Y. Ogawa

Details der Publikationsliste

Zeitraum

1979 - 2009

Anzahl

154

Co-Autoren

Cardiovascular reflex responses to temporal reduction in arterial pressure during dexmedetomidine infusion: a double-blind, randomized, and placebo-controlled study (2009)

Kato, J., Ogawa, Y., Kojima, W., Aoki, K., Ogawa, S., Iwasaki, K.

BackgroundThe low and moderate doses of dexmedetomidine reduce arterial pressure and heart rate (HR), suggesting attenuation of sympathetic activity and dominance of cardiac-vagal activity. These...

Photon correlation in GaAs self-assembled quantum dots (2008)

Kuroda, T., Abbarchi, M., Mano, T., Watanabe, K., Yamagiwa, M., Kuroda, K., ...

We report on photon coincidence measurement in a single GaAs self-assembled quantum dot (QD) using a pulsed excitation light source. At low excitation, when a neutral exciton line was present in the...

Generation of the lower-thermospheric vertical wind estimated with the EISCAT KST radar at high latitudes during periods of moderate geomagnetic disturbance (2008)

Oyama, S., Watkins, B. J., Maeda, S., Shinagawa, H., Nozawa, S., Ogawa, Y., ...

Lower-thermospheric winds at high latitudes during moderately-disturbed geomagnetic conditions were studied using data obtained with the European Incoherent Scatter (EISCAT) Kiruna-Sodankylä-Tromsø...

Generation of the lower-thermospheric vertical wind estimated with the EISCAT KST radar at high latitudes during periods of moderate geomagnetic disturbance (2008)

Oyama, S., Watkins, B. J., Maeda, S., Shinagawa, H., Nozawa, S., Ogawa, Y., ...

Lower-thermospheric winds at high latitudes during moderately-disturbed geomagnetic conditions were studied using data obtained with the European Incoherent Scatter (EISCAT) Kiruna-Sodankylä-Tromsø...

Terahertz sensing method for protein detection using a thin metallic mesh (2007)

Yoshida, H., Ogawa, Y., Kawai, Y., Hayashi, S., Hayashi, A., Otani, C., ...

A label-free biological sensor, which is based on the resonant transmission phenomenon of a thin metallic mesh, is proposed in the terahertz wave region. By using this sensor, we demonstrate the...

For The Kekb Injector Linac (2007)

Flanagan Oide Akasaka, J. W. Flanagan, K. Oide, N. Akasaka, A. Enomoto, K. Furukawa, ...

A simple real-time beam tuning program has been developed for use at the KEK B-Factory injector linac. The program features the ability to adjust an arbitrary combination of parameters (e.g. magnet...

LATTICE DIAGNOSTICS USING SINGLE KICK CLOSED ORBIT AT KEKB (2007)

Y. Ohnishi, K. Akai, N. Akasaka, A. Enomoto, J. Flanagan, H. Fukuma, ...

We have measured beta functions using single kick closed orbit at KEKB. The measured beta functions were compared with the model lattice and gradient errors were extracted from the result in a beta...

Compensation of the Crossing Angle with Crab Cavities at KEKB (2007)

Abe, T., Akai, K., Akemoto, M., Akiyama, A., Arinaga, M., Ebihara, K., ...

Crab cavities have been installed in the KEKB B--Factory rings to compensate the crossing angle at the collision point and thus increase luminosity. The beam operation with crab crossing has been...

Particle precipitations during NEIAL events: simultaneous ground based observations at Svalbard (2007)

Lunde, J., Gustavsson, B., Løvhaug, U. P., Lorentzen, D. A., Ogawa, Y.

In this paper we present Naturally Enhanced Ion Acoustic Lines (NEIALs) observed with the EISCAT Svalbard Radar (ESR). For the first time, long sequences of NEIALs are recorded, with more than 50...

Particle precipitations during NEIAL events: simultaneous ground based observations at Svalbard (2007)

Lunde, J., Gustavsson, B., Løvhaug, U. P., Lorentzen, D. A., Ogawa, Y.

In this paper we present Naturally Enhanced Ion Acoustic Lines (NEIALs) observed with the EISCAT Svalbard Radar (ESR). For the first time, long sequences of NEIALs are recorded, with more than 50...

TRANS4: a new coupled electron/proton transport code – comparison to observations above Svalbard using ESR, DMSP and optical measurements (2007)

Simon, C., Lilensten, J., Moen, J., Holmes, J. M., Ogawa, Y., Oksavik, K., ...

We present for the first time a numerical kinetic/fluid code for the ionosphere coupling proton and electron effects. It solves the fluid transport equations up to the eighth moment, and the kinetic...

TRANS4: a new coupled electron/proton transport code – comparison to observations above Svalbard using ESR, DMSP and optical measurements (2007)

Simon, C., Lilensten, J., Moen, J., Holmes, J. M., Ogawa, Y., Oksavik, K., ...

We present for the first time a numerical kinetic/fluid code for the ionosphere coupling proton and electron effects. It solves the fluid transport equations up to the eighth moment, and the kinetic...

Growth suppression of antibiotic-resistant Salmonella typhimurium DT104 by a non-DT104 strain in vitro (2006)

Ngwai, Y.B., Adachi, Y., Ogawa, Y.

