Sequence features associated with microRNA strand selection in humans and flies (2009)
Hu, Hai, Yan, Zheng, Xu, Ying, Hu, Hao, Menzel, Corinna, Zhou, Yan, ...
Abstract Background During microRNA (miRNA) maturation in humans and flies, Drosha and Dicer cut the precursor transcript, thereby producing a short RNA duplex. One strand of this duplex becomes a...
Plant Modeling Based on 3D Reconstruction (2009)
Tonglin Zhu, Feng Tian, Yan Zhou, Hock Soon Seah, Xiaolong Yan
Abstract—In this paper a 3D plant modeling method based on projection image is presented. A novel simple 3D reconstruction algorithm is proposed and its calibration speed and precision are...
Xu, Tao, Gu, JianLei, Zhou, Yan, Du, LinFang
Abstract Background Gene set analysis based on Gene Ontology (GO) can be a promising method for the analysis of differential expression patterns. However, current studies that focus on individual GO...
Lei Wang, Yan Zhou, Ya-Xi Huang, Jin-Xiao Mi
The title compound, ammonium potassium iron(III) phosphate fluoride, (NH4)0.875K0.125FePO4F, is built from zigzag chains ∞1{[FeO4F2]7−}, with Fe3+ in a distorted octahedral coordination,...
Bis(benzoylacetonato)bis(1,3-di-4-pyridylpropane)manganese(II) (2009)
Yan Zhou, Wen-Na Zhao, Lei Han
In the title compound, [Mn(C10H9O2)2(C13H14N2)2], the MnII ion lies on a crystallographic inversion center and has a slightly distorted octahedral coordination environment. Weak π–π...
catena-Poly[[bis(4-methylbenzenethiolato)cadium(II)]-μ-1,3-di-4-pyridylpropane] (2009)
In the title compound, [Cd(C7H7S)2(C13H14N2)]n, the unique CdII ion, located on a twofold rotation axis, is coordinated by two S atoms and two N atoms in a slightly distorted tetrahedral environment....
Zhou, Yan, Pijuan, Maite, Zeng, Raymond J., Yuan, Zhiguo
For decades, glycolysis has been generally accepted to supply the reducing power for the anaerobic conversion of volatile fatty acids (VFAs) to polyhydroxyalkanoates (PHAs) by polyphosphate...
Spin momentum transfer effects for spintronic device applications (2009)
The recent discovery that a spin-polarized current can exert a large torque on a ferromagnet, through direct transfer of spin angular momentum, offers the possibility of electrical current controlled...
Brejová, Brona, Vinar, Tomás, Chen, Yangyi, Wang, Shengyue, Zhao, Guoping, Brown, Daniel G., ...
We have developed a novel method for estimating the parameters of hidden Markov models for gene finding in newly sequenced species. Our approach does not rely on curated training data sets, but...
Spin momentum transfer effects for spintronic device applications (2009)
The recent discovery that a spin-polarized current can exert a large torque on a ferromagnet, through direct transfer of spin angular momentum, offers the possibility of electrical current controlled...
Visible-light photoresponsive heterojunctions of (Nb-Ti-Si) and (Bi/Bi-o) nanoparticles (2009)
Lim, Melvin, Zhou, Yan, Guo, Yanan, Sun, Chenghua, Wood, Barry, Wang, Lianzhou, ...
The increasing motivation to seek alternative sources of clean and sustainable energy has intensified, due to a growing awareness that fossil fuels are finite in quantity, and that the combustion...
Xu, Tao, Du, LinFang, Zhou, Yan
Abstract Background Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries of currently...
Zhou, Yan, Bonetti, S., Zha, C. L., Akerman, Johan
Using non-linear system theory and numerical simulations we map out the static and dynamic phase diagram in zero applied field of a spin torque oscillator with a tilted polarizer (TP-STO).We find...
Minimum Spanning Tree Based Clustering Algorithms (2008)
R Grygorash, Yan Zhou, Zach Jorgensen
The minimum spanning tree clustering algorithm is known to be capable of detecting clusters with irregular boundaries. In this paper, we propose two minimum spanning tree based clustering algorithms....
Spin-torque oscillator based on tilted magnetization of the fixed layer (2008)
Zhou, Yan, Zha, C. L., Bonetti, S., Persson, J., Akerman, Johan
The spin torque oscillator (STO), where the magnetization of the fixed layer is tilted out of the film plane, is capable of strong microwave signal generation in zero magnetic field. Through...
Combating Good Word Attacks on Statistical Spam Filters with Multiple Instance Learning (2008)
Yan Zhou, Zach Jorgensen, Meador Inge
Statistical spam filters are known to be vulnerable to adversarial attacks. One such adversarial attack, known as the Good Word Attack, thwarts spam filters by appending to spam messages sets of...
