steroids via Grob fragmentation (2004)
Khripach, V.A., Zhabinskii, V.N., Fando, G.P., Kuchto, A.I., Lyakhov, A.S., Govorova, A.A., ...
A synthetic methodology for the synthesis of 13,14-seco-steroids with substituents at C-14 and C-17 is described. The approach involves Grob fragmentation of 14-hydroxy-17-tosylates,...
Synthesis of 13,14-secotestosterone derivatives (2004)
Khripach, V.A., Zhabinskii, V.N., Kuchto, A.I., Zhiburtovich, Y.Y., Fando, G.P., Lyakhov, A.S., ...
A number of testosterone analogs with a 13,14-secosteroidal fragment have been prepared from (13S)-13-iodo-6-methoxy-3, 5-cyclo-13,14-seco-5-androstan-14,17-dione. The key steps involved...
Khripach, V.A., Zhabinskii, V.N., Kuchto, A.I., Fando, G.P., Zhiburtovich, Y.Y., Lyakhov, A.S., ...
The synthesis of 13,14-seco steroids starting from easily available (13S)-13-iodo-6-methoxy-3,5-cyclo-13,14-seco-5-androsta-14,17-dione is described. The C-17 ketone was converted regioselectively...
Synthesis of [26,27-H-2H6] brassinosteroids from 23,24-bisnorcholenic acid methyl ester (2004)
Antonchick, Andrey P., Schneider, Bernd, Zhabinskii, V. N., Khripach, V. A.
Biosynthesis of 2,3-epoxybrassinosteroids in seedlings of Secale cereale (2003)
Antonchick, Andrey P., Schneider, Bernd, Zhabinskii, V. N., Konstantinova, Olga V., Khripach, V. A.
Synthesis of hexadeuterated 23-dehydroxybrassinosteroids (2002)
Khripach, V. A., Zhabinskii, V. N., Antonchick, Andrey P., Konstantinova, Olga V., Schneider, Bernd
Khripach, V. A., Zhabinskii, V. N., Konstantinova, Olga V., Khripach, N. B., Antonchick, Andrey P., Schneider, Bernd
Synthesis of [26-H-2(3)]brassinosteroids (2002)
Khripach, V. A., Zhabinskii, V. N., Konstantinova, Olga V., Antonchick, Andrey P., Schneider, Bernd
Synthesis of C-5'-alkyl substituted 17-spirofuran 19-norsteroids (2001)
Khripach, V.A., Zhabinskii, V.N., Tsavloskii, D.N., Drachenova, O.A., Ivanova, G.V., Konstantinova, O.V., ...
Studies on synthesis of 13,14-seco steroids (2001)
Khripach, V.A., Zhabinskii, V.N., Kotyatkina, A.I., Fando, G.P., Zhiburtovich, Y.Y., Lyakhov, A.S., ...
Radical oxidation of 17-functionalized 14alpha-hydroxy steroids (2001)
Khripach, V.A., Zhabinskii, V.N., Kotyatkina, A.I., Fando, G.P., Zhiburtovich, Y.Y., Lyakhov, A.S., ...
The radical oxidation of 14a-hydroxy steroids with various functional groups at C-17 was studied. Lead tetraacetate and ceric ammonium nitrate were used as oxidizing agents. It was shown that...