Growth suppression of antibiotic-resistant Salmonella typhimurium DT104 by a non-DT104 strain was investigated in vitro. Chromosomal mutants of eight antibiotic-resistant DT104 strains were generated...

Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries (2006)

Abbott, B., Abbott, R., Adhikari, R., Ageev, A., Agresti, J., Ajith, P., ...

We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an...

Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries (2006)

Abbott, B., Abbott, R., Adhikari, R., Ageev, A., Agresti, Juri, Ajith, P., ...

We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an...

Results of the search for inspiraling compact star binaries from TAMA300's observation in 2000-2004 (2006)

Akutsu, Tomomi, Akutsu, Tomotadu, Ando, Masaki, Arai, Koji, Araya, Akito, Asada, H., ...

We analyze the data of the TAMA300 detector to search for gravitational waves from inspiraling compact star binaries with masses of the component stars in the range 1M[sun]–3M[sun]. In this...

Volcanism in Response to Plate Flexure (2006)

Hirano, N., Takahashi, E., Yamamoto, J., Abe, N., Ingle, S.P., Kaneoka, I., ...

Volcanism on Earth is known to occur in three tectonic settings: divergent plate boundaries (such as mid-ocean ridges), convergent plate boundaries (such as island arcs), and hot spots. We report...

Naturally enhanced ion-acoustic lines at high altitudes (2006)

Ogawa, Y., Buchert, S. C., Fujii, R., Nozawa, S., Forme, F.

Naturally enhanced ion-acoustic lines (NEIALs) between 1200 and 1900 km altitude are investigated. The NEIALs were found in the background gates of data from the European Incoherent Scatter (EISCAT)...

Substorm topology in the ionosphere and magnetosphere during a flux rope event in the magnetotail (2006)

Amm, O., Nakamura, R., Frey, H. U., Ogawa, Y., Kubyshkina, M., Balogh, A., ...

On 13 August 2002, at ~23:00 UT, about 10 min after a substorm intensification, Cluster observes a flux rope in the central magnetotail, followed by a localised fast flow event about oneminute later....

Naturally enhanced ion-acoustic lines at high altitudes (2006)

Ogawa, Y., Buchert, S. C., Fujii, R., Nozawa, S., Forme, F.

Naturally enhanced ion-acoustic lines (NEIALs) between 1200 and 1900 km altitude are investigated. The NEIALs were found in the background gates of data from the European Incoherent Scatter (EISCAT)...

Substorm topology in the ionosphere and magnetosphere during a flux rope event in the magnetotail (2006)

Amm, O., Nakamura, R., Frey, H. U., Ogawa, Y., Kubyshkina, M., Balogh, A., ...

On 13 August 2002, at ~23:00 UT, about 10 min after a substorm intensification, Cluster observes a flux rope in the central magnetotail, followed by a localised fast flow event about oneminute later....

Phase I and pharmacokinetic study of oral fludarabine phosphate in relapsed indolent B-cell non-Hodgkin's lymphoma (2006)

Ogawa, Y., Hotta, T., Tobinai, K., Watanabe, T., Sasaki, Y., Minami, H., ...

Background: The primary objective of this study was to investigate the tolerability, efficacy and pharmacokinetic profile of oral fludarabine phosphate in relapsed patients with indolent B-cell...

Observations of diverging field-aligned ion flow with the ESR (2004)

Buchert, S. C., Ogawa, Y., Fujii, R., Van Eyken, A. P.

We report on observations of a diverging ion flow along the geomagnetic field that is often seen at the EISCAT Svalbard radar. The flow is upward above the peak of the electron density in the...

Observations of diverging field-aligned ion flow with the ESR (2004)

Buchert, S. C., Ogawa, Y., Fujii, R., Van Eyken, A. P.

We report on observations of a diverging ion flow along the geomagnetic field that is often seen at the EISCAT Svalbard radar. The flow is upward above the peak of the electron density in the...

Cluster observations of high-frequency waves in the exterior cusp (2004)

Khotyaintsev, Y., Vaivads, A., Ogawa, Y., Popielawska, B., André, M., Buchert, S., ...

We study wave emissions, in the frequency range from above the lower hybrid frequency up to the plasma frequency, observed during one of the Cluster crossings of a high-beta exterior cusp region on 4...

Cluster observations of high-frequency waves in the exterior cusp (2004)

Khotyaintsev, Y., Vaivads, A., Ogawa, Y., Popielawska, B., André, M., Buchert, S., ...

We study wave emissions, in the frequency range from above the lower hybrid frequency up to the plasma frequency, observed during one of the Cluster crossings of a high-beta exterior cusp region on 4...

Chiral Sigma Model with Pion Mean Field in Finite Nuclei (2003)

Ogawa, Y., Toki, H., Tamenaga, S., Shen, H., Hosaka, A., Sugimoto, S., ...

The properties of infinite matter and finite nuclei are studied by using the chiral sigma model in the framework of the relativistic mean field theory. We reconstruct an extended chiral sigma model...

Beam Switching and Beam Feedback Systems at KEKB Linac (2000)

Furukawa, K., Enomoto, A., Kamikubota, N., Kamitani, T., Matsumoto, T., Ogawa, Y., ...

The KEK 8-GeV electron / 3.5-GeV positron linac has been operated with very different beam specifications for downstream rings, KEKB, PF and PF-AR. For the reliable operation among these beam modes...