Smartacking: Improving TCP Performance from the Receiving End (2008)
Daniel K. Bl, Sally A. Goldman, Sergey Gorinsky, Yan Zhou, Daniel R. Dooly
Abstract — We present smartacking, a technique that improves performance of Transmission Control Protocol (TCP) via adaptive generation of acknowledgments (ACKs) at the receiver. When the...
1 Introduction Teaching Surface Design Made Easy ∗ (2008)
Yan Zhou, Yuan Zhao, John L. Lowther, Ching-kuang Shene
All popular computer graphics textbooks have chapters on curves and surfaces [1, 5, 6, 7]. Teaching these chapters
Villarruel, Antonia M., Loveland-Cherry, Carol, Ronis, David L., Zhou, Yan, Gallegos, Esther C.
Objetivo. Determinar la eficacia de una intervención conductual-educativa diseñada para disminuir las conductas sexuales de riesgo de VIH/SIDA y embarazos no planeados de adolescentes mexicanos....
1 Cross-Sectional Design: A Tool for Computer Graphics and Computer-Aided Design Courses (2007)
Yuan Zhao, Yan Zhou, John L. Lowther, Ching-kuang Shene
Abstract--- Teaching curve and surface design in a computer graphics or a computer-aided design course is a challenge because of the very involved mathematics, the lack of easy-to-use tools, and the...
An Interactive Surface Design Tool (2007)
Yan Zhou, Yuan Zhao, Houghton Mi
Teaching surface design in computer graphics, visualization and computer-aided design courses usually requires involved mathematics that students feel very difficult to grasp. This poster discusses a...
In ICML 2000 Enhancing Supervised Learning with Unlabeled Data (2007)
In many practical learning scenarios, there is a small amount of labeled data along with a large pool of unlabeled data. Many supervised learning algorithms have been developed and extensively...
Curve and surface construction is an important topic in computer graphics, computer-aided design, geometric modeling and visualization courses. In addition to Bezier, B-spline and NURBS,...
Cross-Sectional Design: ATool for Computer Graphics and Computer-Aided Design Courses (2007)
Yuan Zhao, Yan Zhou, John L. Lowther, Ching-kuang Shene
Abstract | Teaching curve and surface design in a computer graphics or a computer-aided design course is a challenge because of the very involved mathematics, the lack of easy-to-use tools, and the...
Evaluation of the models handling heterotachy in phylogenetic inference (2007)
Zhou, Yan, Rodrigue, Nicolas, Lartillot, Nicolas, Philippe, Hervé
Abstract Background The evolutionary rate at a given homologous position varies across time. When sufficiently pronounced, this phenomenon – called heterotachy – may produce artefactual...
Porcine adenovirus type 3 E1Blargeprotein downregulates the induction of IL-8 (2007)
Zhou, Yan, Ficzycz, Andrew, Tikoo, Suresh
Abstract Replication-defective (E1-E3 deleted) adenovirus vector based gene delivery results in the induction of cytokines including IL-8, which may contribute to the development of inflammatory...
Wang, Wei, Zhong, Jing, Su, Bing, Zhou, Yan, Wang, Yi-Quan
Identification of conserved genomic regions within and between different genomes is crucial when studying genome evolution. Here, we described regions of strong synteny conservation between...
Tikoo, Suresh K, Babiuk, Lorne A, Zhou, Yan
Influenza A virus infection activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, but the mechanism is not clear. Here, it is reported that influenza A virus NS1 protein is responsible for...
Nuclear Retention of Multiply Spliced HIV-1 RNA in Resting CD4+ T Cells (2006)
Kara G. Lassen, Kasra X. Ramyar, Justin R. Bailey, Yan Zhou, Robert F. Siliciano
HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). We describe here a novel post-transcriptional block...
English Language-culture and the Lifestyle of Urban Women in Contemporary China (2006)
The purpose of this research paper was study to what extent English language-culture has impacted the lifestyle of contemporary Chinese women in urban area. To be more elaborate, this research aimed...
Essays on international reserves in developing countries / (2006)
Thesis (Ph.D.)-University of California, Santa Cruz, 2006.
Wang, Wei, Zhong, Jing, Su, Bing, Zhou, Yan, Wang, Yi-Quan
Identification of conserved genomic regions within and between different genomes is crucial when studying genome evolution. Here, we described regions of strong synteny conservation between...
