Welch John

Inferring selection in the Anopheles gambiae species complex: an example from immune-related serine protease inhibitors (2009)

Obbard Darren, Welch John, Little Tom

Abstract Background Mosquitoes of the Anopheles gambiae species complex are the primary vectors of human malaria in sub-Saharan Africa. Many host genes have been shown to affect Plasmodium...

Correlates of substitution rate variation in mammalian protein-coding sequences (2008)

Welch John, Bininda-Emonds Olaf, Bromham Lindell

Abstract Background Rates of molecular evolution in different lineages can vary widely, and some of this variation might be predictable from aspects of species' biology. Investigating such...

The influence of body size and net diversification rate on molecular evolution during the radiation of animal phyla (2007)

Fontanillas Eric, Welch John, Thomas Jessica, Bromham Lindell

Abstract Background Molecular clock dates, which place the origin of animal phyla deep in the Precambrian, have been used to reject the hypothesis of a rapid evolutionary radiation of animal phyla...

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter (2006)

Liddiard Kate, Welch John, Lozach Jean, Heinz Sven, Glass Christopher, Greaves David

Abstract Background Macrophages (Mθ) play a central role in the innate immune response and in the pathology of chronic inflammatory diseases. Macrophages treated with Th2-type cytokines such as...