Ion upflow and downflow at the topside ionosphere observed by the EISCAT VHF radar (2000)

Endo, M., Fujii, R., Ogawa, Y., Buchert, S. C., Nozawa, S., Watanabe, S., ...

We have determined the MLT distribution and KP dependence of the ion upflow and downflow of the thermal bulk oxygen ion population based on a data analysis using the EISCAT VHF radar CP-7 data...

Ion upflow and downflow at the topside ionosphere observed by the EISCAT VHF radar (2000)

Endo, M., Fujii, R., Ogawa, Y., Buchert, S. C., Nozawa, S., Watanabe, S., ...

We have determined the MLT distribution and KP dependence of the ion upflow and downflow of the thermal bulk oxygen ion population based on a data analysis using the EISCAT VHF radar CP-7 data...

Frequency dependent power fluctuations: a feature of the ESR system or physical? (2000)

Ogawa, Y., Forme, F., Buchert, S. C.

The k-dependence of the received power in high signal-to-noise ratio (SNR) conditions, occurring for naturally enhanced ion-acoustic lines (NEIALs) and for real satellites, is investigated by using...

Frequency dependent power fluctuations: a feature of the ESR system or physical? (2000)

Ogawa, Y., Forme, F., Buchert, S. C.

The k-dependence of the received power in high signal-to-noise ratio (SNR) conditions, occurring for naturally enhanced ion-acoustic lines (NEIALs) and for real satellites, is investigated by using...

Compensation of Channel Information Error using First Order Extrapolation in Eigenbeam Space Division Multiplexing (E-SDM) (1998)

Nishimura, T., Tsutsumi, T., Ohgane, T., Ogawa, Y.

In multiple-input multiple-output (MIMO) systems, eigenbeam space division multiplexing (E-SDM) [1], [2] has higher performance compared to conventional SDM and an advantage that simple detection...

Novel Slip-Free Rapid Thermal Annealing of GaAs in Vacuum with Excellent Uniformity and Reproducibility. (1998)

Kohno, M., Hida, H., Ogawa, Y., Fujii, M., Maeda, T.

This paper describes novel rapid thermal annealing for GaAs wafers under vacuum conditions (VRTA) using a three-zone lamp power control method. The developed RTA technology eliminates generation of...

Microscopic description of light unstable nuclei with the stochastic variational method (1996)

Varga, K., Suzuki, Y., Arai, K., Ogawa, Y.

The structure of the light proton and neutron rich nuclei is studied in a microscopic multicluster model using the stochastic variational method. This approach enables us to describe the weakly bound...

Occupation probability of harmonic-oscillator quanta for microscopic cluster-model wave functions (1996)

Suzuki, Y., Arai, K., Ogawa, Y., Varga, K.

We present a new and simple method of calculating the occupation probability of the number of total harmonic-oscillator quanta for a microscopic cluster-model wave function. Examples of applications...

Structure of the mirror nuclei $^9$Be and $^9$B in a microscopic cluster model (1996)

Arai, K., Ogawa, Y., Suzuki, Y., Varga, K.

The structure of the mirror nuclei $^9$Be and $^9$B is studied in a microscopic $\alpha+ \alpha+ n$ and $\alpha+ \alpha+ p$ three-cluster model using a fully antisymmetrized 9-nucleon wave function....

Demonstration of the inner structure of a right atrial myxoma by transoesophageal echocardiography (1993)

OHSHIMA, H., KAWASHIMA, E., OGAWA, Y., TOBISE, K., ONODERA, S.

We report a case of a large right atrial myxoma. With the use of transoesophagal echocardiography, several cysts were idntifield within the tumour and necrotic tissue was differentiated from...

Calibration measurements for the efficiency and response function of the NE213 scintillator by a 252Cf spontaneous fission source-application of a two-dimensional pulse height analysis system (1991)

Akimoto, T., Suzuki, T., Murai, I., Narita, M., Ogawa, Y., 秋本, 正

The authors describe calibration measurements for the efficiency and response function of the NE213 scintillator as an application of a two-dimensional pulse height analysis system. In this method, a...

Calibration measurements for the efficiency and response function of the NE213 scintillator by a 252Cf spontaneous fission source-application of a two-dimensional pulse height analysis system (1991)

Akimoto, T., Suzuki, T., Murai, I., Narita, M., Ogawa, Y.

The authors describe calibration measurements for the efficiency and response function of the NE213 scintillator as an application of a two-dimensional pulse height analysis system. In this method, a...

Calibration measurements for the efficiency and response function of the NE213 scintillator by a 252Cf spontaneous fission source-application of a two-dimensional pulse height analysis system (1991)

Akimoto, T., Suzuki, T., Murai, I., Narita, M., Ogawa, Y.

The authors describe calibration measurements for the efficiency and response function of the NE213 scintillator as an application of a two-dimensional pulse height analysis system. In this method, a...

A dual-parameter multichannel analyzer by a dual-computer system (1990)

Akimoto, T., Murai, I., Kato, S., Chaki, S., Shoji, I., Ogawa, Y., ...

The design and feasibility of a simple and practical system for measuring two-parameter signals is reported. A dual-parameter multichannel pulse-height analyzer (MCA) which uses two central...

A dual-parameter multichannel analyzer by a dual-computer system (1990)

Akimoto, T., Murai, I., Kato, S., Chaki, S., Shoji, I., Ogawa, Y.