A Novel Post-transcriptional Block in Gene Expression Contributes to HIV-1 Latency In Vivo (2005)
Lassen, Kara G, Ramyar, Kasra X, Bailey, Justin R, Zhou, Yan, Siliciano, Robert F
No abstract available.
Heterotachy and long-branch attraction in phylogenetics (2005)
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
Abstract Background Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much...
The Genomes of Oryza sativa: A History of Duplications (2005)
Jun Yu, Jun Wang, Wei Lin, Songgang Li, Heng Li, Jun Zhou, ...
Comparative genome sequencing of indica and japonica rice reveals that duplication of genes and genomic regions has played a major part in the evolution of grass genomes.
The Genomes of Oryza sativa: A History of Duplications (2005)
Jun Yu, Jun Wang, Wei Lin, Songgang Li, Heng Li, Jun Zhou, ...
We report improved whole-genome shotgun sequences for the genomes of indica and japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the drafts of 2002. Tested...
The Chinese intellectuals of modern times attempted to rescue Chinese culture at three levels, namely, technology, system and discourse. This rescue campaign started from the Opium War of the 1840s...
Heterotachy and long-branch attraction in phylogenetics (2005)
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
Affiliation: Département de Biochimie, Faculté de médecine, Université de Montréal
Heterotachy and long-branch attraction in phylogenetics. (2005)
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
BACKGROUND: Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much more...
Heterotachy and long-branch attraction in phylogenetics. (2005)
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
BACKGROUND: Probabilistic methods have progressively supplanted the Maximum Parsimony (MP) method for inferring phylogenetic trees. One of the major reasons for this shift was that MP is much more...
Optimization of fiber shapes in biocomposites (2005)
Thesis (Ph. D.)--University of Notre Dame, 2005.
Abstract.
Optimization of fiber shapes in biocomposites [electronic resource] / (2005)
Thesis (Ph. D.)--University of Notre Dame, 2005.
OSW-1: a Natural Compound With Potent Anticancer Activity and a Novel Mechanism of Action (2005)
Zhou, Yan, Garcia-Prieto, Celia, Carney, Dennis A., Xu, Rui-hua, Pelicano, Helene, Kang, Ying, ...
The naturally occurring compound 3β,16β,17α-trihydroxycholest-5-en-22-one 16-O-(2-O-4-methoxybenzoyl-β-D-xylopyranosyl)-(1→3)-(2-O-acetyl-α-L-arabinopyranoside) (OSW-1) is found in the bulbs...
The chemokine GRO-{alpha} (CXCL1) confers increased tumorigenicity to glioma cells (2005)
Zhou, Yan, Zhang, Jing, Liu, Qiang, Bell, Robert, Muruve, Daniel A., Forsyth, Peter, ...
The chemokine GRO-α (CXCL1) has been found to mediate the proliferation of glia progenitor cells during neural development. As malignant gliomas are thought to arise from glia progenitors or their...
The chemokine GRO-{alpha} (CXCL1) confers increased tumorigenicity to glioma cells (2005)
Zhou, Yan, Zhang, Jing, Liu, Qiang, Bell, Robert, Muruve, Daniel A., Forsyth, Peter, ...
The chemokine GRO-α (CXCL1) has been found to mediate the proliferation of glia progenitor cells during neural development. As malignant gliomas are thought to arise from glia progenitors or their...
An Empirical Assessment of Long-Branch Attraction Artefacts in Deep Eukaryotic Phylogenomics (2005)
Brinkmann, Henner, Van Der Giezen, Mark, Zhou, Yan, De Raucourt, Gaëtan Poncelin, Philippe, Hervé
In the context of exponential growing molecular databases, it becomes increasingly easy to assemble large multigene data sets for phylogenomic studies. The expected increase of resolution due to the...
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms (2004)
Liu, Bin, Wang, Jun, Zhang, Yong, Yang, Xu, Zhang, Zengjin, ...
We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms (SNPs). This map is based on a comparison of the sequences of three domestic chicken...
Diversification Limited by Absence of Short Sales: the Chinese Case. (2004)
Rapport de recherche
The control of embryogenic competence in Alfalfa (Medicago falcata L.) / (2004)
Thesis (Ph.D.)--De Montfort University, 2004.
GEPIS--quantitative gene expression profiling in normal and cancer tissues (2004)
Zhang, Yan, Eberhard, David A., Frantz, Gretchen D., Dowd, Patrick, Wu, Thomas D., Zhou, Yan, ...
Motivation: Expression profiling in diverse tissues is fundamental to understanding gene function as well as therapeutic target identification. The vast collection of expressed sequence tags (EST)...
GEPIS--quantitative gene expression profiling in normal and cancer tissues (2004)
Zhang, Yan, Eberhard, David A., Frantz, Gretchen D., Dowd, Patrick, Wu, Thomas D., Zhou, Yan, ...
