Colonic Adenoma Risk in Familial Colorectal Cancer—A Study of Six Extended Kindreds (2008)
Deborah W Neklason, Brett L Thorpe, Angel Ferrandez, Anil Tumbapura, Kenneth Boucher, Gilda Garibotti, ...
Curtin, Karen, Slattery, Martha L., Ulrich, Cornelia M., Bigler, Jeannette, Levin, Theodore R., Wolff, Roger K., ...
This study investigated associations between CpG island methylator phenotype (CIMP) colon cancer and genetic polymorphisms relevant to one-carbon metabolism and thus, potentially the provision of...
Samowitz, Wade S., Albertsen, Hans, Sweeney, Carol, Herrick, Jennifer, Caan, Bette J., Anderson, Kristin E., ...
Background: Cigarette smoking has been associated with microsatellite instability in sporadic colon cancer. Most microsatellite-unstable colon cancers have widespread methylation of CpG islands...
Linear IgA bullous dermatosis responsive to a gluten-free diet (2001)
Conleth A Egan, Eileen Pazderka Smith, Ted B Taylor, Laurence J Meyer, Wade S Samowitz, John J Zone
Slattery, Martha L., Curtin, Karen, Anderson, Kristin, Ma, Khe-Ni, Ballard, Linda, Edwards, Sandra, ...
Background: Microsatellite instability (MSI) has been reported to occur in approximately 10%–15% of colon tumors. MSI is characterized by the presence of mutations in tandemly repeated DNA...
BAT-26 and BAT-40 Instability in Colorectal Adenomas and Carcinomas and Germline Polymorphisms
Samowitz, Wade S., Slattery, Martha L., Potter, John D., Leppert, Mark F.
Analysis of the mononucleotide repeats BAT-26 and BAT-40 has reportedly revealed significant microsatellite instability in sporadic colorectal adenomas, whereas studies with dinucleotide and...
Samowitz, Wade S., Holden, Joseph A., Curtin, Karen, Edwards, Sandra L., Walker, Adrianne R., Lin, Heather A., ...
Some studies have shown an inverse relationship between microsatellite instability in colon cancer and mutations in p53 and K-ras, whereas others have not. We therefore evaluated these features in a...
Jones, Robert G., Li, Xiufen, Gray, Phillip D., Kuang, Jinqiu, Clayton, Frederic, Samowitz, Wade S., ...
Conditional deletion of β1 integrins in the intestinal epithelium, unlike in epidermal and mammary epithelia, of mice does not result in decreased cell adhesion and proliferation, but instead causes...
Confirmation of Single Exon Deletions in MLH1 and MSH2 Using Quantitative Polymerase Chain Reaction
Vaughn, Cecily P., Lyon, Elaine, Samowitz, Wade S.
Deletions of one or more exons in the mismatch repair genes MLH1 and MSH2 have been implicated in a significant fraction of hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome)....