The design and feasibility of a simple and practical system for measuring two-parameter signals is reported. A dual-parameter multichannel pulse-height analyzer (MCA) which uses two central...

A dual-parameter multichannel analyzer by a dual-computer system (1990)

Akimoto, T., Murai, I., Kato, S., Chaki, S., Shoji, I., Ogawa, Y.

The design and feasibility of a simple and practical system for measuring two-parameter signals is reported. A dual-parameter multichannel pulse-height analyzer (MCA) which uses two central...

A dual-parameter multichannel analyzer using a personal computer (1989)

Akimoto, T., Murai, I., Chaki, S., Ogawa, Y., Shoji, I, 秋本, 正

The design of a practical system for measuring two-parameter signals is reported. To obtain constantly changing energy spectral of nuclear reactor assemblies due to repeated insertion of pulsed...

A dual-parameter multichannel analyzer using a personal computer (1989)

Akimoto, T., Murai, I., Chaki, S., Ogawa, Y., Shoji, I

The design of a practical system for measuring two-parameter signals is reported. To obtain constantly changing energy spectral of nuclear reactor assemblies due to repeated insertion of pulsed...

A dual-parameter multichannel analyzer using a personal computer (1989)

Akimoto, T., Murai, I., Chaki, S., Ogawa, Y., Shoji, I

The design of a practical system for measuring two-parameter signals is reported. To obtain constantly changing energy spectral of nuclear reactor assemblies due to repeated insertion of pulsed...

Inhibition and Promotion of Differentiated-Like Phenotype of a Human Lung Carcinoma in Athymic Mice by Natural and Recombinant Forms of Transforming Growth Factor- (1989)

Twardzik, D. R., Ranchalis, J. E., McPherson, J. M., Ogawa, Y., Gentry, L., Purchio, A., ...

Both structurally related forms of transforming growth factor-&bgr; (TGF-&bgr; types I and II) are potent inhibitors of tumor cell growth in vitro and can also modulate the differentiation of some...

Flowering in seedlings of Pharbitis nil induced by benzyladenine applied under a non-inductive daylength (1980)

Ogawa, Y., King, R. W.

Benzyladenine (BA) induced flowering when applied at a high concentration (10−3M) to the cotyledons of seedlings of Pharbitis nil held in a non-inductive photoperiod (continuous irradiation). The...

Establishment of photoperiodic sensitivity by benzyladenine and a brief red irradiation in dark grown seedlings of Pharbitis nil Chois. (1979)

Ogawa, Y., King, R. W.

Flowering of etiolated seedlings of Pharbitis nil resulted following a single, brief red irradiation prior to an inductive dark period. Following this irradiation benzyladenine sprayed on the...

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

Nakagawa, O, Ogawa, Y, Itoh, H, Suga, S, Komatsu, Y, Kishimoto, I, ...

We previously demonstrated that brain natriuretic peptide (BNP) is a cardiac hormone mainly produced in the ventricle, while the major production site of atrial natriuretic peptide (ANP) is the...

Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats.

Ogawa, Y, Masuzaki, H, Isse, N, Okazaki, T, Mori, K, Shigemoto, M, ...

The obese (ob) gene has recently been isolated through a positional cloning approach, the mutation of which causes a marked hereditary obesity and diabetes mellitus in mice. In the present study, we...

Isolation of Pseudomonas pickettii strains that degrade 2,4,6-trichlorophenol and their dechlorination of chlorophenols.

Kiyohara, H, Hatta, T, Ogawa, Y, Kakuda, T, Yokoyama, H, Takizawa, N

Three strains of Pseudomonas pickettii that can grow with 2,4,6-trichlorophenol (2,4,6-TCP) as the sole source of carbon and energy were isolated from different mixed cultures of soil bacterial...

Physiology of the potentiation of lethal endotoxin shock by streptococcal pyrogenic exotoxin in rabbits.

Murai, T, Ogawa, Y, Kawasaki, H, Kanoh, S

Streptococcal pyrogenic exotoxin (SPE) dramatically potentiates the lethal shock induced by gram-negative bacterial endotoxin. To provide further understanding of the mechanism underlying the...

Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene.

Ogawa, Y, Itoh, H, Tamura, N, Suga, S, Yoshimasa, T, Uehira, M, ...

Brain natriuretic peptide (BNP) is a cardiac hormone that occurs predominantly in the ventricle. To study the roles of BNP in chronic cardiovascular regulation, we isolated mouse BNP cDNA and genomic...

Molecular cloning of hamster brain and atrial natriuretic peptide cDNAs. Cardiomyopathic hamsters are useful models for brain and atrial natriuretic peptides.

Tamura, N, Ogawa, Y, Itoh, H, Arai, H, Suga, S, Nakagawa, O, ...

Brain and atrial natriuretic peptides (BNP and ANP) are cardiac hormones with diuretic, natriuretic, and vasodilatory activities. Cardiomyopathic hamsters are widely used animal models of heart...

Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.

Mukoyama, M, Nakao, K, Hosoda, K, Suga, S, Saito, Y, Ogawa, Y, ...

Using a specific radioimmunoassay for human brain natriuretic peptide (hBNP) with a monoclonal antibody, we have investigated its synthesis, secretion, and clearance in comparison with those of...

Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals.