Motivation: Expression profiling in diverse tissues is fundamental to understanding gene function as well as therapeutic target identification. The vast collection of expressed sequence tags (ESTs)...
GEPIS--quantitative gene expression profiling in normal and cancer tissues (2004)
Zhang, Yan, Eberhard, David A., Frantz, Gretchen D., Dowd, Patrick, Wu, Thomas D., Zhou, Yan, ...
Motivation: Expression profiling in diverse tissues is fundamental to understanding gene function as well as therapeutic target identification. The vast collection of expressed sequence tags (EST)...
Zhou, Yan, Stassen, Jean-Marie
The serpin plasminogen activator inhibitor-1 (PAI-1) is a well-known risk factor for thromboembolic and cardiovascular diseases. Many efforts have been made to reveal structure-function relationship...
Zhou, Yan, Huang, Guyang Matthew, Wei, Liping
Motivation: More and more often, a gene is epitomized by a large number of sequences in GenBank. This high redundancy makes it very difficult to identify a unique best match for a query sequence from...
Enhancing supervised learning with unlabeled data / (2001)
Thesis (D. Sc.)--Washington University, 2001. Dept. of Computer Science.
Enhancing supervised learning with unlabeled data (2000)
In many practical learning scenarios, there is a small amount of labeled data along with a large pool of unlabeled data. Many supervised learning algorithms have been developed and extensively...
Surface interpolation and approximation /--by Yan Zhou. (1999)
Thesis (M.S.)--Michigan Technological University, 1999.
Substitution reactions using trichloroisocyanuric acid with triphenylphosphine / (1999)
Thesis (M.S.)--California State University, Fullerton, 1999.
Cross-Sectional Design: A Tool for Computer Graphics and Computer-Aided Design Courses (1999)
Yan Zhou, Yan Zhou, John L. Lowther, Ching-kuang Shene
Teaching curve and surface design in a computer graphics or a computer-aided design course is a challenge because of the very involved mathematics, the lack of easy-to-use tools, and the differing...
Ho, Seng T., Zhou, Yan, Chow, Weng W., Arakawa, Yasuhiko
The proceedings from the Photonics Technology into the 21st Century: Semiconductors, Microstructures, and Nanostructures is presented.
Giessen, Univ., Diss., 1998.
β-amyloid Neurotoxicity (1997)
Increasing evidence suggests that free radical-mediated oxidative damage to various biologically important macromolecules correlates with the normal aging process. Alzheimer's disease is a...
Adaptive resonance neural networks and their applications in cell formation problem / (1997)
Typescript (photocopy).
A self-stabilizing distributed maximum flow algorithm /--by Yan Zhou. (1996)
Typescript (photocopy)
Hyperspherical close-coupling calculations of positron on hydrogen-like atom collisions / (1996)
Thesis (Ph. D.)--Kansas State University, 1996.
Hyperspherical close-coupling method is used to calculate the elastic, positronium formation and excitation cross sections for positron collisions with atomic hydrogen at energies below the H(n=4)...
Typescript.
Typescript.
Ra G. Dykes, Xiaodong Zhang, Yan Zhou, Haixu Yang
Segmentation and other image processing operations rely on convolution calculations with heavy computational and memory access demands. This paper presents an analysis of a texture segmentation...
Cook Neural Network Control for A Fire-Fighting Robot (1994)
Yan Zhou, Dawn Wilkins, Robert P. Cook
Abstract. The paper dis cusses the development of an associative, neural network as an on-line algorithm to train and control a fire-fighting robot. Learning is externally supervised with encoded...
Sandra Dykes, Ra G. Dykes, Xiaodong Zhang, Yan Zhou, Haixu Yang
Segmentation and other image processing operations rely on convolution calculations with heavy computational and memory access demands. This paper presents an analysis of a texture segmentation...
The Chinese intellectuals of modern times attempted to rescue Chinese culture at three levels, namely, technology, system and discourse. This rescue campaign started from the Opium War of the 1840s...
Cha, Jennifer N., Shimizu, Katsuhiko, Zhou, Yan, Christiansen, Sean C., Chmelka, Bradley F., Stucky, Galen D., ...
Nanoscale control of the polymerization of silicon and oxygen determines the structures and properties of a wide range of siloxane-based materials, including glasses, ceramics, mesoporous molecular...
Poly(ADP-ribose) polymerase-1 is required for efficient HIV-1 integration
Ha, Hyo Chol, Juluri, Krishna, Zhou, Yan, Leung, Steve, Hermankova, Monika, Snyder, Solomon H.
