Zi-Jian Xie

Binding of Src to Na+/K+-ATPase Forms a Functional Signaling Complex

Tian, Jiang, Cai, Ting, Yuan, Zhaokan, Wang, Haojie, Liu, Lijun, Haas, Michael, ...

We have shown that ouabain activates Src, resulting in subsequent tyrosine phosphorylation of multiple effectors. Here, we tested if the Na+/K+-ATPase and Src can form a functional signaling complex....

Binding of Src to Na+/K+-ATPase Forms a Functional Signaling Complex

Tian, Jiang, Cai, Ting, Yuan, Zhaokan, Wang, Haojie, Liu, Lijun, Haas, Michael, ...

We have shown that ouabain activates Src, resulting in subsequent tyrosine phosphorylation of multiple effectors. Here, we tested if the Na+/K+-ATPase and Src can form a functional signaling complex....

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins

Brooks, Craig, Wei, Qingqing, Feng, Leping, Dong, Guie, Tao, Yanmei, Mei, Lin, ...

Mitochondrial injury, characterized by outer membrane permeabilization and consequent release of apoptogenic factors, is a key to apoptosis of mammalian cells. Bax and Bak, two multidomain Bcl-2...

Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase

Cai, Ting, Wang, Haojie, Chen, Yiliang, Liu, Lijun, Gunning, William T, Quintas, Luis Eduardo M., ...

Here, we show that the Na/K-ATPase interacts with caveolin-1 (Cav1) and regulates Cav1 trafficking. Graded knockdown of Na/K-ATPase decreases the plasma membrane pool of Cav1, which results in a...