Brandes, M E, Allen, J B, Ogawa, Y, Wahl, S M

Systemic administration of the cytokine, TGF beta 1, profoundly antagonized the development of polyarthritis in susceptible rats. TGF beta 1 administration (1 or 5 micrograms/animal), initiated one...

Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".

Suga, S, Nakao, K, Itoh, H, Komatsu, Y, Ogawa, Y, Hama, N, ...

C-type natriuretic peptide (CNP), the third member of the natriuretic peptide family, is thus far known to be distributed mainly in the central nervous system and is considered to act as a...

Serum leptin level is a regulator of bone mass

Elefteriou, F., Takeda, S., Ebihara, K., Magre, J., Patano, N., Ae Kim, C., ...

Leptin is a powerful inhibitor of bone formation in vivo. This antiosteogenic function involves leptin binding to its receptors on ventromedial hypothalamic neurons, the autonomous nervous system and...

Bovine leukemia virus: unique structural features of its long terminal repeats and its evolutionary relationship to human T-cell leukemia virus.

Sagata, N, Yasunaga, T, Ogawa, Y, Tsuzuku-Kawamura, J, Ikawa, Y

The nucleotide sequence of the long terminal repeat (LTR) of bovine leukemia virus, a unique oncogenic retrovirus of cattle, was determined. The LTR consisted of 530 base pairs (bp) with an inverted...

Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.

Furuno, N, Nishizawa, M, Okazaki, K, Tanaka, H, Iwashita, J, Nakajo, N, ...

Meiosis is characterized by the absence of DNA replication between the two successive divisions. In Xenopus eggs, the ability to replicate DNA develops during meiotic maturation, but is normally...

Complete nucleotide sequence of the genome of bovine leukemia virus: its evolutionary relationship to other retroviruses.

Sagata, N, Yasunaga, T, Tsuzuku-Kawamura, J, Ohishi, K, Ogawa, Y, Ikawa, Y

We report the complete 8714-nucleotide sequence of the integrated bovine leukemia virus genome and deduce the following genomic organization: 5' LTR-gag-pol-env-pXBL-3' LTR, where LTR represents a...

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

Nishizawa, M, Furuno, N, Okazaki, K, Tanaka, H, Ogawa, Y, Sagata, N

The c-mos proto-oncogene product (Mos), an essential component of the cytostatic factor responsible for meiotic arrest in vertebrate eggs, undergoes specific proteolysis soon after fertilization or...

Arylsulphatase and glycosulphatase of Charonia lampas. Substrate specificity towards sugar sulphate derivatives.

Hatanaka, H, Ogawa, Y, Egami, F

The specificity of the arylsulphatase and glycosulphatase enzymes of the marine mollusc Charonia lampas towards a number of carbohydrate sulphate esters was examined. The results confirm that the...

Meiotic cell cycle in Xenopus oocytes is independent of cdk2 kinase.

Furuno, N, Ogawa, Y, Iwashita, J, Nakajo, N, Sagata, N

In vertebrates, M phase-promoting factor (MPF), a universal G2/M regulator in eukaryotic cells, drives meiotic maturation of oocytes, while cytostatic factor (CSF) arrests mature oocytes at metaphase...

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

Shintani, T, Mizushima, N, Ogawa, Y, Matsuura, A, Noda, T, Ohsumi, Y

Autophagy is a cellular process for bulk degradation of cytoplasmic components. The attachment of Apg12p, a modifier with no significant similarity to ubiquitin, to Apg5p is crucial for autophagy in...

Alternative RNA splicing of the human endothelin-A receptor generates multiple transcripts.

Miyamoto, Y, Yoshimasa, T, Arai, H, Takaya, K, Ogawa, Y, Itoh, H, ...

In order to elucidate the regulatory mechanisms of expression of the human endothelin-A receptor (hET-AR) gene, we characterized hET-AR transcripts using reverse transcriptase (RT)-PCR analysis in a...

Inhibition of smooth-muscle myosin-light-chain phosphatase by Ruthenium Red.

Yamada, A, Sato, O, Watanabe, M, Walsh, M P, Ogawa, Y, Imaizumi, Y

Ruthenium Red (RuR) is widely used as an inhibitor of ryanodine receptor Ca(2+) release channels, but has additional effects such as the induction of Ca(2+) sensitization of contraction of...

Effects of sarin on the nervous system in rescue team staff members and police officers 3 years after the Tokyo subway sarin attack.

Nishiwaki, Y, Maekawa, K, Ogawa, Y, Asukai, N, Minami, M, Omae, K

Although the clinical manifestations of acute sarin poisoning have been reported in detail, no comprehensive study of the chronic physical and psychiatric effects of acute sarin poisoning has been...

Effect of luminal calcium on Ca2+ release channel activity of sarcoplasmic reticulum in situ.

Kurebayashi, N, Ogawa, Y

Ca2+ influx into empty SR in the absence of Ca2+ pump activity was determined in skinned frog skeletal muscle fibers and compared with Ca2+ efflux from loaded SR (i.e., Ca2+ release) to deepen our...

Role of Mg(2+) in Ca(2+)-induced Ca(2+) release through ryanodine receptors of frog skeletal muscle: modulations by adenine nucleotides and caffeine.