Poly(ADP-ribose) polymerase-1 (PARP-1; EC 2.4.2.30) is an abundant nuclear enzyme, activated by DNA strand breaks to attach up to 200 ADP-ribose groups to nuclear proteins. As retroviral infection...
Gu, Bai-Wei, Xiong, Hui, Zhou, Yan, Chen, Bing, Wang, Li, Dong, Shuo, ...
The physiologic actions of retinoic acids (RAs) are mediated through RA receptors (RARs) and retinoid X receptors (RXRs). The RARα gene has drawn particular attention because it is the common target...
Pierson, Theodore C., Zhou, Yan, Kieffer, Tara L., Ruff, Christian T., Buck, Christopher, Siliciano, Robert F.
Most current evidence suggests that the infection of resting CD4+ T cells by human immunodeficiency virus type 1 (HIV-1) is not productive due to partial or complete blocks in the viral life cycle at...
Latency in Human Immunodeficiency Virus Type 1 Infection: No Easy Answers
Persaud, Deborah, Zhou, Yan, Siliciano, Janet M., Siliciano, Robert F.
Hermankova, Monika, Siliciano, Janet D., Zhou, Yan, Monie, Daphne, Chadwick, Karen, Margolick, Joseph B., ...
In individuals with human immunodeficiency virus type 1 (HIV-1) infection, a small reservoir of resting memory CD4+ T lymphocytes carrying latent, integrated provirus persists even in patients...
Zhang, Haili, Zhou, Yan, Alcock, Cecily, Kiefer, Tara, Monie, Daphne, Siliciano, Janet, ...
Human immunodeficiency virus type 1 (HIV-1)-infected individuals who develop drug-resistant virus during antiretroviral therapy may derive benefit from continued treatment for two reasons. First,...
Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface
Red-Horse, Kristy, Zhou, Yan, Genbacev, Olga, Prakobphol, Akraporn, Foulk, Russell, McMaster, Michael, ...
Trophoblasts, the specialized cells of the placenta, play a major role in implantation and formation of the maternal-fetal interface. Through an unusual differentiation process examined in this...
The analysis of large-scale gene expression correlated to the phase changes of the migratory locust
Kang, Le, Chen, XiangYong, Zhou, Yan, Liu, BoWan, Zheng, Wei, Li, RuiQiang, ...
The migratory locust is one of the most notorious agricultural pests that undergo a well known reversible, density-dependent phase transition from the solitary to the gregarious. To demonstrate the...
The Genomes of Oryza sativa: A History of Duplications
Yu, Jun, Wang, Jun, Lin, Wei, Li, Songgang, Li, Heng, Zhou, Jun, ...
We report improved whole-genome shotgun sequences for the genomes of indica and japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the drafts of 2002. Tested...
Kinetics of Human Immunodeficiency Virus Type 1 Decay following Entry into Resting CD4+ T Cells
Zhou, Yan, Zhang, Haili, Siliciano, Janet D., Siliciano, Robert F.
In untreated human immunodeficiency virus type 1 (HIV-1) infection, most viral genomes in resting CD4+ T cells are not integrated into host chromosomes. This unintegrated virus provides an inducible...
Monie, Daphne, Simmons, Rachel P., Nettles, Richard E., Kieffer, Tara L., Zhou, Yan, Zhang, Haili, ...
A latent reservoir for human immunodeficiency virus type 1 (HIV-1) consisting of integrated provirus in resting memory CD4+ T cells prevents viral eradication in patients on highly active...
Numb Proteins Specify Asymmetric Cell Fates via an Endocytosis- and Proteasome-Independent Pathway†
Tang, Haiyan, Rompani, Santiago B., Atkins, Joshua B., Zhou, Yan, Osterwalder, Thomas, Zhong, Weimin
Numb proteins are evolutionarily conserved signaling molecules that make the daughter cells different after asymmetric divisions by segregating to only one daughter. They contain distinct binding...
Wu, Terry H., Hutt, Julie A., Garrison, Kristin A., Berliba, Lyudmila S., Zhou, Yan, Lyons, C. Rick
The inhalation of Francisella tularensis biovar A causes pneumonic tularemia associated with high morbidity and mortality rates in humans. Exposure to F. tularensis usually occurs by accident, but...
Heterotachy and long-branch attraction in phylogenetics
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
Nuclear Retention of Multiply Spliced HIV-1 RNA in Resting CD4+ T Cells
Lassen, Kara G, Ramyar, Kasra X, Bailey, Justin R, Zhou, Yan, Siliciano, Robert F
HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). We describe here a novel post-transcriptional block...