Murayama, T, Kurebayashi, N, Ogawa, Y

Mg(2+) serves as a competitive antagonist against Ca(2+) in the high-affinity Ca(2+) activation site (A-site) and as an agonist of Ca(2+) in the low-affinity Ca(2+) inactivation site (I-site) of the...

Results of omental flap transposition for deep sternal wound infection after cardiovascular surgery.

Yasuura, K, Okamoto, H, Morita, S, Ogawa, Y, Sawazaki, M, Seki, A, ...

OBJECTIVE: Our experience with omental flap transposition in the treatment of deep sternal wound infections is reviewed here with an emphasis on efficacy, risk factors for in-hospital mortality...

Exogenous transforming growth factor-beta 2 enhances connective tissue formation and wound strength in guinea pig dermal wounds healing by secondary intent.

Ksander, G A, Ogawa, Y, Chu, G H, McMullin, H, Rosenblatt, J S, McPherson, J M

The presence of transforming growth factor-beta (TGF-beta) at the site of acute injury, its ability to attract inflammatory and connective tissue cells, and its stimulatory effect on the deposition...

Increase by trifluoperazine in calcium sensitivity of myofibrils in a skinned fibre from frog skeletal muscle.

Kurebayashi, N, Ogawa, Y

1. Since it has been demonstrated that trifluoperazine (TFP) increases the affinity for Ca2+ of troponin C as well as calmodulin, the effect of TFP was examined on the Ca2+-induced tension in...

Human liver regeneration after major hepatic resection. A study of normal liver and livers with chronic hepatitis and cirrhosis.

Nagasue, N, Yukaya, H, Ogawa, Y, Kohno, H, Nakamura, T

The regenerative process was evaluated in terms of liver size, function, and histology in 28 adults who had major hepatic resection: hepatocellular carcinoma (HCC) in 21, secondary liver cancer from...

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

Nakagawa, O, Ogawa, Y, Itoh, H, Suga, S, Komatsu, Y, Kishimoto, I, ...

We previously demonstrated that brain natriuretic peptide (BNP) is a cardiac hormone mainly produced in the ventricle, while the major production site of atrial natriuretic peptide (ANP) is the...

Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats.

Ogawa, Y, Masuzaki, H, Isse, N, Okazaki, T, Mori, K, Shigemoto, M, ...

The obese (ob) gene has recently been isolated through a positional cloning approach, the mutation of which causes a marked hereditary obesity and diabetes mellitus in mice. In the present study, we...

Isolation of Pseudomonas pickettii strains that degrade 2,4,6-trichlorophenol and their dechlorination of chlorophenols.

Kiyohara, H, Hatta, T, Ogawa, Y, Kakuda, T, Yokoyama, H, Takizawa, N

Three strains of Pseudomonas pickettii that can grow with 2,4,6-trichlorophenol (2,4,6-TCP) as the sole source of carbon and energy were isolated from different mixed cultures of soil bacterial...

Physiology of the potentiation of lethal endotoxin shock by streptococcal pyrogenic exotoxin in rabbits.

Murai, T, Ogawa, Y, Kawasaki, H, Kanoh, S

Streptococcal pyrogenic exotoxin (SPE) dramatically potentiates the lethal shock induced by gram-negative bacterial endotoxin. To provide further understanding of the mechanism underlying the...

Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene.

Ogawa, Y, Itoh, H, Tamura, N, Suga, S, Yoshimasa, T, Uehira, M, ...

Brain natriuretic peptide (BNP) is a cardiac hormone that occurs predominantly in the ventricle. To study the roles of BNP in chronic cardiovascular regulation, we isolated mouse BNP cDNA and genomic...

Molecular cloning of hamster brain and atrial natriuretic peptide cDNAs. Cardiomyopathic hamsters are useful models for brain and atrial natriuretic peptides.

Tamura, N, Ogawa, Y, Itoh, H, Arai, H, Suga, S, Nakagawa, O, ...

Brain and atrial natriuretic peptides (BNP and ANP) are cardiac hormones with diuretic, natriuretic, and vasodilatory activities. Cardiomyopathic hamsters are widely used animal models of heart...

Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.

Mukoyama, M, Nakao, K, Hosoda, K, Suga, S, Saito, Y, Ogawa, Y, ...

Using a specific radioimmunoassay for human brain natriuretic peptide (hBNP) with a monoclonal antibody, we have investigated its synthesis, secretion, and clearance in comparison with those of...

Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals.

Brandes, M E, Allen, J B, Ogawa, Y, Wahl, S M

Systemic administration of the cytokine, TGF beta 1, profoundly antagonized the development of polyarthritis in susceptible rats. TGF beta 1 administration (1 or 5 micrograms/animal), initiated one...

Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".

Suga, S, Nakao, K, Itoh, H, Komatsu, Y, Ogawa, Y, Hama, N, ...

C-type natriuretic peptide (CNP), the third member of the natriuretic peptide family, is thus far known to be distributed mainly in the central nervous system and is considered to act as a...

Serum leptin level is a regulator of bone mass

Elefteriou, F., Takeda, S., Ebihara, K., Magre, J., Patano, N., Ae Kim, C., ...

Leptin is a powerful inhibitor of bone formation in vivo. This antiosteogenic function involves leptin binding to its receptors on ventromedial hypothalamic neurons, the autonomous nervous system and...

Bovine leukemia virus: unique structural features of its long terminal repeats and its evolutionary relationship to human T-cell leukemia virus.