Red-Horse, Kristy, Rivera, Jose, Schanz, Andrea, Zhou, Yan, Winn, Virginia, Kapidzic, Mirhan, ...
We studied the vascular effects of invasive human cytotrophoblasts in vivo by transplanting placental villi to the fifth mammary fat pads or beneath the kidney capsules of Scid mice. Over 3 weeks,...
Cha, Jennifer N., Shimizu, Katsuhiko, Zhou, Yan, Christiansen, Sean C., Chmelka, Bradley F., Stucky, Galen D., ...
Nanoscale control of the polymerization of silicon and oxygen determines the structures and properties of a wide range of siloxane-based materials, including glasses, ceramics, mesoporous molecular...
Poly(ADP-ribose) polymerase-1 is required for efficient HIV-1 integration
Ha, Hyo Chol, Juluri, Krishna, Zhou, Yan, Leung, Steve, Hermankova, Monika, Snyder, Solomon H.
Poly(ADP-ribose) polymerase-1 (PARP-1; EC 2.4.2.30) is an abundant nuclear enzyme, activated by DNA strand breaks to attach up to 200 ADP-ribose groups to nuclear proteins. As retroviral infection...
Gu, Bai-Wei, Xiong, Hui, Zhou, Yan, Chen, Bing, Wang, Li, Dong, Shuo, ...
The physiologic actions of retinoic acids (RAs) are mediated through RA receptors (RARs) and retinoid X receptors (RXRs). The RARα gene has drawn particular attention because it is the common target...
Pierson, Theodore C., Zhou, Yan, Kieffer, Tara L., Ruff, Christian T., Buck, Christopher, Siliciano, Robert F.
Most current evidence suggests that the infection of resting CD4+ T cells by human immunodeficiency virus type 1 (HIV-1) is not productive due to partial or complete blocks in the viral life cycle at...
Latency in Human Immunodeficiency Virus Type 1 Infection: No Easy Answers
Persaud, Deborah, Zhou, Yan, Siliciano, Janet M., Siliciano, Robert F.
Hermankova, Monika, Siliciano, Janet D., Zhou, Yan, Monie, Daphne, Chadwick, Karen, Margolick, Joseph B., ...
In individuals with human immunodeficiency virus type 1 (HIV-1) infection, a small reservoir of resting memory CD4+ T lymphocytes carrying latent, integrated provirus persists even in patients...
Zhang, Haili, Zhou, Yan, Alcock, Cecily, Kiefer, Tara, Monie, Daphne, Siliciano, Janet, ...
Human immunodeficiency virus type 1 (HIV-1)-infected individuals who develop drug-resistant virus during antiretroviral therapy may derive benefit from continued treatment for two reasons. First,...
Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface
Red-Horse, Kristy, Zhou, Yan, Genbacev, Olga, Prakobphol, Akraporn, Foulk, Russell, McMaster, Michael, ...
Trophoblasts, the specialized cells of the placenta, play a major role in implantation and formation of the maternal-fetal interface. Through an unusual differentiation process examined in this...
The analysis of large-scale gene expression correlated to the phase changes of the migratory locust
Kang, Le, Chen, XiangYong, Zhou, Yan, Liu, BoWan, Zheng, Wei, Li, RuiQiang, ...
The migratory locust is one of the most notorious agricultural pests that undergo a well known reversible, density-dependent phase transition from the solitary to the gregarious. To demonstrate the...
The Genomes of Oryza sativa: A History of Duplications
Yu, Jun, Wang, Jun, Lin, Wei, Li, Songgang, Li, Heng, Zhou, Jun, ...
We report improved whole-genome shotgun sequences for the genomes of indica and japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the drafts of 2002. Tested...
Kinetics of Human Immunodeficiency Virus Type 1 Decay following Entry into Resting CD4+ T Cells
Zhou, Yan, Zhang, Haili, Siliciano, Janet D., Siliciano, Robert F.
In untreated human immunodeficiency virus type 1 (HIV-1) infection, most viral genomes in resting CD4+ T cells are not integrated into host chromosomes. This unintegrated virus provides an inducible...
Monie, Daphne, Simmons, Rachel P., Nettles, Richard E., Kieffer, Tara L., Zhou, Yan, Zhang, Haili, ...
A latent reservoir for human immunodeficiency virus type 1 (HIV-1) consisting of integrated provirus in resting memory CD4+ T cells prevents viral eradication in patients on highly active...
Numb Proteins Specify Asymmetric Cell Fates via an Endocytosis- and Proteasome-Independent Pathway†
Tang, Haiyan, Rompani, Santiago B., Atkins, Joshua B., Zhou, Yan, Osterwalder, Thomas, Zhong, Weimin
Numb proteins are evolutionarily conserved signaling molecules that make the daughter cells different after asymmetric divisions by segregating to only one daughter. They contain distinct binding...
Wu, Terry H., Hutt, Julie A., Garrison, Kristin A., Berliba, Lyudmila S., Zhou, Yan, Lyons, C. Rick
The inhalation of Francisella tularensis biovar A causes pneumonic tularemia associated with high morbidity and mortality rates in humans. Exposure to F. tularensis usually occurs by accident, but...
Heterotachy and long-branch attraction in phylogenetics
Philippe, Hervé, Zhou, Yan, Brinkmann, Henner, Rodrigue, Nicolas, Delsuc, Frédéric
Nuclear Retention of Multiply Spliced HIV-1 RNA in Resting CD4+ T Cells
Lassen, Kara G, Ramyar, Kasra X, Bailey, Justin R, Zhou, Yan, Siliciano, Robert F
HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). We describe here a novel post-transcriptional block...
Red-Horse, Kristy, Rivera, Jose, Schanz, Andrea, Zhou, Yan, Winn, Virginia, Kapidzic, Mirhan, ...
We studied the vascular effects of invasive human cytotrophoblasts in vivo by transplanting placental villi to the fifth mammary fat pads or beneath the kidney capsules of Scid mice. Over 3 weeks,...
Invasive Cytotrophoblasts Manifest Evidence of Oxidative Stress in Preeclampsia
Many, Ariel, Hubel, Carl A., Fisher, Susan J., Roberts, James M., Zhou, Yan
In preeclampsia, poor placental perfusion may result in maternal endothelial dysfunction, but the pathways involved are largely unknown. Candidate placental mediators include products of oxidative...
Shen, Anding, Yang, Hung-Chih, Zhou, Yan, Chase, Amanda J., Boyer, Jean D., Zhang, Hao, ...
Although combination therapy allows the suppression of human immunodeficiency virus type 1 (HIV-1) viremia to undetectable levels, eradication has not been achieved because the virus persists in...
Porcine adenovirus type 3 E1Blarge protein downregulates the induction of IL-8
Zhou, Yan, Ficzycz, Andrew, Tikoo, Suresh Kumar
Replication-defective (E1-E3 deleted) adenovirus vector based gene delivery results in the induction of cytokines including IL-8, which may contribute to the development of inflammatory immune...
Beckstrom-Sternberg, Stephen M., Auerbach, Raymond K., Godbole, Shubhada, Pearson, John V., Beckstrom-Sternberg, James S., Deng, Zuoming, ...
Francisella tularensis is the causative agent of tularemia, which is a highly lethal disease from nature and potentially from a biological weapon. This species contains four recognized subspecies...
Lineage specification and plasticity in CD19− early B cell precursors
Rumfelt, Lynn L., Zhou, Yan, Rowley, Benjamin M., Shinton, Susan A., Hardy, Richard R.
We describe here three CD19− B cell precursor populations in mouse bone marrow identified using 12-color flow cytometry. Cell transfer experiments indicate lineage potentials consistent with...
Genome Biology of Actinobacillus pleuropneumoniae JL03, an Isolate of Serotype 3 Prevalent in China
Xu, Zhuofei, Zhou, Yan, Li, Liangjun, Zhou, Rui, Xiao, Shaobo, Wan, Yun, ...
Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a cause of considerable world wide economic losses in the swine industry. We sequenced the complete...
Evaluation of the models handling heterotachy in phylogenetic inference
Zhou, Yan, Rodrigue, Nicolas, Lartillot, Nicolas, Philippe, Hervé
Shin, Yeun-Kyung, Li, Yang, Liu, Qiang, Anderson, Deborah H., Babiuk, Lorne A., Zhou, Yan
Recent studies have demonstrated that influenza A virus infection activates the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway by binding of influenza NS1 protein to the p85 regulatory...
Drake, Penelope M., Gunn, Michael D., Charo, Israel F., Tsou, Chia-Lin, Zhou, Yan, Huang, Ling, ...
During human pregnancy, the specialized epithelial cells of the placenta (cytotrophoblasts) come into direct contact with immune cells in several locations. In the fetal compartment of the placenta,...
Network Economics and the Digital Divide in Rural India
Jake Kendall, Nirvikar Singh, Kristin Williams, Yan Zhou, P.D. Kaushik
The idea of a ‘global digital divide’ is well accepted, and cross-country studies of determinants of differences in computer and Internet penetration have identified income, telecommunications...