Sagata, N, Yasunaga, T, Ogawa, Y, Tsuzuku-Kawamura, J, Ikawa, Y

The nucleotide sequence of the long terminal repeat (LTR) of bovine leukemia virus, a unique oncogenic retrovirus of cattle, was determined. The LTR consisted of 530 base pairs (bp) with an inverted...

Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.

Furuno, N, Nishizawa, M, Okazaki, K, Tanaka, H, Iwashita, J, Nakajo, N, ...

Meiosis is characterized by the absence of DNA replication between the two successive divisions. In Xenopus eggs, the ability to replicate DNA develops during meiotic maturation, but is normally...

Complete nucleotide sequence of the genome of bovine leukemia virus: its evolutionary relationship to other retroviruses.

Sagata, N, Yasunaga, T, Tsuzuku-Kawamura, J, Ohishi, K, Ogawa, Y, Ikawa, Y

We report the complete 8714-nucleotide sequence of the integrated bovine leukemia virus genome and deduce the following genomic organization: 5' LTR-gag-pol-env-pXBL-3' LTR, where LTR represents a...

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

Nishizawa, M, Furuno, N, Okazaki, K, Tanaka, H, Ogawa, Y, Sagata, N

The c-mos proto-oncogene product (Mos), an essential component of the cytostatic factor responsible for meiotic arrest in vertebrate eggs, undergoes specific proteolysis soon after fertilization or...

Arylsulphatase and glycosulphatase of Charonia lampas. Substrate specificity towards sugar sulphate derivatives.

Hatanaka, H, Ogawa, Y, Egami, F

The specificity of the arylsulphatase and glycosulphatase enzymes of the marine mollusc Charonia lampas towards a number of carbohydrate sulphate esters was examined. The results confirm that the...

Meiotic cell cycle in Xenopus oocytes is independent of cdk2 kinase.

Furuno, N, Ogawa, Y, Iwashita, J, Nakajo, N, Sagata, N

In vertebrates, M phase-promoting factor (MPF), a universal G2/M regulator in eukaryotic cells, drives meiotic maturation of oocytes, while cytostatic factor (CSF) arrests mature oocytes at metaphase...

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

Shintani, T, Mizushima, N, Ogawa, Y, Matsuura, A, Noda, T, Ohsumi, Y

Autophagy is a cellular process for bulk degradation of cytoplasmic components. The attachment of Apg12p, a modifier with no significant similarity to ubiquitin, to Apg5p is crucial for autophagy in...

Increase by trifluoperazine in calcium sensitivity of myofibrils in a skinned fibre from frog skeletal muscle.

Kurebayashi, N, Ogawa, Y

1. Since it has been demonstrated that trifluoperazine (TFP) increases the affinity for Ca2+ of troponin C as well as calmodulin, the effect of TFP was examined on the Ca2+-induced tension in...

Results of omental flap transposition for deep sternal wound infection after cardiovascular surgery.

Yasuura, K, Okamoto, H, Morita, S, Ogawa, Y, Sawazaki, M, Seki, A, ...

OBJECTIVE: Our experience with omental flap transposition in the treatment of deep sternal wound infections is reviewed here with an emphasis on efficacy, risk factors for in-hospital mortality...

Alternative RNA splicing of the human endothelin-A receptor generates multiple transcripts.

Miyamoto, Y, Yoshimasa, T, Arai, H, Takaya, K, Ogawa, Y, Itoh, H, ...

In order to elucidate the regulatory mechanisms of expression of the human endothelin-A receptor (hET-AR) gene, we characterized hET-AR transcripts using reverse transcriptase (RT)-PCR analysis in a...

Inhibition of smooth-muscle myosin-light-chain phosphatase by Ruthenium Red.

Yamada, A, Sato, O, Watanabe, M, Walsh, M P, Ogawa, Y, Imaizumi, Y

Ruthenium Red (RuR) is widely used as an inhibitor of ryanodine receptor Ca(2+) release channels, but has additional effects such as the induction of Ca(2+) sensitization of contraction of...

Effects of sarin on the nervous system in rescue team staff members and police officers 3 years after the Tokyo subway sarin attack.

Nishiwaki, Y, Maekawa, K, Ogawa, Y, Asukai, N, Minami, M, Omae, K

Although the clinical manifestations of acute sarin poisoning have been reported in detail, no comprehensive study of the chronic physical and psychiatric effects of acute sarin poisoning has been...

Effect of luminal calcium on Ca2+ release channel activity of sarcoplasmic reticulum in situ.

Kurebayashi, N, Ogawa, Y

Ca2+ influx into empty SR in the absence of Ca2+ pump activity was determined in skinned frog skeletal muscle fibers and compared with Ca2+ efflux from loaded SR (i.e., Ca2+ release) to deepen our...

Role of Mg(2+) in Ca(2+)-induced Ca(2+) release through ryanodine receptors of frog skeletal muscle: modulations by adenine nucleotides and caffeine.

Murayama, T, Kurebayashi, N, Ogawa, Y

Mg(2+) serves as a competitive antagonist against Ca(2+) in the high-affinity Ca(2+) activation site (A-site) and as an agonist of Ca(2+) in the low-affinity Ca(2+) inactivation site (I-site) of the...