Network Economics and the Digital Divide in Rural South Asia
Jake Kendall, Nirvikar Singh, Kristin Williams, Yan Zhou, P.D. Kaushik
The concept of a ‘global digital divide’ is now common, and many cross-country studies of determinants of differences in computer and Internet penetration have been performed. The main...
Dobrowsky, Terrence M., Zhou, Yan, Sun, Sean X., Siliciano, Robert F., Wirtz, Denis
The fusion of human immunodeficiency virus type 1 (HIV-1) to host cells is a dynamic process governed by the interaction between glycoproteins on the viral envelope and the major receptor, CD4, and...
ROLE OF SOLVENT IN SLURRY PHASE REACTIONS
YAN ZHOU, KAI HU, JUNFENG SHEN, ZHENPING JI, GONGZHEN CHENG
There exists an optimal amount of solvent (generally water) that can be added to the slurry phase reaction between solid reactants; the reactivity and efficiency of such reactions are different from...
Ding, Lihua, Wang, Zhaoyun, Yan, Jinghua, Yang, Xiao, Liu, Aijun, Qiu, Weiyi, ...
The four-and-a-half LIM (FHL) proteins belong to a family of LIM-only proteins that regulate cell proliferation, differentiation, and apoptosis. The exact functions of each FHL protein in cancer...
Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism
Trachootham, Dunyaporn, Zhang, Hui, Zhang, Wan, Feng, Li, Du, Min, Zhou, Yan, ...
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia, and resistance to fludarabine-based therapies is a major challenge in CLL treatment. Because CLL cells are known to have elevated...
Zhou, Yan, Shen, Lin, Yang, Hung-Chih, Siliciano, Robert F.
CD4+ T-cell depletion is the hallmark of AIDS pathogenesis. Multiple mechanisms may contribute to the death of productively infected CD4+ T cells and innocent-bystander cells. In this study, we...
Finding genes in Schistosoma japonicum: annotating novel genomes with help of extrinsic evidence
Brejová, Broňa, Vinař, Tomáš, Chen, Yangyi, Wang, Shengyue, Zhao, Guoping, Brown, Daniel G., ...
We have developed a novel method for estimating the parameters of hidden Markov models for gene finding in newly sequenced species. Our approach does not rely on curated training data sets, but...
Amin, Rupesh H., Cado, Dragana, Nolla, Hector, Huang, Dan, Shinton, Susan A., Zhou, Yan, ...
Allelic exclusion of Ig gene expression is necessary to limit the number of functional receptors to one per B cell. The mechanism underlying allelic exclusion is unknown. Because germline...
Updating magnetic resonance imaging of small bowel: Imaging protocols and clinical indications
Zhu, Jiong, Xu, Jian-Rong, Gong, Hong-Xia, Zhou, Yan
High soft tissue contrast resolution, acquisition of multi-planar images and the possibility to obtain functional information make magnetic resonance an interesting imaging technique to evaluate the...
Tissue plasminogen activator modulates the cellular and behavioral response to cocaine
Maiya, Rajani, Zhou, Yan, Norris, Erin H., Kreek, Mary Jeanne, Strickland, Sidney
Cocaine exposure induces long-lasting molecular and structural adaptations in the brain. In this study, we show that tissue plasminogen activator (tPA), an extracellular protease involved in neuronal...
Zhang, Zhong-Wei, Kang, Yan, Deng, Li-Jing, Luo, Chuan-Xing, Zhou, Yan, Xue, Xin-Sheng, ...
We analyzed the clinical manifestations and experiences of diagnosing and treating central pontine myelinolysis following living donor liver transplantation. The clinical data of three patients with...
When data are missing at random, the missing-data mechanism can be ignored but this assumption is not always intuitive for general patterns of missing data. In part I, we consider maximum likelihood...
A Pair of Allelic WRKY Genes Play Opposite Roles in Rice-Bacteria Interactions1[C][W][OA]
Tao, Zeng, Liu, Hongbo, Qiu, Deyun, Zhou, Yan, Li, Xianghua, Xu, Caiguo, ...
Although allelic diversity of genes has been reported to play important roles in different physiological processes, information on allelic diversity of defense-responsive genes in host-pathogen...
MODELING HETEROTACHY IN PHYLOGENETICS
Il a été démontré que l’hétérotachie, variation du taux de substitutions au cours du temps et entre les sites, est un phénomène fréquent au sein de données réelles. Échouer à...
Yang, Hung-Chih, Xing, Sifei, Shan, Liang, O’Connell, Karen, Dinoso, Jason, Shen, Anding, ...
The development of highly active antiretroviral therapy (HAART) to treat individuals infected with HIV-1 has dramatically improved patient outcomes, but HAART still fails to cure the infection. The...