Exogenous transforming growth factor-beta 2 enhances connective tissue formation and wound strength in guinea pig dermal wounds healing by secondary intent.

Ksander, G A, Ogawa, Y, Chu, G H, McMullin, H, Rosenblatt, J S, McPherson, J M

The presence of transforming growth factor-beta (TGF-beta) at the site of acute injury, its ability to attract inflammatory and connective tissue cells, and its stimulatory effect on the deposition...

Human liver regeneration after major hepatic resection. A study of normal liver and livers with chronic hepatitis and cirrhosis.

Nagasue, N, Yukaya, H, Ogawa, Y, Kohno, H, Nakamura, T

The regenerative process was evaluated in terms of liver size, function, and histology in 28 adults who had major hepatic resection: hepatocellular carcinoma (HCC) in 21, secondary liver cancer from...

The adjuvant activity of a non-toxic, water-soluble glycopeptide present in large quantities in the culture filtrate of Mycobacterium tuberculosis strain DT.

Stewart-Tull, D E, Shimono, T, Kotani, S, Kato, M, Ogawa, Y, Yamamura, Y, ...

A water-soluble mycobacterial glycopeptide was obtained in large quantities from the culture supernatant fluid of M. tuberculosis strain DT. This glycopeptide was strongly adjuvant-active when...

Effect of recombinant interleukin 2 on hepatitis B e antigen positive chronic hepatitis.

Onji, M, Kondoh, H, Horiike, N, Yamaguchi, S, Ogawa, Y, Kumon, I, ...

Eleven patients with hepatitis B (HB) virus related chronic hepatitis were treated with recombinant interleukin 2 (rIL 2). Two hundred and fifty to 1000 units were given intravenously once daily for...

Dry eye after haematopoietic stem cell transplantation

Ogawa, Y., Okamoto, S., Wakui, M., Watanabe, R., Yamada, M., Yoshino, M., ...

AIMS—To determine the incidence, natural course, and severity of dry eye occurring or worsening after haematopoietic stem cell transplantation (SCT).
METHODS—At a tertiary care hospital,...

Leptin inhibits stress-induced apoptosis of T lymphocytes

FUJITA, Y, MURAKAMI, M, OGAWA, Y, MASUZAKI, H, TANAKA, M, OZAKI, S, ...

Leptin, which is secreted by adipocytes, the placenta and the stomach, not only controls appetite through leptin receptors in the hypothalamus but also regulates cell-mediated immunity. In this study...

Latency of the Achilles tendon reflex for detection of reduced functions of the peripheral nervous system in workers exposed to lead.

Ogawa, Y, Hirata, M, Okayama, A, Ichikawa, Y E, Goto, S

The latency of the soleus muscle potential, evoked by a tap of the Achilles tendon, was used in the mass assessment of healthy male workers exposed to lead. Three groups were studied: a control, a...

Plasma leptin levels and cardiac sympathetic function in patients with obstructive sleep apnoea-hypopnoea syndrome

Shimizu, K, Chin, K, Nakamura, T, Masuzaki, H, Ogawa, Y, Hosokawa, R, ...

Background: The control of body weight and cardiac sympathetic function in patients with obstructive sleep apnoea-hypopnoea syndrome (OSAHS) are important because both factors have significant...

A Theory of Optimum Tariff Under Revenue Constraint.

Hatta, T., Ogawa, Y.

This paper analyzes the revenue-constrained optimum tariff problem. When a fixed level of tax revenue has to be collected only from tariffs, an efficient resource allocation can not be achieved by...

Microvessel quantitation in invasive breast cancer by staining for factor VIII-related antigen.

Ogawa, Y., Chung, Y. S., Nakata, B., Takatsuka, S., Maeda, K., Sawada, T., ...

The clinical importance of microvessel quantitation as a prognostic indicator in invasive breast cancer was examined. This study included 155 patients with invasive breast cancer, with a median...

Tumour angiogenesis and tumour cell proliferation as prognostic indicators in gastric carcinoma.

Maeda, K., Chung, Y. S., Takatsuka, S., Ogawa, Y., Onoda, N., Sawada, T., ...

Tumour growth depends on neovascularisation and tumour cell proliferation. Factor VIII-related antigen (F-VIII RA) localises to vascular endothelium. Expression of proliferating cell nuclear antigen...

Clinical significance of serum CYFRA 21-1 in gastric cancer.

Nakata, B., Chung, Y. S., Kato, Y., Ogawa, M., Ogawa, Y., Inui, A., ...

We studied the clinical significance of the soluble cytokeratin 19 fragment detected with monoclonal antibody CYFRA 21-1 in the sera of patients with histologically proven gastric cancer. Sera of 110...

Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma.

Maeda, K., Chung, Y. S., Ogawa, Y., Takatsuka, S., Kang, S. M., Ogawa, M., ...

It is known that angiogenesis plays an important role in the growth and metastasis of solid tumours. Several angiogenic factors have been identified and platelet-derived endothelial cell growth...

Immune reaction induced by X-rays and pions and its stimulation by schizophyllan (SPG).

Inomata, T., Goodman, G. B., Fryer, C. J., Chaplin, D. J., Palcic, B., Lam, G. K., ...

Female C57BL/6 mice aged 6-8 weeks with transplanted Lewis lung cancer cells were used to investigate the anti-tumour effects and immune reactions in tumour tissue induced by X-ray and pion...